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How to get fromSiena to Lucerneby train (Trenitalia), bus, car, train, or plane

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There are 7 ways to get from Siena to Lucerne by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Milan

    best
    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train Fr
    3. Take the train from Bologna centrale to Milano Centraletrain train
    4. Take the train from Milano Centrale to Arth-Goldautrain train Ec
    8h 9m
    CHF 94–221

  2. Bus, train

    cheapest
    1. Take the bus from Siena Central Train Station to Milan Malpensa Terminal 2 Arrivalsbus bus
    2. Take the train from Malpensa Aeroporto T2 to Bellinzonatrain train S50
    3. Take the train from Bellinzona to Luzerntrain train Ec / ...
    11h 24m
    CHF 67–104

  3. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Comobus bus
    3. Take the bus from Como to Luzernbus bus
    9h 10m
    CHF 72–114

  4. Drive  604.2 km

    1. Drive from Siena to Lucernecar car 604.2 km
    6h 15m
    CHF 115–166

  5. Train to Florence Peretola Airport, fly, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Zurich Airport (ZRH)plane plane FLR - ZRH
    3. Take the train from Zürich HB to Luzerntrain train
    6h 25m
    CHF 121–340

  6. Train (Trenitalia)

    1. Take the train from Siena to Firenze S.M.N.train train Re / ...
    2. Take the train from Firenze S.M.N. to Arth-Goldautrain train Ec
    10h 10m
    CHF 112–176

  7. Train, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Zurich Airport (ZRH)plane plane BLQ - ZRH
    4. Take the train from Zürich HB to Luzerntrain train
    7h 12m
    CHF 113–383

Siena to Lucerne by train

Calendar82Weekly Trains
Duration8h 9mAverage Duration
TicketCHF 94Cheapest Price
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Comparing Your Travel Options

Map of how to get from Siena to Lucerne.ExpandLaunch map view
  • Distance: 629 km
  • Duration: 8h 9m

What companies run services between Siena, Italy and Lucerne, Switzerland?

You can take a train from Siena to Luzern via Firenze S.M.N., Bologna centrale, Milano Centrale, and Arth-Goldau in around 8h 9m. Alternatively, you can take a bus from Siena to Luzern via Florence Villa Constanza Bus Station, Como, Como - Chiesa di San Zenone, Como S. Rocchetto, and Como in around 9h 10m.

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