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How to get fromSeffner to Chicagoby bus, plane, bus (Amtrak, Flixbus, Greyhound), train (Amtrak), car, or train

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There are 7 ways to get from Seffner to Chicago by bus, plane, bus (Amtrak, Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 38 bus, line 32 bus to Tampa, fly to Chicago Midway International Airport

    best
    1. Take the bus from M L King Jr Blvd @ Parsons Ave to Netpark Transfer Centerbus bus
    2. Take the bus from Netpark Transfer Center to Airport Rental Car Facilitybus bus
    3. Fly from Tampa (TPA) to Chicago Midway International Airport (MDW)plane plane TPA - MDW
    6h
    $103–471

  2. Bus

    1. Take the bus from Lakeland to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    31h 55m
    $327–542

  3. Train (Amtrak)

    1. Take the train from Tampa to Chicago Union Stationtrain train Floridian
    41h 13m
    $585–1,241

  4. Drive 1,125.1 mi

    1. Drive from Seffner to Chicagocar car 1,125.1 mi
    19h 55m
    $206–297

  5. Fly Tampa to Chicago O'Hare International Airport

    1. Fly from Tampa (TPA) to Chicago O'Hare International Airport (ORD)plane plane TPA - ORD
    6h 37m
    $158–561

  6. Fly Tampa to General Mitchell International Airport, train

    1. Fly from Tampa (TPA) to General Mitchell International Airport (MKE)plane plane TPA - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 34m
    $185–825

  7. Bus to Sarasota–Bradenton International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Chicago Midway International Airport (MDW)plane plane SRQ - MDW
    8h 54m
    $146–627

Tampa (TPA) to Chicago Midway International Airport (MDW) flights

Calendar50Weekly Planes
Duration3h 10mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from Seffner to Chicago.ExpandLaunch map view
  • Distance: 1,030.5 mi
  • Duration: 6h

What companies run services between Seffner, FL, USA and Chicago, IL, USA?

You can take a vehicle from Seffner to Chicago Bus Station via Lakeland, Jacksonville, Amtrak Station, JRTC Bay H, Jacksonville, and Atlanta Bus Station in around 31h 55m. Alternatively, Amtrak operates a train from Tampa to Chicago Union Station once daily. Tickets cost $550–1,200 and the journey takes 40h 56m.

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