There are 8 ways to get from Siena to Lucerne by bus, train, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Arth-Goldautrain Ec
8h 3mCHF 86–200Bus
cheapest- Take the bus from Siena to Milanbus FlixBus 519
- Take the bus from Milan to Luzernbus FlixBus N401 / ...
10hCHF 40–67Drive 604.2 km
- Drive from Siena to Lucernecar 604.2 km
6h 15mCHF 98–142Bus to Florence Peretola Airport, fly to Zurich Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Zurich Airport (ZRH)plane FLR - ZRH
- Take the train from Zürich HB to Luzerntrain
6h 6mCHF 127–342Train (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re / ...
- Take the train from Firenze S.M.N. to Arth-Goldautrain Ec
10h 10mCHF 119–192Bus, train via Bellinzona
- Take the bus from Siena Central Train Station to Milan Malpensa Terminal 2 Arrivalsbus
- Take the train from Malpensa Aeroporto T2 to Bellinzonatrain S50
- Take the train from Bellinzona to Luzerntrain Ec / ...
11h 24mCHF 71–112Bus, train to Bologna Guglielmo Marconi Airport, fly to Zurich Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Zurich Airport (ZRH)plane BLQ - ZRH
- Take the train from Zürich HB to Luzerntrain
6h 47mCHF 113–385Bus to Florence Peretola Airport, fly to Basel, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Basel (BSL)plane FLR - BSL
- Take the train from Basel SBB to Luzerntrain
9h 11mCHF 139–327
Siena to Lucerne by bus and train
Questions & Answers
The cheapest way to get from Siena to Lucerne is to bus which costs SFr 40 - SFr 70 and takes 10h.
The fastest way to get from Siena to Lucerne is to bus and fly and train which takes 6h 6m and costs SFr 120 - SFr 350.
No, there is no direct bus from Siena to Lucerne. However, there are services departing from Siena and arriving at Luzern via Milan. The journey, including transfers, takes approximately 10h.
No, there is no direct train from Siena to Lucerne. However, there are services departing from Siena and arriving at Luzern via Firenze S.M.N. and Arth-Goldau. The journey, including transfers, takes approximately 10h 10m.
The distance between Siena and Lucerne is 606 km. The road distance is 604.2 km.
The best way to get from Siena to Lucerne without a car is to bus and train which takes 8h 3m and costs SFr 85 - SFr 200.
It takes approximately 8h 3m to get from Siena to Lucerne, including transfers.
Siena to Lucerne bus services, operated by FlixBus, depart from Siena station.
Siena to Lucerne train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Lucerne is to bus which takes 10h and costs SFr 40 - SFr 70. Alternatively, you can train, which costs SFr 110 - SFr 200 and takes 10h 10m.
What companies run services between Siena, Italy and Lucerne, Switzerland?
You can take a bus from Siena to Luzern via Milan in around 10h. Alternatively, you can take a train from Siena to Luzern via Firenze S.M.N. and Arth-Goldau in around 10h 10m.
- Website
- swiss.com
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- CHF 90–300
Flights from Bologna Guglielmo Marconi Airport to Zurich Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- CHF 80–370
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Basel via Frankfurt
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- CHF 210–950
Flights from Florence Peretola Airport to Basel via Munich
- Ave. Duration
- 5h 20m
- When
- Wednesday, Saturday, and Sunday
- Estimated price
- CHF 190–850
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Basel via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Monday, Saturday, and Sunday
- Estimated price
- CHF 210–950
Flights from Florence Peretola Airport to Basel via Munich
- Ave. Duration
- 6h 30m
- When
- Sunday
- Estimated price
- CHF 190–850
- Website
- austrian.com
Flights from Florence Peretola Airport to Basel via Vienna
- Ave. Duration
- 4h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 120–500
- Website
- airfrance.com
Flights from Florence Peretola Airport to Basel via Paris Charles de Gaulle
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- CHF 85–450
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 40–80
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 12–24
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- CHF 35–75
- Website
- https://www.italotreno.it/en
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 41 min
- Frequency
- Twice daily
- Estimated price
- CHF 10–22
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- CHF 29–65
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- CHF 8–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Arth-Goldau
- Ave. Duration
- 2h 32m
- Frequency
- Hourly
- Estimated price
- CHF 45–90
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 60–90
- 2nd Class
- CHF 45–60
Train from Firenze S.M.N. to Arth-Goldau
- Ave. Duration
- 6h 52m
- Frequency
- Once daily
- Estimated price
- CHF 100–150
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 100–150
- 2nd Class
- CHF 100–130
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- CHF 24–65
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 45–65
- 2nd Class
- CHF 24–35
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 18–55
- Website
- https://www.sbb.ch/en
Train from Bellinzona to Luzern
- Ave. Duration
- 1h 24m
- Frequency
- Every 3 hours
- Estimated price
- CHF 45–140
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 30–90
- Website
- https://www.sbb.ch/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- CHF 10–18
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- CHF 10–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T2 to Bellinzona
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- CHF 7–9
- Website
- https://www.trenord.it/en/
- Phone
- +41 58 580 70 70
- Website
- sob.ch
Train from Bellinzona to Luzern
- Ave. Duration
- 2h 42m
- Frequency
- Every 4 hours
- Estimated price
- CHF 40–60
- Schedules at
- sob.ch
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–45
- Schedules at
- sob.ch
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Siena to Milan
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- CHF 24–45
- Website
- https://www.flixbus.co.uk
Bus from Milan to Luzern
- Ave. Duration
- 3h 20m
- Frequency
- 3 times a day
- Estimated price
- CHF 15–26
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena Central Train Station to Milan Malpensa Terminal 2 Arrivals
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- CHF 23–45
- Website
- https://www.itabus.it/en/home
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More Questions & Answers
Siena to Lucerne bus services, operated by FlixBus, arrive at Milan station.
Siena to Lucerne train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Lucerne is 604 km. It takes approximately 6h 15m to drive from Siena to Lucerne.
Book your Siena to Lucerne train tickets online with Omio.
Book your Siena to Lucerne bus tickets online with Omio and FlixBus.
There are 658+ hotels available in Lucerne.
















































