There are 10 ways to get from Siena to Agrigento by train, plane, bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Palermo Airport, train
best- Take the train from Siena to Firenze Rifreditrain
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
7h 54m€88–225Bus via Florence
cheapest- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Porto Empedocle Bus Stationbus Autoservizi Salemi S121 / ...
19h 54m€52–78Bus, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Agrigento Bassatrain Re
18h 12m€129–291Drive, ferry
- Drive from Siena to Civitavecchiacar
- Take the ferry from Civitavecchia to Palermoferry
- Drive from Palermo to Agrigentocar
18h 21m€94–151Bus
- Take the bus from Siena to Agrigentobus N528
18h 45m€85–150Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Firenze Rifreditrain
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
8h 8m€58–190Train, train to Pisa International Airport, fly to Palermo Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
8h 12m€65–205Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus
8h 31m€64–180Train, train to Pisa International Airport, fly to Trapani Airport, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane PSA - TPS
- Take the bus from Trapani Birgi Airport to Agrigento - piazz.le Fratelli Rossellibus
8h 41m€62–223Bus to Perugia Sant'Egidio Airport, fly to Palermo Airport, train
- Take the bus from Siena to Perugiabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane PEG - PMO
- Take the train from Palermo Aeroporto to Agrigento Centraletrain
9h 3m€76–222
Siena to Agrigento by bus and train
Questions & Answers
The cheapest way to get from Siena to Agrigento is to bus via Florence which costs €50 - €80 and takes 19h 54m.
The fastest way to get from Siena to Agrigento is to train and fly which takes 7h 54m and costs €85 - €230.
Yes, there is a direct bus departing from Siena and arriving at Agrigento. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
The distance between Siena and Agrigento is 909 km.
The best way to get from Siena to Agrigento without a car is to bus and train which takes 18h 12m and costs €120 - €300.
It takes approximately 7h 54m to get from Siena to Agrigento, including transfers.
Siena to Agrigento bus services, operated by FlixBus, depart from Siena station.
Siena to Agrigento bus services, operated by FlixBus, arrive at Agrigento station.
Book your Siena to Agrigento bus tickets online with Omio and FlixBus.
There are 1311+ hotels available in Agrigento.
What companies run services between Siena, Italy and Agrigento, Italy?
FlixBus operates a bus from Siena to Agrigento once daily. Tickets cost €85–150 and the journey takes 18h 45m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €25–140
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–120
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday
- Estimated price
- €35–120
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €35–120
Flights from Pisa International Airport to Trapani Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–180
Flights from Perugia Sant'Egidio Airport to Palermo Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–160
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- €80–170
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €80–140
- Website
- volotea.com
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €45–160
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €80–170
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €28–140
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- €80–140
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Friday, and Sunday
- Estimated price
- €50–150
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze Rifredi
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Aeroporto to Agrigento Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 3 times a day
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 4h 31m
- Frequency
- 4 times a day
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Termini Imerese to Agrigento Bassa
- Ave. Duration
- 1h 34m
- Frequency
- Every 2 hours
- Estimated price
- €12–20
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €27–60
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 11h 8m
- Frequency
- Once daily
- Estimated price
- €85–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Siena to Agrigento
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €85–150
- Website
- https://www.flixbus.co.uk
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 19m
- Frequency
- Twice daily
- Estimated price
- €12–20
- Website
- https://www.flixbus.co.uk
Bus from Siena to Perugia
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €7–13
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rosselli
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–16
- Website
- https://saistrasporti.it/en-US
- Phone
- +39 0922.20414
- info@autolineelumia.it
- Website
- autolineelumia.com
Bus from Trapani Birgi Airport to Agrigento - piazz.le Fratelli Rosselli
- Ave. Duration
- 3h
- Frequency
- 5 times a day
- Estimated price
- €9–13
- Schedules at
- autolineelumia.com
- .
- €9–13
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Porto Empedocle Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- 4 times a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Ferry from Civitavecchia to Palermo
- Ave. Duration
- 13h 45m
- Frequency
- Once a week
- Estimated price
- €45–80
- Website
- https://www.gnv.it/en
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