There are 8 ways to get from Siena to Madrid by train, plane, train (Renfe, Ouigo), bus, car, or train (Trenitalia, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly
best- Take the train from Siena to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Adolfo Suárez Madrid–Barajas Airport (MAD)FLR - MAD
6h 47m€62–195Train via Barcelona
- Take the train from Siena to Firenze S.M.N.Re
- Take the train from Florence Santa Maria Novella to Milano Centrale
- Take the train from Milano Centrale to Lyon Part DieuFr
- Take the train from Lyon Part Dieu to Barcelona-Sants
- Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena GrandesAve
18h 46m€168–465Bus
- Take the bus from Siena to Florence Villa Constanza Bus Station443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Genoa510 / ...
- Take the bus from Genoa to Madrid
26h 30m€95–263Drive 1,674.9 km
- Drive from Siena to Madrid1,674.9 km
17h 9m€260–375Train, train to Pisa International Airport, fly
- Take the train from Siena to Empoli
- Take the train from Empoli to Pisa Centrale
- Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)PSA - MAD
6h 45m€72–213Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Siena to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Bologna Centrale
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Adolfo Suárez Madrid–Barajas Airport (MAD)BLQ - MAD
7h 25m€73–262Train
- Take the train from Siena to EmpoliRe
- Take the train from Empoli to Pisa CentraleRe
- Take the train from Pisa Centrale to VentimigliaIc
- Take the train from Ventimiglia to Marseille St Charles
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
21h 18m€143–213Bus, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazione131
- Take the train from Florence Santa Maria Novella to Torino - Porta Nuova
- Take the bus from Turin Corso Vittorio Emanuele II to Madrid Mendez Alvaro Estacion Sur
30h 32m
Siena to Madrid by train
Questions & Answers
The cheapest way to get from Siena to Madrid is to train and fly which costs €60 - €200 and takes 6h 47m.
The fastest way to get from Siena to Madrid is to train and fly which takes 6h 45m and costs €70 - €220.
No, there is no direct bus from Siena to Madrid. However, there are services departing from Siena and arriving at Madrid via Florence Villa Constanza Bus Station and Genoa. The journey, including transfers, takes approximately 26h 30m.
No, there is no direct train from Siena to Madrid. However, there are services departing from Siena and arriving at Madrid-Puerta de Atocha-Almudena Grandes via Florence Santa Maria Novella, Milano Centrale, Lyon Part Dieu and Barcelona-Sants. The journey, including transfers, takes approximately 18h 46m.
The distance between Siena and Madrid is 1380 km. The road distance is 1674.9 km.
The best way to get from Siena to Madrid without a car is to train via Barcelona which takes 18h 46m and costs €160 - €470.
It takes approximately 6h 47m to get from Siena to Madrid, including transfers.
Siena to Madrid bus services, operated by FlixBus, depart from Siena station.
Siena to Madrid train services, operated by Trenitalia S.p.A., depart from Siena station.
The best way to get from Siena to Madrid is to train via Barcelona which takes 18h 46m and costs €160 - €470. Alternatively, you can bus, which costs €95 - €270 and takes 26h 30m.
What companies run services between Siena, Italy and Madrid, Spain?
You can take a train from Siena to Madrid-Puerta de Atocha-Almudena Grandes via Florence Santa Maria Novella, Milano Centrale, Lyon Part Dieu, and Barcelona-Sants in around 18h 46m. Alternatively, you can take a bus from Siena to Madrid via Florence Villa Constanza Bus Station and Genoa in around 26h 30m.
- Website
- ryanair.com
Flights from Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- €40–180
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- €45–150
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Palma Mallorca
- Ave. Duration
- 5h 20m
- When
- Tuesday
- Estimated price
- €45–150
- Website
- iberia.com
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €50–170
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- €50–170
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €55–150
- Website
- vueling.com
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €50–170
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- €50–170
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 50m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Ventimiglia to Marseille St Charles
- Ave. Duration
- 3h 57m
- Frequency
- Once a week
- Estimated price
- €15–23
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Torino - Porta Nuova
- Ave. Duration
- 3h 5m
- Frequency
- Every 3 hours
- Estimated price
- €35–85
- Website
- https://www.italotreno.it/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Lyon Part Dieu to Barcelona-Sants
- Ave. Duration
- 4h 48m
- Frequency
- Once daily
- Estimated price
- €50–75
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- Twice daily
- Estimated price
- €45–65
- Website
- https://www.renfe.com/es/en
Train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 48m
- Frequency
- Once daily
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €45–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 2h 59m
- Frequency
- Hourly
- Estimated price
- €45–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 2h 52m
- Frequency
- Every 4 hours
- Estimated price
- €35–85
- Website
- https://www.ouigo.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 33m
- Frequency
- Once daily
- Estimated price
- €29–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–19
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Genoa
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €8–29
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Madrid
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €80–200
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- €12–13
- Website
- https://www.itabus.it/en/home
Bus from Florence Villa Constanza Bus Station to Genoa
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a week
- Estimated price
- €10–45
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–10
- Website
- https://marinobus.it/en/
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Turin Corso Vittorio Emanuele II to Madrid Mendez Alvaro Estacion Sur
- Ave. Duration
- 24h
- Frequency
- Twice a week
- Estimated price
- €65–95
- Website
- https://union-ivkoni.com/en
Want to know more about travelling around Spain
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More Questions & Answers
Siena to Madrid bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to Madrid train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Madrid is 1675 km. It takes approximately 17h 9m to drive from Siena to Madrid.
Book your Siena to Madrid train tickets online with Omio.
Book your Siena to Madrid bus tickets online with Omio and FlixBus.
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