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How to get fromSeguin to St. Louisby taxi, plane, bus (Flixbus, Greyhound), train (Amtrak), car or bus

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There are 5 ways to get from Seguin to St. Louis by taxi, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to San Antonio International Airport, fly

    best
    1. Take the taxi from Seguin to San-Antonio-Airport-SATtaxi taxi
    2. Fly from San Antonio International Airport (SAT) to Lambert–St. Louis International Airport (STL)plane plane SAT - STL
    3h 33m
    $261–942

  2. Drive 875.6 mi

    cheapest
    1. Drive from Seguin to St. Louiscar car 875.6 mi
    14h 28m
    $160–231

  3. Bus

    1. Take the bus from San Marcos to Dallas Bus Stationbus bus FlixBus US1164
    2. Take the bus from Dallas Bus Station to St Louis Bus Stationbus bus Greyhound US0136
    21h 33m
    $176–346

  4. Train (Amtrak)

    1. Take the train from San Marcos Amtrak to St. Louistrain train Texas Eagle
    23h 38m
    $193–376

  5. Bus to Austin-Bergstrom International Airport, fly

    1. Take the bus from San Marcos - Premium Outlets to Austinbus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Lambert–St. Louis International Airport (STL)plane plane AUS - STL
    5h 49m
    $261–991

San Antonio International Airport (SAT) to Lambert–St. Louis International Airport (STL) flights

Calendar46Weekly Planes
Duration3h 39mAverage Duration
Ticket$145Cheapest Price
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Questions & Answers

What companies run services between Seguin, TX, USA and St. Louis, MO, USA?

You can take a vehicle from Seguin to St Louis Bus Station via San Marcos and Dallas Bus Station in around 21h 33m. Alternatively, Amtrak operates a train from San Marcos Amtrak to St. Louis once daily. Tickets cost $120–290 and the journey takes 23h 10m.

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