There are 8 ways to get from Scranton to Lexington by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Wilkes-Barre/Scranton International Airport to Blue Grass Airport
best- Fly from Wilkes-Barre/Scranton International Airport (AVP) to Blue Grass Airport (LEX)AVP - LEX
6h 51m$224–1,051Drive 638.5 mi
cheapest- Drive from Scranton to Lexington638.5 mi
11h 13m$117–169Bus via Buffalo
- Take the bus from Scranton to Buffalo
- Take the bus from Buffalo, NY to Cincinnati, OH
- Take the bus from Cincinnati Bus Station to Lexington Bus Stop
19h 32m$131–240Bus, train
- Take the bus from Scranton, PA to Philadelphia 30th St Station201 / ...
- Take the train from 30th Street Station to Indianapolis
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
30h 2m$240–730Bus to Newark Liberty International Airport, fly to Louisville International Airport, drive
- Take the bus from Scranton to Newark Penn Station
- Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)EWR - SDF
- Drive from Louisville International Airport (SDF) to Lexington
7h 13m$166–488Bus to Laguardia Airport, fly to Blue Grass Airport
- Take the bus from Scranton, PA to Port Authority Bus Terminal
- Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)LGA - LEX
9h 8m$161–885Bus, train via Toledo
- Take the bus from Scranton to Syracuse Bus Station
- Take the train from Syracuse Regional Transportation Center to Toledo
- Take the bus from Toledo Bus Stop to Lexington Bus Stop
19h 50m$147–314Bus
- Take the bus from Scranton, PA to Harrisburg, PA
- Take the bus from Harrisburg Bus Station to Dayton Trotwood Bus Station
- Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stop
21h 42m$119–277
Wilkes-Barre/Scranton International Airport (AVP) to Blue Grass Airport (LEX) flights
Questions & Answers
The cheapest way to get from Scranton to Lexington is to drive which costs $110 - $170 and takes 11h 13m.
The fastest way to get from Scranton to Lexington is to fly which takes 6h 51m and costs $220 - $1,100.
The distance between Scranton and Lexington is 549 miles. The road distance is 642.2 miles.
The best way to get from Scranton to Lexington without a car is to bus via Buffalo which takes 19h 32m and costs $130 - $240.
It takes approximately 6h 51m to get from Scranton to Lexington, including transfers.
The best way to get from Scranton to Lexington is to fly which takes 6h 51m and costs $220 - $1,100. Alternatively, you can bus via Buffalo, which costs $130 - $240 and takes 19h 32m.
Yes, the driving distance between Scranton to Lexington is 642 miles. It takes approximately 11h 13m to drive from Scranton to Lexington.
There are 138+ hotels available in Lexington.
What companies run services between Scranton, PA, USA and Lexington, KY, USA?
American Airlines and United Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Blue Grass Airport (LEX) 5 times a day. Alternatively, you can take a bus from Scranton to Lexington via Buffalo, Buffalo, NY, Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 19h 32m.
- Website
- united.com
Flights from Wilkes-Barre/Scranton International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Newark Liberty International Airport to Louisville International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $75–450
Flights from Newark Liberty International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $75–460
Flights from Laguardia Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $190–1,000
- Website
- aa.com
Flights from Wilkes-Barre/Scranton International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Wilkes-Barre/Scranton International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,100
Flights from Newark Liberty International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $90–500
Flights from Laguardia Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $160–900
- Website
- delta.com
Flights from Newark Liberty International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–490
Flights from Laguardia Airport to Blue Grass Airport
- Ave. Duration
- 2h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–800
Flights from Laguardia Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Laguardia Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $160–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Indianapolis
- Ave. Duration
- 21h
- Frequency
- 3 times a week
- Estimated price
- $130–550
- Website
- https://www.amtrak.com/home.html
Train from Syracuse Regional Transportation Center to Toledo
- Ave. Duration
- 8h 8m
- Frequency
- Twice daily
- Estimated price
- $45–150
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $45–110
- Coach Seat short notice purchase
- $55–150
- Business - advance purchase
- $75–330
- Business Class
- $120–360
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Scranton to Buffalo
- Ave. Duration
- 5h 40m
- Frequency
- 5 times a day
- Estimated price
- $40–65
- Schedules at
- flixbus.com
Bus from Scranton to Newark Penn Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $29–65
- Schedules at
- flixbus.com
Bus from Scranton to Syracuse Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $29–45
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Buffalo, NY to Cincinnati, OH
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Cincinnati Bus Station to Lexington Bus Stop
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $16–50
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $29–75
- Website
- https://www.greyhound.com/
Bus from Scranton, PA to Port Authority Bus Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Toledo Bus Stop to Lexington Bus Stop
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Harrisburg Bus Station to Dayton Trotwood Bus Station
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
Bus from Dayton Trotwood Bus Station to Lexington Bus Stop
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 800-233-8604
- Website
- martzbus.com
Bus from Scranton, PA to Philadelphia 30th St Station
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $50–75
- Website
- https://martzbus.com
Bus from Scranton, PA to Port Authority Bus Terminal
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $60–85
- Website
- https://martzbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Scranton, PA to Harrisburg, PA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $20–65
- Website
- https://www.ourbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Scranton, PA to Harrisburg, PA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $24–75
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $24–70
- Flexible
- $45–75
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide

















