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How to get fromSiena to Agrigentoby train, plane, train (Trenitalia), bus, car or ferry

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There are 10 ways to get from Siena to Agrigento by train, plane, train (Trenitalia), bus, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Palermo Airport, train

    best
    1. Take the train from Siena to Firenze S.M.N.train
    2. Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)planeFLR - PMO
    3. Take the train from Palermo Aeroporto to Agrigento Centraletrain
    7h 57m
    €74–218
  2. Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus

    cheapest
    1. Take the train from Siena to Firenze S.M.N.train
    2. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)planeFLR - CTA
    3. Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
    8h 12m
    €53–198
  3. Train

    1. Take the train from Siena to Firenze S.M.N.trainRe
    2. Take the train from Florence Santa Maria Novella to Roma Terminitrain
    3. Take the train from Roma Termini to Termini ImeresetrainIc
    4. Take the train from Termini Imerese to Agrigento CentraletrainRe
    17h 59m
    €108–186
  4. Bus

    1. Take the bus from Siena to AgrigentobusN528
    18h 45m
    €70–100
  5. Drive, ferry

    1. Drive from Siena to Villa San Giovannicar
    2. Take the ferry from Villa San Giovanni to Messina Marittimaferry
    3. Drive from Messina Marittima to Agrigentocar
    12h 16m
    €171–256
  6. Train, train to Pisa International Airport, fly to Palermo Airport

    1. Take the train from Siena to Empolitrain
    2. Take the train from Empoli to Pisa Centraletrain
    3. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)planePSA - PMO
    4. Take the train from Palermo Aeroporto to Agrigento Centraletrain
    8h 5m
    €89–236
  7. Bus to Perugia Sant'Egidio Airport, fly to Palermo Airport, train

    1. Take the bus from Siena to Perugiabus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)planePEG - PMO
    3. Take the train from Palermo Aeroporto to Agrigento Centraletrain
    7h 27m
    €106–385
  8. Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus

    1. Take the train from Siena to Empolitrain
    2. Take the train from Empoli to Pisa Centraletrain
    3. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)planePSA - CTA
    4. Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
    8h 25m
    €73–216
  9. Train via Chiusi

    1. Take the train from Siena to Chiusi-Chianciano T.trainRe
    2. Take the train from Chiusi-Chianciano T. to Roma TerminitrainRe
    3. Take the train from Roma Termini to Termini ImeresetrainIc
    4. Take the train from Termini Imerese to Agrigento CentraletrainRe
    19h 10m
    €93–152
  10. Bus via Florence

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus131R / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Porto Empedocle Bus StationbusAutoservizi Salemi S121 / ...
    19h 54m

Siena to Agrigento by train

Calendar7Weekly Trains
Duration17h 59mAverage Duration
Ticket€108Cheapest Price
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Questions & Answers

What companies run services between Siena, Italy and Agrigento, Italy?

You can take a train from Siena to Agrigento Centrale via Florence Santa Maria Novella, Roma Termini, and Termini Imerese in around 17h 59m. Alternatively, FlixBus operates a bus from Siena to Agrigento once daily. Tickets cost €70–100 and the journey takes 18h 45m.

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