Rome2Rio

How to get fromSikeston to Chicagoby taxi, plane, bus, train or car

Find Transport to Chicago

See all options

There are 6 ways to get from Sikeston to Chicago by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Cape Girardeau Municipal Airport, fly

    best
    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)plane plane CGI - ORD
    3h
    $133–259
  2. Drive 395.2 mi

    cheapest
    1. Drive from Sikeston to Chicagocar car 395.2 mi
    6h 32m
    $73–105
  3. Bus

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - Chicagobus bus Milwaukee
    8h 10m
    $104–226
  4. Taxi, train (Amtrak)

    1. Take the taxi from Sikeston to Fulton Amtrak Stationtaxi taxi
    2. Take the train from Fulton Amtrak Station to Homewoodtrain train City of New Orleans
    9h 24m
    $186–314
  5. Taxi to Barkley Regional Airport, fly

    1. Take the taxi from Sikeston to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)plane plane PAH - ORD
    3h 45m
    $317–1,752
  6. Bus to Williamson County Regional Airport, fly

    1. Take the bus from Flying J - Matthews to Marathon Gas Station - Marionbus bus
    2. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    5h 11m
    $135–354

Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD) flights

Calendar7Weekly Planes
Duration1h 40mAverage Duration
Ticket$62Cheapest Price
See schedules

Questions & Answers

What companies run services between Sikeston, MO, USA and Chicago, IL, USA?

Tornado Bus Company operates a bus from Flying J - Matthews to Tornado Bus Co - Chicago once daily. Tickets cost $75–190 and the journey takes 7h 24m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides