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How to get fromSiesta Key to Myrtle Beachby plane, car, train, bus, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Siesta Key to Myrtle Beach by plane, car, train, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Sarasota–Bradenton International Airport

    best
    1. Fly from Sarasota–Bradenton International Airport (SRQ) to Myrtle Beach (MYR)plane plane SRQ - MYR
    5h 42m
    $102–498

  2. Bus to Tampa, fly

    cheapest
    1. Take the bus from Sarasota Cattlemen Transfer Center to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    7h 8m
    $98–584

  3. Drive, train, bus

    1. Drive from Siesta Key to Tampacar car
    2. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    3. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain train
    4. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    15h 4m
    $167–353

  4. Bus

    1. Take the bus from Sarasota Cattlemen Transfer Center to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Camdenbus bus
    4. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    20h 29m
    $104–198

  5. Drive 576.3 mi

    1. Drive from Siesta Key to Myrtle Beachcar car 576.3 mi
    10h 46m
    $106–152

  6. Amtrak Thruway, train, bus

    1. Take the bus from Sarasota Amtrak Bus Stop to Orlando, FLbus bus
    2. Take the train from Orlando to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    18h 17m
    $188–356

Siesta Key to Myrtle Beach by bus

Calendar7Weekly Buses
Duration20h 29mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Siesta Key to Myrtle Beach.ExpandLaunch map view
  • Distance: 501.9 mi
  • Duration: 5h 42m

What companies run services between Siesta Key, FL, USA and Myrtle Beach, SC, USA?

American Airlines, Delta, and two other airlines fly from Sarasota–Bradenton International Airport (SRQ) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Ocean Blvd @ Avenida Madera NB to Myrtle Beach Bus Station via Main St @ Lemon Ave, Downtown Transfer Station, Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Orlando Bus Station, Jacksonville, and Camden in around 20h 29m.

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