There are 11 ways to get from Siena to Agrigento by car, plane, train, bus, train (Trenitalia), or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Pisa International Airport, fly to Palermo Airport, train
best- Drive from Siena to Pisa International Airport (PSA)car
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
6h 41m€66–220Bus via Rome
cheapest- Take the bus from Siena - p.zza Rosselli to Roma, Autostazione Tiburtinabus Siena
- Take the bus from Roma, Autostazione Tiburtina to Agrigento Piazzale Vittorio Emanuelebus
18h€45–70Train (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Agrigento Centraletrain Re
18h 9m€135–305Drive, ferry
- Drive from Siena to Civitavecchiacar
- Take the ferry from Civitavecchia to Palermoferry
- Drive from Palermo to Agrigentocar
18h 22m€92–155Bus to Florence Peretola Airport, fly to Palermo Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
7h 39m€88–193Bus to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
7h 53m€48–168Drive to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus
- Drive from Siena to Pisa International Airport (PSA)car
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
7h€68–205Drive to Pisa International Airport, fly to Trapani Airport, bus
- Drive from Siena to Pisa International Airport (PSA)car
- Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane PSA - TPS
- Take the bus from Trapani Birgi Airport to Agrigento - piazz.le Fratelli Rossellibus
7h 10m€66–368Bus to Perugia Sant'Egidio Airport, fly to Palermo Airport, train
- Take the bus from Siena to Perugiabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane PEG - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
9h 3m€65–281Bus
- Take the bus from Siena to Agrigentobus N528
18h 45m€80–140Train via Chiusi (Trenitalia)
- Take the train from Siena to Chiusi-Chianciano T.train Re
- Take the train from Chiusi-Chianciano T. to Roma Terminitrain Re
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Agrigento Centraletrain Re
19h 13m€123–264
Siena to Agrigento by bus
Questions & Answers
The cheapest way to get from Siena to Agrigento is to bus via Rome which costs €45 - €70 and takes 18h.
The fastest way to get from Siena to Agrigento is to drive and fly and train which takes 6h 41m and costs €65 - €220.
Yes, there is a direct bus departing from Siena and arriving at Agrigento. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
No, there is no direct train from Siena to Agrigento. However, there are services departing from Siena and arriving at Agrigento Centrale via Firenze S.M.N., Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 18h 9m.
The distance between Siena and Agrigento is 934 km.
The best way to get from Siena to Agrigento without a car is to bus via Rome which takes 18h and costs €45 - €70.
It takes approximately 6h 41m to get from Siena to Agrigento, including transfers.
Siena to Agrigento bus services, operated by Autolinee Federico, depart from Siena - p.zza Rosselli station.
Siena to Agrigento train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Agrigento is to bus via Rome which takes 18h and costs €45 - €70. Alternatively, you can train, which costs €130 - €310 and takes 18h 9m.
What companies run services between Siena, Italy and Agrigento, Italy?
You can take a bus from Siena - p.zza Rosselli to Agrigento Piazzale Vittorio Emanuele via Roma, Autostazione Tiburtina in around 18h. Alternatively, you can take a train from Siena to Agrigento Centrale via Firenze S.M.N., Roma Termini, and Termini Imerese in around 18h 9m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €28–150
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €40–160
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday
- Estimated price
- €40–160
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Tirana
- Ave. Duration
- 3h 54m
- When
- Tuesday and Friday
- Estimated price
- €40–160
Flights from Pisa International Airport to Trapani Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €40–330
Flights from Perugia Sant'Egidio Airport to Palermo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–190
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €70–150
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- €70–130
- Website
- volotea.com
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €40–130
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €70–150
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €27–150
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €29–130
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Aeroporto to Agrigento Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 3 times a day
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 4h 31m
- Frequency
- 4 times a day
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Termini Imerese to Agrigento Centrale
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Chiusi-Chianciano T.
- Ave. Duration
- 1h 28m
- Frequency
- Every 2 hours
- Estimated price
- €11–18
- Website
- https://www.trenitalia.com/en.html
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- €18–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 42m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €26–60
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 11h 7m
- Frequency
- Once daily
- Estimated price
- €85–190
- Website
- https://www.trenitalia.com/en.html
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 30m
- Frequency
- 3 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
Bus from Siena - p.zza Rosselli to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- €10–15
- Schedules at
- autolineefederico.it
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Agrigento Piazzale Vittorio Emanuele
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- €35–55
- Schedules at
- autoservizisalemi.it
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–16
- Website
- https://saistrasporti.it/en-US
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 19m
- Frequency
- Twice daily
- Estimated price
- €11–20
- Website
- https://www.flixbus.co.uk
Bus from Siena to Perugia
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €7–13
- Website
- https://www.flixbus.co.uk
Bus from Siena to Agrigento
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0922.20414
- info@autolineelumia.it
- Website
- autolineelumia.com
Bus from Trapani Birgi Airport to Agrigento - piazz.le Fratelli Rosselli
- Ave. Duration
- 3h
- Frequency
- 5 times a day
- Estimated price
- €9–13
- Schedules at
- autolineelumia.com
- .
- €9–13
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Ferry from Civitavecchia to Palermo
- Ave. Duration
- 13h 45m
- Frequency
- Once a week
- Estimated price
- €45–85
- Website
- https://www.gnv.it/en
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More Questions & Answers
Siena to Agrigento bus services, operated by Autolinee Federico, arrive at Roma, Autostazione Tiburtina station.
Siena to Agrigento train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Siena to Agrigento train tickets online with Omio.
Book your Siena to Agrigento bus tickets online with Omio.
There are 506+ hotels available in Agrigento.































