From Pioneer Sq Stn & 3rd Av - James - Bay C tram to Seattle airport, fly to Spokane airport, then line 60 bus to Spokane. 3 h 9 min $164. From Seattle, WA bus to Spokane, WA. 5 h 39 min $55. From Seattle King Street Station Amtrak train to Spokane Amtrak. 8 h $104. From Seattle drive to Spokane. 4 h 36 min $33.