There are 9 ways to get from Siena to Frankfurt am Main by bus, plane, train, car or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus to Florence, fly  •  5 h 38 min

  1. Take the bus from Siena-Via Tozzi to Leopolda
  2. Fly from Florence (FLR) to Frankfurt (FRA) FLR - FRA

$103 - $367

Cheapest option

Bus  •  16 h 32 min

  1. Take the bus from Siena to Firenze Marozzi
  2. Take the bus from Florence, Florence to Frankfurt, Frankfurt central station N537 / ...

$67 - $116

7 alternative options

Train, train to Pisa, fly  •  5 h 48 min

  1. Take the train from Siena to Empoli
  2. Take the train from Empoli to Pisa C.Le
  3. Fly from Pisa (PSA) to Frankfurt (FRA) PSA - FRA

$94 - $736

Train, train to Bologna, fly  •  6 h 46 min

  1. Take the train from Siena to Firenze Smn
  2. Take the train from Firenze S.Maria Novella to Bologna C.Le
  3. Fly from Bologna (BLQ) to Frankfurt (FRA) BLQ - FRA

$106 - $397

Train  •  12 h 8 min

  1. Take the train from Siena to Firenze Smn Reg / ...
  2. Take the train from Firenze S.Maria Novella to Milano Centrale Fr / ...
  3. Take the train from Milano Centrale to Frankfurt(Main)Hbf Ece / ...

$136 - $341

Train via Basel SBB  •  12 h 22 min

  1. Take the train from Siena to Firenze Smn Reg / ...
  2. Take the train from Firenze S.Maria Novella to Milano Centrale Fr / ...
  3. Take the train from Milano Centrale to Basel SBB Ece / ...
  4. Take the train from Basel SBB to Frankfurt(Main)Hbf Ice / ...

$191 - $331

Drive, cartrain  •  13 h 17 min

  1. Drive from Siena to Verona Porta Nuova
  2. Take the cartrain from Verona Porta Nuova to Frankfurt(Main)Süd UEX 1384

$109 - $204

Bus, cartrain  •  21 h 18 min

  1. Take the bus from Rinaldo Franci to Firenze Autostazione 131
  2. Take the bus from Firenze Autostazione to Verona Stazione Verona Porta Nuova
  3. Take the cartrain from Verona Porta Nuova to Frankfurt(Main)Süd

$111 - $203

Drive  •  10 h 1 min

  1. Drive from Siena to Frankfurt am Main 649.5 miles

$150 - $230

Questions & Answers

No, there is no direct bus from Siena to Frankfurt am Main station. However, there are services departing from Siena and arriving at Frankfurt, Frankfurt central station via Nenni 03 and Florence, Florence. The journey, including transfers, takes approximately 16 h 32 min.

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No, there is no direct train from Siena to Frankfurt am Main. However, there are services departing from Siena and arriving at Frankfurt(Main)Hbf via Firenze S.Maria Novella and Milano Centrale. The journey, including transfers, takes approximately 12 h 8 min.

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The distance between Siena and Frankfurt am Main is 782 km. The road distance is 1039.2 km.

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The best way to get from Siena to Frankfurt am Main without a car is to train which takes 12 h 8 min and costs .

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It takes approximately 5 h 38 min to get from Siena to Frankfurt am Main, including transfers.

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Siena to Frankfurt am Main bus services, operated by Marozzi VT, depart from Siena station.

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Siena to Frankfurt am Main train services, operated by Trenitalia, depart from Siena station.

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The best way to get from Siena to Frankfurt am Main is to train which takes 12 h 8 min and costs . Alternatively, you can bus, which costs and takes 16 h 32 min.

Mode details

The quickest flight from Florence Airport to Frankfurt Airport is the direct flight which takes 1 h 35 min.

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Siena to Frankfurt am Main bus services, operated by FlixBus, arrive at Frankfurt, Frankfurt central station.

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Map of how to get from Siena to Frankfurt am Main.
Launch map view
  • Distance: 488.8 miles
  • Duration: 5 h 38 min

What companies run services between Siena, Italy and Frankfurt am Main, Germany?

