There are 8 ways to get from Siena to Luthern by bus, train, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Arth-Goldautrain Ec
8h 13mCHF 84–225Bus
cheapest- Take the bus from Siena to Milanbus FlixBus 519
- Take the bus from Milan to Luzernbus FlixBus N401 / ...
10hCHF 35–62Drive 604.1 km
- Drive from Siena to Lutherncar 604.1 km
6h 15mCHF 97–140Bus to Florence Peretola Airport, fly to Zurich Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Zurich Airport (ZRH)plane FLR - ZRH
- Take the train from Zürich HB to Luzerntrain
6h 6mCHF 106–287Train (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re / ...
- Take the train from Firenze S.M.N. to Arth-Goldautrain Ec
10h 11mCHF 114–218Bus, train via Locarno
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Locarnotrain
- Take the train from Locarno to Luzerntrain
10h 56mCHF 134–365Bus, train to Bologna Guglielmo Marconi Airport, fly to Zurich Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Zurich Airport (ZRH)plane BLQ - ZRH
- Take the train from Zürich HB to Luzerntrain
6h 51mCHF 102–340Bus to Florence Peretola Airport, fly to Basel, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Basel (BSL)plane FLR - BSL
- Take the train from Basel SBB to Luzerntrain
9h 4mCHF 139–337
Siena to Luthern by bus and train
Questions & Answers
The cheapest way to get from Siena to Luthern is to bus which costs SFr 35 - SFr 65 and takes 10h.
The fastest way to get from Siena to Luthern is to bus and fly and train which takes 6h 6m and costs SFr 100 - SFr 290.
No, there is no direct bus from Siena to Luthern. However, there are services departing from Siena and arriving at Luzern via Milan. The journey, including transfers, takes approximately 10h.
No, there is no direct train from Siena to Luthern. However, there are services departing from Siena and arriving at Luzern via Firenze S.M.N. and Arth-Goldau. The journey, including transfers, takes approximately 10h 11m.
The distance between Siena and Luthern is 606 km. The road distance is 604.1 km.
The best way to get from Siena to Luthern without a car is to bus and train which takes 8h 13m and costs SFr 80 - SFr 230.
It takes approximately 8h 13m to get from Siena to Luthern, including transfers.
Siena to Luthern bus services, operated by FlixBus, depart from Siena station.
Siena to Luthern train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Luthern is to bus which takes 10h and costs SFr 35 - SFr 65. Alternatively, you can train, which costs SFr 110 - SFr 220 and takes 10h 11m.
What companies run services between Siena, Italy and Luthern, Switzerland?
You can take a bus from Siena to Luzern via Milan in around 10h. Alternatively, you can take a train from Siena to Luzern via Firenze S.M.N. and Arth-Goldau in around 10h 11m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- CHF 70–170
Flights from Florence Peretola Airport to Zurich Airport via Rome
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- CHF 70–230
Flights from Bologna Guglielmo Marconi Airport to Zurich Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 70–230
- Website
- swiss.com
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- CHF 70–170
Flights from Florence Peretola Airport to Zurich Airport via Rome
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- CHF 70–230
Flights from Bologna Guglielmo Marconi Airport to Zurich Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 70–230
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Zurich Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- CHF 100–550
Flights from Bologna Guglielmo Marconi Airport to Zurich Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- CHF 95–430
Flights from Florence Peretola Airport to Basel via Frankfurt
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- CHF 130–750
Flights from Florence Peretola Airport to Basel via Munich
- Ave. Duration
- 6h 17m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- CHF 120–650
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Basel via Frankfurt
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- CHF 130–750
Flights from Florence Peretola Airport to Basel via Munich
- Ave. Duration
- 6h 35m
- When
- Sunday
- Estimated price
- CHF 120–650
- Website
- easyjet.com
Flights from Florence Peretola Airport to Basel via Rome
- Ave. Duration
- 3h 35m
- When
- Monday
- Estimated price
- CHF 100–250
Flights from Florence Peretola Airport to Basel via Nice
- Ave. Duration
- 4h 30m
- When
- Monday
- Estimated price
- CHF 100–250
- Website
- airfrance.com
Flights from Florence Peretola Airport to Basel via Paris Charles de Gaulle
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- CHF 65–370
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 35–80
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- CHF 11–23
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- CHF 27–65
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- CHF 8–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Arth-Goldau
- Ave. Duration
- 2h 32m
- Frequency
- Every 2 hours
- Estimated price
- CHF 45–90
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 60–90
- 2nd Class
- CHF 45–60
Train from Firenze S.M.N. to Arth-Goldau
- Ave. Duration
- 6h 52m
- Frequency
- Once daily
- Estimated price
- CHF 95–150
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 100–150
- 2nd Class
- CHF 95–130
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- CHF 24–65
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 45–65
- 2nd Class
- CHF 24–35
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 17–50
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Locarno
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 35–110
- Website
- https://www.sbb.ch/en
Train from Locarno to Luzern
- Ave. Duration
- 1h 39m
- Frequency
- Once a week
- Estimated price
- CHF 60–180
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 30–85
- Website
- https://www.sbb.ch/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- CHF 10–18
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- CHF 10–18
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- 4 times a day
- Estimated price
- CHF 35–70
- Website
- https://www.italotreno.it/en
- Phone
- +41 58 580 70 70
- info@sob.ch
- Website
- sob.ch
Train from Locarno to Luzern
- Ave. Duration
- 3h 8m
- Frequency
- Every 4 hours
- Schedules at
- sob.ch
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Schedules at
- sob.ch
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Milan
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- CHF 22–40
- Website
- https://www.flixbus.co.uk
Bus from Milan to Luzern
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- CHF 13–24
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Switzerland
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More Questions & Answers
Siena to Luthern bus services, operated by FlixBus, arrive at Milan station.
Siena to Luthern train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Luthern is 604 km. It takes approximately 6h 15m to drive from Siena to Luthern.
Book your Siena to Luthern train tickets online with Omio.
Book your Siena to Luthern bus tickets online with Omio and FlixBus.
There are 620+ hotels available in Luthern.




































