There are 10 ways to get from Siena to Agrigento by train, plane, train (Trenitalia), bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Palermo Airport, train
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
7h 58m€72–218Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus
cheapest- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
8h 12m€50–198Train
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Roma Terminitrain
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Agrigento Centraletrain Re
18h 19m€118–171Bus
- Take the bus from Siena to Agrigentobus N528
18h 45m€85–120Drive, ferry
- Drive from Siena to Villa San Giovannicar
- Take the ferry from Villa San Giovanni to Messina Marittimaferry
- Drive from Messina Marittima to Agrigentocar
11h 39m€176–264Train, train to Pisa International Airport, fly to Palermo Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
8h 7m€90–266Bus to Perugia Sant'Egidio Airport, fly to Palermo Airport, train
- Take the bus from Siena to Perugiabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane PEG - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
7h 28m€75–371Train, train to Bologna Guglielmo Marconi Airport, fly to Palermo Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Florence Santa Maria Novella to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane BLQ - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
8h 54m€85–280Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
8h 26m€73–226Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Porto Empedocle Bus Stationbus Autoservizi Salemi S121 / ...
19h 54m
Siena to Agrigento by train
Questions & Answers
The cheapest way to get from Siena to Agrigento is to bus which costs €85 - €120 and takes 18h 45m.
The fastest way to get from Siena to Agrigento is to bus and fly and train which takes 7h 28m and costs €75 - €380.
Yes, there is a direct bus departing from Siena and arriving at Agrigento. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
No, there is no direct train from Siena to Agrigento. However, there are services departing from Siena and arriving at Agrigento Centrale via Florence Santa Maria Novella, Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 18h 19m.
The distance between Siena and Agrigento is 912 km.
The best way to get from Siena to Agrigento without a car is to train which takes 18h 19m and costs €110 - €180.
It takes approximately 7h 58m to get from Siena to Agrigento, including transfers.
Siena to Agrigento bus services, operated by FlixBus, depart from Siena station.
Siena to Agrigento train services, operated by Trenitalia S.p.A., depart from Siena station.
The best way to get from Siena to Agrigento is to train which takes 18h 19m and costs €110 - €180. Alternatively, you can bus, which costs €85 - €120 and takes 18h 45m.
What companies run services between Siena, Italy and Agrigento, Italy?
You can take a train from Siena to Agrigento Centrale via Florence Santa Maria Novella, Roma Termini, and Termini Imerese in around 18h 19m. Alternatively, FlixBus operates a bus from Siena to Agrigento once daily. Tickets cost €85–120 and the journey takes 18h 45m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €55–210
Flights from Perugia Sant'Egidio Airport to Palermo Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €35–250
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €35–230
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Friday
- Estimated price
- €35–230
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €45–170
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- €70–180
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €70–150
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €45–160
- Website
- volotea.com
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday and Friday
- Estimated price
- €30–170
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €28–160
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €29–200
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Aeroporto to Agrigento Centrale
- Ave. Duration
- 2h 36m
- Frequency
- Twice daily
- Estimated price
- €10–16
- Website
- https://www.trenitalia.com/en.html
Train from Termini Imerese to Agrigento Centrale
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €22–50
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 11h 8m
- Frequency
- Once daily
- Estimated price
- €75–100
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Agrigento
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €85–120
- Website
- https://www.flixbus.co.uk
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 19m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Website
- https://www.flixbus.co.uk
Bus from Siena to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €6–11
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–16
- Website
- https://saistrasporti.it/en-US
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Porto Empedocle Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- 4 times a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Villa San Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
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More Questions & Answers
Siena to Agrigento bus services, operated by FlixBus, arrive at Agrigento station.
Siena to Agrigento train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Book your Siena to Agrigento train tickets online with Omio.
Book your Siena to Agrigento bus tickets online with Omio and FlixBus.
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