There are 5 ways to get from Siesta Key to Key West (Island) by bus, ferry, bus (Greyhound), car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, ferry
best- Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus FlixBus 2421
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
8h 38m$184–204Fly
cheapest- Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)plane SRQ - EYW
5h 57m$62–404Bus
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus Tallahassee
- Take the bus from Miami Airport Station to Key West Airportbus Greyhound US0720s
11h 39m$78–118Drive 346.7 mi
- Drive from Siesta Key to Key Westcar 346.7 mi
7h 5m$64–92Bus, shuttle
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Key West, FLTo the Keys
11h 55m$224–278
Siesta Key to Key West (Island) by bus and tram
Comparing Your Travel Options
The cheapest way to get from Siesta Key to Key West (Island) is to drive which costs $60 - $95 and takes 7h 5m.
The fastest way to get from Siesta Key to Key West (Island) is to fly which takes 5h 57m and costs $60 - $410.
No, there is no direct bus from Siesta Key to Key West (Island). However, there are services departing from Ocean Blvd @ Avenida Madera NB and arriving at Key West Airport via Downtown Transfer Station, Bradenton/Sarasota - Mobil Gas Station and Miami Airport Station. The journey, including transfers, takes approximately 11h 39m.
The distance between Siesta Key and Key West (Island) is 245 miles. The road distance is 348.7 miles.
The best way to get from Siesta Key to Key West (Island) without a car is to bus and ferry which takes 8h 38m and costs $180 - $210.
It takes approximately 8h 38m to get from Siesta Key to Key West (Island), including transfers.
Siesta Key to Key West (Island) bus services, operated by RedCoach, depart from Bradenton/Sarasota - Mobil Gas Station.
The best way to get from Siesta Key to Key West (Island) is to bus which takes 11h 39m and costs $75 - $120. Alternatively, you can fly, which costs $60 - $410 and takes 5h 57m.
Siesta Key to Key West (Island) bus services, operated by RedCoach, arrive at Miami Airport station.
Yes, the driving distance between Siesta Key to Key West (Island) is 349 miles. It takes approximately 7h 5m to drive from Siesta Key to Key West (Island).
What companies run services between Siesta Key, FL, USA and Key West (Island), FL, USA?
You can take a bus from Ocean Blvd @ Avenida Madera NB to Key West Airport via Main St @ Lemon Ave, Downtown Transfer Station, Cattlemen Rd @ Fruitville Rd, Bradenton/Sarasota - Mobil Gas Station, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, and Miami Airport Station in around 11h 39m. Alternatively, American Airlines, Delta, and Allegiant Air fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW) every 4 hours.
- Website
- delta.com
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $120–600
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 969+ hotels available in Key West (Island).





