There are 5 ways to get from Setúbal to Lyon by bus, plane, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly
best- Take the bus from Interface de Transportes de Setúbal P1 to Gare do Oriente 21-Cbus
- Fly from Lisbon-Portela Airport (LIS) to Lyon–Saint Exupéry Airport (LYS)plane LIS - LYS
5h 58m€81–339Bus, train via Madrid
- Take the bus from Setúbal to Badajozbus
- Take the train from Badajoz to Madrid-Puerta de Atocha-Almudena Grandestrain Alv
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
17h 22m€195–379Bus
- Take the bus from Interface de Transportes de Setúbal P1 to Gare do Oriente 21-Cbus 4720 / ...
- Take the bus from Lisbon - Oriente to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
26h 27m€134–255Drive 1,685.6 km
- Drive from Setúbal to Lyoncar 1,685.6 km
16h 43m€272–393Bus, train
- Take the bus from Interface de Transportes de Setúbal to Avignonbus
- Take the train from Avignon Centre to Lyon Part Dieutrain Ter
27h 56m€174–289
Setúbal to Lyon by bus
Comparing Your Travel Options
The cheapest way to get from Setúbal to Lyon is to bus and fly which costs €80 - €340 and takes 5h 58m.
The fastest way to get from Setúbal to Lyon is to bus and fly which takes 5h 58m and costs €80 - €340.
No, there is no direct bus from Setúbal to Lyon station. However, there are services departing from Interface de Transportes de Setúbal P1 and arriving at Lyon - Gerland Bus Station via Lisbon - Oriente. The journey, including transfers, takes approximately 26h 27m.
The distance between Setúbal and Lyon is 1469 km. The road distance is 1685.6 km.
The best way to get from Setúbal to Lyon without a car is to bus and train via Madrid which takes 17h 22m and costs €190 - €380.
It takes approximately 5h 58m to get from Setúbal to Lyon, including transfers.
Setúbal to Lyon bus services, operated by Carris Metropolitana, depart from Interface de Transportes de Setúbal P1 station.
Setúbal to Lyon bus services, operated by Carris Metropolitana, arrive at Gare do Oriente 21-C station.
Lyon is 1h ahead of Setúbal. It is currently 3:54 AM in Setúbal and 4:54 AM in Lyon.
Yes, the driving distance between Setúbal to Lyon is 1686 km. It takes approximately 16h 43m to drive from Setúbal to Lyon.
What companies run services between Setúbal, Portugal and Lyon, France?
You can take a bus from Interface de Transportes de Setúbal P1 to Lyon - Gerland Bus Station via Gare do Oriente 21-C and Lisbon - Oriente in around 26h 27m.
- Website
- easyjet.com
Flights from Lisbon-Portela Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Friday, Wednesday, Thursday, Sunday, and Tuesday
- Estimated price
- €50–250
Flights from Lisbon-Portela Airport to Lyon–Saint Exupéry Airport via Bordeaux
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, and Thursday
- Estimated price
- €50–250
- Website
- flytap.com
Flights from Lisbon-Portela Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €65–240
- Website
- iberia.com
Flights from Lisbon-Portela Airport to Lyon–Saint Exupéry Airport via Madrid
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- €65–230
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Badajoz to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a day
- Estimated price
- €55–85
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €85–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 27m
- Frequency
- Hourly
- Estimated price
- €45–80
- Website
- Ouigo
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Centre to Lyon Part Dieu
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- €40–70
- Website
- Oui.SNCF
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Avignon Centre to Lyon Part Dieu
- Ave. Duration
- 2h 31m
- Frequency
- Every 3 hours
- Estimated price
- €60–85
- Website
- Zou! Lignes Express Régionales
Bus from Interface de Transportes de Setúbal P1 to Gare do Oriente 21-C
- Ave. Duration
- 42 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Interface de Transportes de Setúbal P1 to Gare do Oriente 21-C
- Ave. Duration
- 42 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Setúbal to Badajoz
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €14–24
- Website
- BlaBlaCar Bus
Bus from Lisbon - Oriente to Lyon - Gerland Bus Station
- Ave. Duration
- 24h 45m
- Frequency
- Once daily
- Estimated price
- €130–230
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Lisbon - Oriente to Lyon - Gerland Bus Station
- Ave. Duration
- 25h 10m
- Frequency
- Twice daily
- Estimated price
- €160–250
- Website
- Flixbus
- Phone
- +34 910 207 007
- Website
- alsa.es
Bus from Interface de Transportes de Setúbal to Avignon
- Ave. Duration
- 25h
- Frequency
- Once daily
- Estimated price
- €130–210
- Schedules at
- alsa.es
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in Spain: A guide to Renfe
Read the travel guide
What are the different types of Renfe trains in Spain?
Read the travel guide
Booking & Getting There
Book your Setúbal to Lyon bus tickets online with Omio.
There are 3927+ hotels available in Lyon.


































