There are 5 ways to get from Siesta Key to Key West (Island) by bus, ferry, bus (Greyhound), car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, ferry
best- Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus FlixBus 2421
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
8h 49m$182–208Bus
cheapest- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus Tallahassee-Miami
- Take the bus from Miami Airport Station to Key West Airportbus Greyhound US0720s
11h 59m$48–188Drive 346.7 mi
- Drive from Siesta Key to Key Westcar 346.7 mi
7h 5m$64–92Fly
- Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)plane SRQ - EYW
6h 39m$412–704Bus, shuttle
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus Tallahassee-Miami
- Take a shuttle bus from Miami, FL - International Airport to Key West, FLTo the Keys
12h 15m$178–344
Siesta Key to Key West (Island) by bus and tram
Questions & Answers
The cheapest way to get from Siesta Key to Key West (Island) is to drive which costs $60 - $95 and takes 7h 5m.
The fastest way to get from Siesta Key to Key West (Island) is to fly which takes 6h 39m and costs $410 - $750.
The distance between Siesta Key and Key West (Island) is 245 miles. The road distance is 348.7 miles.
The best way to get from Siesta Key to Key West (Island) without a car is to bus and ferry which takes 8h 49m and costs $180 - $210.
It takes approximately 8h 49m to get from Siesta Key to Key West (Island), including transfers.
The best way to get from Siesta Key to Key West (Island) is to bus which takes 11h 59m and costs $45 - $190. Alternatively, you can fly, which costs $410 - $750 and takes 6h 39m.
Yes, the driving distance between Siesta Key to Key West (Island) is 349 miles. It takes approximately 7h 5m to drive from Siesta Key to Key West (Island).
There are 739+ hotels available in Key West (Island).
What companies run services between Siesta Key, FL, USA and Key West (Island), FL, USA?
You can take a bus from Ocean Blvd @ Avenida Madera NB to Key West Airport via Main St @ Lemon Ave, Downtown Transfer Station, Cattlemen Rd @ Fruitville Rd, Bradenton/Sarasota - Mobil Gas Station, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, and Miami Airport Station in around 11h 59m. Alternatively, American Airlines and Delta fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW) every 4 hours.
- Website
- delta.com
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $160–850
- Website
- aa.com
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–600
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $180–900
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $18–35
- Schedules at
- flixbus.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airport
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $24–140
- Website
- https://www.redcoachusa.com
- Web
- $24–140
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–45
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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