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How to get fromSeffner to Chicagoby bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

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There are 7 ways to get from Seffner to Chicago by bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 38 bus, line 32 bus to Tampa, fly to Chicago Midway International Airport

    best
    1. Take the bus from M L King Jr Blvd @ Parsons Ave to Netpark Transfer Centerbus bus
    2. Take the bus from Netpark Transfer Center to Airport Rental Car Centerbus bus
    3. Fly from Tampa (TPA) to Chicago Midway International Airport (MDW)plane plane TPA - MDW
    6h 6m
    $108–411

  2. Fly Tampa to Chicago O'Hare International Airport

    cheapest
    1. Fly from Tampa (TPA) to Chicago O'Hare International Airport (ORD)plane plane TPA - ORD
    6h 35m
    $93–291

  3. Bus

    1. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus FlixBus N2467
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    28h 30m
    $194–334

  4. Train (Amtrak)

    1. Take the train from Tampa to Chicago Union Stationtrain train Floridian
    41h 13m
    $985–1,641

  5. Drive  1,123.6 mi

    1. Drive from Seffner to Chicagocar car 1,123.6 mi
    19h 55m
    $192–278

  6. Bus to Sarasota–Bradenton International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Chicago Midway International Airport (MDW)plane plane SRQ - MDW
    8h 43m
    $111–506

  7. Fly Tampa to General Mitchell International Airport, train

    1. Fly from Tampa (TPA) to General Mitchell International Airport (MKE)plane plane TPA - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 44m
    $703–1,195

Seffner to Chicago by bus

Calendar10Weekly Buses
Duration28h 30mAverage Duration
Ticket$194Cheapest Price
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Comparing Your Travel Options

Map of how to get from Seffner to Chicago.ExpandLaunch map view
  • Distance: 1,031.4 mi
  • Duration: 6h 6m

What companies run services between Seffner, FL, USA and Chicago, IL, USA?

You can take a bus from M L King Jr Blvd @ Parsons Ave to Chicago Bus Station via Netpark Transfer Center, Tampa Bus Station, and Atlanta Bus Station in around 28h 30m. Alternatively, Amtrak operates a train from Tampa to Chicago Union Station once daily. Tickets cost $950–1,600 and the journey takes 40h 56m.

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Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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