There are 8 ways to get from Shepherdstown to Buffalo by taxi, plane, bus (Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Washington Dulles International Airport, fly to Buffalo Niagara International Airport
best- Take the taxi from Shepherdstown to Harmony Park and Ridetaxi
- Fly from Washington Dulles International Airport (IAD) to Buffalo Niagara International Airport (BUF)plane IAD - BUF
4h 40m$149–615Drive 297.8 mi
cheapest- Drive from Shepherdstown to Buffalocar 297.8 mi
7h 5m$55–79Bus (Greyhound)
- Take the bus from Frederick Bus Station to Cleveland Bus Stationbus Greyhound US0164
- Take the bus from Cleveland Bus Station to Buffalobus Greyhound US0171 / ...
14h 10m$115–197Train (Amtrak)
- Take the train from Martinsburg Amtrak Station to Cleveland Amtraktrain Floridian
- Take the train from Cleveland Amtrak to Buffalo Depew Stationtrain Lake Shore Limited
14h 54m$197–519Train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport
- Take the train from DUFFIELDS W VA MARC eb to SILVER SPRING MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane DCA - BUF
5h 19m$153–918Train, train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport
- Take the train from DUFFIELDS W VA MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
5h 57m$106–1,210Taxi to Washington Dulles International Airport, fly to Rochester, bus
- Take the taxi from Shepherdstown to Harmony Park and Ridetaxi
- Fly from Washington Dulles International Airport (IAD) to Rochester (ROC)plane IAD - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 16m$170–609Train, bus
- Take the train from Martinsburg Amtrak Station to Pittsburgh Amtrak Stationtrain Floridian
- Take the bus from Pittsburgh, Pa to Buffalo, Nybus 510
15h 7m$140–359
Washington Dulles International Airport (IAD) to Buffalo Niagara International Airport (BUF) flights
Questions & Answers
The cheapest way to get from Shepherdstown to Buffalo is to drive which costs $50 - $80 and takes 7h 5m.
The fastest way to get from Shepherdstown to Buffalo is to taxi and fly which takes 4h 40m and costs $140 - $650.
No, there is no direct bus from Shepherdstown to Buffalo. However, there are services departing from Route 478 at Route 180 and arriving at Buffalo via Frederick Bus Station and Cleveland Bus Station. The journey, including transfers, takes approximately 14h 10m.
No, there is no direct train from Shepherdstown station to Buffalo. However, there are services departing from Martinsburg Amtrak Station and arriving at Buffalo via Cleveland Amtrak and Buffalo Depew Station. The journey, including transfers, takes approximately 14h 54m.
The distance between Shepherdstown and Buffalo is 349 miles. The road distance is 299.6 miles.
The best way to get from Shepherdstown to Buffalo without a car is to bus which takes 14h 10m and costs $110 - $200.
It takes approximately 4h 40m to get from Shepherdstown to Buffalo, including transfers.
Shepherdstown to Buffalo bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Shepherdstown to Buffalo train services, operated by Amtrak, depart from Martinsburg Amtrak Station.
The best way to get from Shepherdstown to Buffalo is to bus which takes 14h 10m and costs $110 - $200. Alternatively, you can train, which costs $190 - $550 and takes 14h 54m.
What companies run services between Shepherdstown, WV, USA and Buffalo, NY, USA?
You can take a vehicle from Shepherdstown to Buffalo via Route 478 at Route 180, East Street at Transit Center, Frederick Bus Station, and Cleveland Bus Station in around 14h 10m. Alternatively, you can take a vehicle from Shepherdstown to Buffalo via Martinsburg Amtrak Station, Cleveland Amtrak, and Buffalo Depew Station in around 14h 54m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $85–600
- Website
- united.com
Flights from Washington Dulles International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $75–490
Flights from Washington Dulles International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $70–470
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $130–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Martinsburg Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 9h 16m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- https://www.amtrak.com/home.html
Train from Cleveland Amtrak to Buffalo Depew Station
- Ave. Duration
- 3h 3m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- https://www.amtrak.com/home.html
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $9–19
- Website
- https://www.amtrak.com/home.html
Train from Martinsburg Amtrak Station to Pittsburgh Amtrak Station
- Ave. Duration
- 6h 3m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.amtrak.com/home.html
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from DUFFIELDS W VA MARC eb to SILVER SPRING MARC eb
- Ave. Duration
- 1h 20m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
Train from DUFFIELDS W VA MARC eb to Washington Union Station
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- $2–13
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–13
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- $2–9
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–9
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- $6–550
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $6–440
- First Class
- $100–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Frederick Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Buffalo
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–21
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $10–18
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Pittsburgh, Pa to Buffalo, Ny
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $45–190
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $45–180
- Flexible
- $80–190
- Ave. Duration
- 45 min
- Estimated price
- $65–85
Bonnie's Transportation
- Phone
- +1 240-527-5377
Yellow Cab Hagerstown
- Phone
- +1-301-547-3845
Bonnie's Transportation
- Phone
- +1 240-527-5377
Yellow Cab Hagerstown
- Phone
- +1-301-547-3845
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More Questions & Answers
Shepherdstown to Buffalo bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Shepherdstown to Buffalo train services, operated by Amtrak, arrive at Cleveland Amtrak station.
Yes, the driving distance between Shepherdstown to Buffalo is 300 miles. It takes approximately 7h 5m to drive from Shepherdstown to Buffalo.
There are 193+ hotels available in Buffalo.











