There are 8 ways to get from Siena to Madrid by bus, plane, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Florence Peretola Airport, fly
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane FLR - MAD
6h 34mBus
cheapest- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Barcelona - North Bus Stationbus
- Take the bus from Barcelona, Estació d'Autobusos Nord to Madrid, Avenida de Américabus
27h 5m€67–159Bus, train via Barcelona
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Barcelona-Santstrain
- Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain Ave
18h 46mDrive 1,674.7 km
- Drive from Siena to Madridcar 1,674.7 km
17h 15m€258–373Train, train to Pisa International Airport, fly
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane PSA - MAD
6h 52m€78–213Bus, train to Bologna Guglielmo Marconi Airport, fly
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane BLQ - MAD
7h 14mTrain, bus
- Take the train from Siena to Firenze S.M.N.train Re
- Take the bus from Florence to Marseille, Gare de Marseille-Saint-Charlesbus
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
21h 17m€129–195Bus, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Florence Santa Maria Novella to Torino - Porta Nuovatrain
- Take the bus from Turin Corso Vittorio Emanuele II to Madrid Mendez Alvaro Estacion Surbus
30h 32m
Florence Peretola Airport (FLR) to Adolfo Suárez Madrid–Barajas Airport (MAD) flights
Questions & Answers
The cheapest way to get from Siena to Madrid is to bus which costs €65 - €160 and takes 27h 5m.
The fastest way to get from Siena to Madrid is to train and fly which takes 6h 52m and costs €75 - €220.
No, there is no direct bus from Siena to Madrid. However, there are services departing from Siena and arriving at Madrid, Avenida de América via Florence Villa Constanza Bus Station and Barcelona, Estació d'Autobusos Nord. The journey, including transfers, takes approximately 27h 5m.
The distance between Siena and Madrid is 1356 km. The road distance is 1674.7 km.
The best way to get from Siena to Madrid without a car is to bus and train via Barcelona which takes 18h 46m and costs .
It takes approximately 6h 34m to get from Siena to Madrid, including transfers.
Siena to Madrid bus services, operated by FlixBus, depart from Siena station.
Siena to Madrid bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Yes, the driving distance between Siena to Madrid is 1675 km. It takes approximately 17h 15m to drive from Siena to Madrid.
Book your Siena to Madrid bus tickets online with Omio.
What companies run services between Siena, Italy and Madrid, Spain?
You can take a bus from Siena to Madrid, Avenida de América via Florence Villa Constanza Bus Station and Barcelona, Estació d'Autobusos Nord in around 27h 5m.
- Website
- ryanair.com
Flights from Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–180
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €50–150
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Palma Mallorca
- Ave. Duration
- 5h 50m
- When
- Friday
- Estimated price
- €50–150
- Website
- iberia.com
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €50–140
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Monday to Friday
- Estimated price
- €50–140
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €55–170
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 5h
- When
- Monday to Friday
- Estimated price
- €35–190
- Website
- vueling.com
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €50–140
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Monday to Friday
- Estimated price
- €50–140
Flights from Bologna Guglielmo Marconi Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 5h
- When
- Monday to Friday
- Estimated price
- €35–190
- Website
- volotea.com
Flights from Florence Peretola Airport to Adolfo Suárez Madrid–Barajas Airport via Lyon
- Ave. Duration
- 5h 40m
- When
- Monday and Friday
- Estimated price
- €65–200
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Torino - Porta Nuova
- Ave. Duration
- 3h 5m
- Frequency
- Every 3 hours
- Estimated price
- €35–85
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €50–110
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Lyon Part Dieu to Barcelona-Sants
- Ave. Duration
- 4h 48m
- Frequency
- Once daily
- Estimated price
- €50–75
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 28m
- Frequency
- Twice daily
- Estimated price
- €45–65
- Website
- https://www.renfe.com/es/en
Train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 8h 17m
- Frequency
- Once daily
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €35–110
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 20m
- Frequency
- Hourly
- Estimated price
- €35–95
- Website
- https://iryo.eu/en/home
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 17m
- Frequency
- Every 4 hours
- Estimated price
- €29–60
- Website
- https://www.ouigo.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–14
- Website
- https://www.flixbus.co.uk
Bus from Florence to Marseille, Gare de Marseille-Saint-Charles
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- €29–55
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- €6–13
- Website
- https://www.itabus.it/en/home
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Florence Villa Constanza Bus Station to Barcelona - North Bus Station
- Ave. Duration
- 16h 25m
- Frequency
- Twice daily
- Estimated price
- €35–90
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Barcelona, Estació d'Autobusos Nord to Madrid, Avenida de América
- Ave. Duration
- 7h 50m
- Frequency
- Every 3 hours
- Estimated price
- €25–55
- Website
- https://www.alsa.com/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Turin Corso Vittorio Emanuele II to Madrid Mendez Alvaro Estacion Sur
- Ave. Duration
- 24h
- Frequency
- Twice a week
- Estimated price
- €65–95
- Website
- https://union-ivkoni.com/en
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