There are 8 ways to get from Siena to Interlaken by bus, train, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Spieztrain Ec
8h 17mBus
cheapest- Take the bus from Siena Central Train Station to Zurich Ausstellungsstrassebus Itabus
- Take the bus from Zürich HB Schweizerhof to Interlaken Sonnenhofbus Shuttler L1 online shuttle
14h 37mCHF 49–86Bus, train via Domodossola
- Take the bus from Siena Central Train Station to Milan Malpensa Airport 1 P13bus
- Take the bus from Aeroporto Malpensa - Terminal 1 to Domodossola - Stazione Ferroviariabus 3
- Take the train from Domodossola to Muelenentrain Re / ...
12h 40mCHF 56–87Drive 622.5 km
- Drive from Siena to Interlakencar 622.5 km
6h 46mCHF 98–142Bus to Florence Peretola Airport, fly to Zurich Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Zurich Airport (ZRH)plane FLR - ZRH
- Take the train from Zürich Flughafen to Berntrain
- Take the train from Bern to Interlaken Westtrain
7h 51mTrain (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Spieztrain Ec
8h 29mCHF 78–186Bus to Florence Peretola Airport, fly to Basel, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Basel (BSL)plane FLR - BSL
- Take the train from Basel SBB to Interlaken Westtrain
10h 8mBus, train to Bologna Guglielmo Marconi Airport, fly to Zurich Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Zurich Airport (ZRH)plane BLQ - ZRH
- Take the train from Zürich Flughafen to Berntrain
- Take the train from Bern to Interlaken Westtrain
8h 30m
Florence Peretola Airport (FLR) to Zurich Airport (ZRH) flights
Questions & Answers
The cheapest way to get from Siena to Interlaken is to bus and train via Domodossola which costs SFr 55 - SFr 90 and takes 12h 40m.
The fastest way to get from Siena to Interlaken is to drive which takes 6h 46m and costs SFr 95 - SFr 150.
No, there is no direct bus from Siena station to Interlaken. However, there are services departing from Siena Central Train Station and arriving at Interlaken Sonnenhof via Zürich HB Schweizerhof. The journey, including transfers, takes approximately 14h 37m.
No, there is no direct train from Siena to Interlaken. However, there are services departing from Siena and arriving at Interlaken West via Firenze S.M.N., Milano Centrale and Spiez. The journey, including transfers, takes approximately 8h 29m.
The distance between Siena and Interlaken is 610 km. The road distance is 622.5 km.
The best way to get from Siena to Interlaken without a car is to bus and train which takes 8h 17m and costs .
It takes approximately 8h 17m to get from Siena to Interlaken, including transfers.
Siena to Interlaken bus services, operated by Itabus S.p.A., depart from Siena Central Train Station.
Siena to Interlaken train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Interlaken is to train which takes 8h 29m and costs SFr 75 - SFr 190. Alternatively, you can bus, which costs SFr 45 - SFr 90 and takes 14h 37m.
What companies run services between Siena, Italy and Interlaken, Switzerland?
You can take a train from Siena to Interlaken West via Firenze S.M.N., Milano Centrale, and Spiez in around 8h 29m. Alternatively, you can take a bus from Siena Central Train Station to Interlaken Sonnenhof via Zurich Ausstellungsstrasse and Zürich HB Schweizerhof in around 14h 37m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- CHF 70–190
Flights from Florence Peretola Airport to Zurich Airport via Rome
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- CHF 65–250
Flights from Bologna Guglielmo Marconi Airport to Zurich Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 75–380
- Website
- swiss.com
Flights from Florence Peretola Airport to Zurich Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- CHF 70–190
Flights from Florence Peretola Airport to Zurich Airport via Rome
- Ave. Duration
- 3h 20m
- When
- Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 65–250
Flights from Bologna Guglielmo Marconi Airport to Zurich Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 75–380
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Zurich Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- CHF 100–320
Flights from Florence Peretola Airport to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 25m
- When
- Thursday and Sunday
- Estimated price
- CHF 80–320
Flights from Florence Peretola Airport to Basel via Frankfurt
- Ave. Duration
- 3h 42m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- CHF 130–390
Flights from Florence Peretola Airport to Basel via Munich
- Ave. Duration
- 6h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 120–380
Flights from Bologna Guglielmo Marconi Airport to Zurich Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- CHF 90–280
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Basel via Frankfurt
- Ave. Duration
- 3h 42m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- CHF 130–390
- Website
- easyjet.com
Flights from Florence Peretola Airport to Basel via Rome
- Ave. Duration
- 5h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- CHF 90–230
- Website
- airfrance.com
Flights from Florence Peretola Airport to Basel via Paris Charles de Gaulle
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 65–370
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 24–65
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Spiez
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- CHF 45–90
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 60–90
- 2nd Class
- CHF 45–65
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- CHF 24–65
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 45–65
- 2nd Class
- CHF 24–35
- Phone
- +41 58 327 32 71
- Website
- bls.ch
Train from Domodossola to Muelenen
- Ave. Duration
- 1h 37m
- Frequency
- Hourly
- Estimated price
- CHF 18–25
- Website
- https://www.bls.ch/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Zürich Flughafen to Bern
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- CHF 35–60
- Website
- https://www.sbb.ch/en
Train from Bern to Interlaken West
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- CHF 30–34
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Interlaken West
- Ave. Duration
- 1h 55m
- Frequency
- Every 2 hours
- Estimated price
- CHF 35–65
- Website
- https://www.sbb.ch/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- CHF 10
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- CHF 8–9
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 28–75
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 14–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- CHF 21–45
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- CHF 9–13
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Interlaken West
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- CHF 12–16
- Schedules at
- sbb-deutschland.de
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena Central Train Station to Milan Malpensa Airport 1 P13
- Ave. Duration
- 6h 55m
- Frequency
- 6 times a week
- Estimated price
- CHF 24–40
- Website
- https://www.itabus.it/en/home
Bus from Siena Central Train Station to Zurich Ausstellungsstrasse
- Ave. Duration
- 11h 30m
- Frequency
- Once daily
- Estimated price
- CHF 27–60
- Website
- https://www.itabus.it/en/home
- Phone
- +39 0322 844 862
- comazzi@comazzibus.com
- Website
- comazzibus.com
Bus from Aeroporto Malpensa - Terminal 1 to Domodossola - Stazione Ferroviaria
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- CHF 8
- Website
- https://www.comazzibus.com/eng/index.php
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena Central Train Station to Zurich Ausstellungsstrasse
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- CHF 40–65
- Website
- https://www.flixbus.co.uk
- Phone
- +41 44 552 0807
- contact@shuttler.ch
- Website
- shuttler.ch
Bus from Zürich HB Schweizerhof to Interlaken Sonnenhof
- Ave. Duration
- 1h 57m
- Frequency
- 5 times a week
- Estimated price
- CHF 22–26
- Website
- https://shuttler.ch/
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 incredible day trips from Florence by train
Read the travel guide
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
More Questions & Answers
Siena to Interlaken bus services, operated by Itabus S.p.A., arrive at Zurich Ausstellungsstrasse station.
Siena to Interlaken train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Interlaken is 622 km. It takes approximately 6h 46m to drive from Siena to Interlaken.
Book your Siena to Interlaken train tickets online with Omio.
There are 1822+ hotels available in Interlaken.














































