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How to get fromSiesta Key to Myrtle Beachby plane, car, train, bus or bus (Flixbus, Greyhound)

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There are 6 ways to get from Siesta Key to Myrtle Beach by plane, car, train, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Sarasota–Bradenton International Airport

    best
    1. Fly from Sarasota–Bradenton International Airport (SRQ) to Myrtle Beach (MYR)planeSRQ - MYR
    5h 40m
    $182–566

  2. Drive 576.1 mi

    cheapest
    1. Drive from Siesta Key to Myrtle Beachcar576.1 mi
    10h 41m
    $106–152

  3. Drive, train, bus

    1. Drive from Siesta Key to Tampacar
    2. Take the train from Tampa to Kissimmee Amtrak Stationtrain
    3. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain
    4. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
    15h 29m
    $119–270

  4. Bus

    1. Take the bus from Sarasota Cattlemen Transfer Center to Orlando Bus Stationbus
    2. Take the bus from Orlando Bus Station to Florence Bus Stationbus
    3. Take the bus from Florence to Myrtle Beach, SCbus
    18h 29m
    $116–294

  5. Bus to Tampa, fly

    1. Take the bus from Sarasota Cattlemen Transfer Center to Tampa Bus Stationbus
    2. Fly from Tampa (TPA) to Myrtle Beach (MYR)planeTPA - MYR
    6h 52m
    $140–362

  6. Amtrak Thruway, train, bus

    1. Take the bus from Sarasota Amtrak Bus Stop to Orlando, FLbus
    2. Take the train from Orlando to Charleston Amtrak Stationtrain
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
    18h 42m

Siesta Key to Myrtle Beach by bus

Calendar7Weekly Buses
Duration18h 29mAverage Duration
Ticket$116Cheapest Price
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Questions & Answers

What companies run services between Siesta Key, FL, USA and Myrtle Beach, SC, USA?

American Airlines, Delta, and Southwest Airlines fly from Sarasota–Bradenton International Airport (SRQ) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Ocean Blvd @ Avenida Madera NB to Myrtle Beach, SC via Main St @ Lemon Ave, Downtown Transfer Station, Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Orlando Bus Station, Florence Bus Station, and Florence in around 18h 29m.

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