You can take a train from Siena to Frankfurt am Main via Firenze Smn, Firenze S.Maria Novella, and Milano Centrale in around 12 h 8 min. Alternatively, you can take a bus from Siena to Frankfurt am Main via Firenze, Nenni 03, Sette Regole, and Florence, Florence in around 16 h 32 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Florence to Frankfurt
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$180 - $600
Flights from Florence to Frankfurt via Munich
Ave. Duration
3 h 18 min
When
Every day
Estimated price
$120 - $250
Flights from Pisa to Frankfurt via Munich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$330 - $1,300
Flights from Bologna to Frankfurt
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$160 - $550
Flights from Bologna to Frankfurt via Munich
Ave. Duration
3 h 16 min
When
Every day
Estimated price
$120 - $260
Swiss
Website
swiss.com
Flights from Florence to Frankfurt via Zurich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$210 - $1,000
Alitalia
Website
alitalia.com
Flights from Florence to Frankfurt via Rome
Ave. Duration
4 h 5 min
When
Monday, Tuesday, Wednesday, Friday, Saturday and Sunday
Estimated price
$190 - $700
Ryanair
Website
ryanair.com
Flights from Pisa to Frankfurt
Ave. Duration
1 h 30 min
When
Wednesday, Thursday and Saturday
Estimated price
$26 - $180
Train operators
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Siena to Empoli
Ave. Duration
1 h 2 min
Frequency
Every 30 minutes
Estimated price
$5 - $12
Website
orario.trenitalia.com
1st Class
$9 - $12
Train from Empoli to Pisa C.Le
Ave. Duration
30 min
Frequency
Every 20 minutes
Estimated price
$3 - $9
Website
orario.trenitalia.com
1st Class
$7 - $9
Train from Siena to Firenze Smn
Ave. Duration
1 h 32 min
Frequency
Hourly
Estimated price
$7 - $16
Website
orario.trenitalia.com
1st Class
$13 - $16
Train from Firenze Smn to Bologna C.Le
Ave. Duration
1 h 27 min
Frequency
Once daily
Estimated price
$7 - $16
Website
orario.trenitalia.com
1st Class
$13 - $16
Train from Milano Centrale to Frankfurt(Main)Hbf
Ave. Duration
7 h 36 min
Frequency
Once daily
Estimated price
$150 - $270
Website
orario.trenitalia.com
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.Maria Novella to Bologna C.Le
Ave. Duration
35 min
Frequency
Every 30 minutes
Estimated price
$15 - $23
Website
orario.trenitalia.com
Train from Firenze S.Maria Novella to Milano Centrale
Ave. Duration
1 h 40 min
Frequency
Hourly
Estimated price
$35 - $55
Website
orario.trenitalia.com
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Firenze Santa Maria Novella Station to Bologna Centrale Station
Ave. Duration
39 min
Frequency
Hourly
Estimated price
$17 - $25
Website
italotreno.it
Train from Firenze Santa Maria Novella Station to Milano Centrale Station
Ave. Duration
2 h 3 min
Frequency
Hourly
Estimated price
$29 - $45
Website
italotreno.it
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Milano Centrale to Frankfurt(Main)Hbf
Ave. Duration
7 h 36 min
Frequency
Once daily
Estimated price
$100 - $140
Website
orario.trenitalia.com
Train from Milano Centrale to Basel SBB
Ave. Duration
4 h 6 min
Frequency
Every 4 hours
Estimated price
$80 - $140
Website
orario.trenitalia.com
Train from Basel Sbb to Frankfurt(Main)Hbf
Ave. Duration
3 h 21 min
Frequency
Once daily
Estimated price
$50 - $75
Website
orario.trenitalia.com
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Basel SBB to Frankfurt(Main)Hbf
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$75 - $120
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Urlaubs-Express
Phone
+49 (0) 221 800 20 820
Email
info@urlaubs-express.de
Website
urlaubs-express.de
Car train from Verona Porta Nuova to Frankfurt(Main)Süd
Ave. Duration
10 h 18 min
Frequency
Once a week
Estimated price
$65 - $140
Schedules at
urlaubs-express.de
Passenger
$68
Motorcycle
$115
Vehicle
$126
Bus operators
Tiemme Spa
Phone
+39.0565.260111
Email
segreteria@tiemmespa.it
Website
tiemmespa.it
Bus from Siena-Via Tozzi to Leopolda
Ave. Duration
1 h 14 min
Frequency
Hourly
Estimated price
$5 - $9
Schedules at
tiemmespa.it
Bus from Rinaldo Franci to Firenze Autostazione
Ave. Duration
1 h 15 min
Frequency
Hourly
Estimated price
$6 - $9
Schedules at
tiemmespa.it
Marozzi VT
Phone
080 579 0211
Email
info@marozzivt.it
Website
marozzivt.it
Bus from Siena to Firenze
Ave. Duration
1 h 10 min
Frequency
Every 30 minutes
Estimated price
$10 - $13
Schedules at
marozzivt.it
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Florence, Florence to Frankfurt, Frankfurt central station
Ave. Duration
14 h 5 min
Frequency
Twice daily
Estimated price
$55 - $100
Website
flixbus.co.uk

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More Questions & Answers

Siena to Frankfurt am Main train services, operated by Trenitalia, arrive at Frankfurt(Main)Hbf station.

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Yes, the driving distance between Siena to Frankfurt am Main is 1039 km. It takes approximately 10 h 1 min to drive from Siena to Frankfurt am Main.

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Swiss, Alitalia, Air Dolomiti and Lufthansa offer flights from Florence Airport to Frankfurt Airport.

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There are 676+ hotels available in Frankfurt am Main. Prices start at $56 USD per night.

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