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How to get fromScranton to Des Moinesby plane, bus, train, bus (Flixbus), car or bus (Greyhound)

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There are 8 ways to get from Scranton to Des Moines by plane, bus, train, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM)plane plane AVP - DSM
    5h 54m
    $279–1,270

  2. Bus via Baltimore

    cheapest
    1. Take the bus from Scranton, PA to Harrisburg, PAbus bus
    2. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 9m
    $159–429

  3. Bus, train

    1. Take the bus from Scranton to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    24h 51m
    $160–423

  4. Bus

    1. Take the bus from Scranton, PA to Harrisburg, PAbus bus
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Des Moinesbus bus
    28h 50m
    $165–434

  5. Drive 1,016.7 mi

    1. Drive from Scranton to Des Moinescar car 1,016.7 mi
    16h 43m
    $186–268

  6. Bus to Lehigh Valley International Airport, fly

    1. Take the bus from Scranton Bus Station to Lehigh Valley International Airportbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Des Moines (DSM)plane plane ABE - DSM
    9h 26m
    $205–928

  7. Bus to Laguardia Airport, fly

    1. Take the bus from Scranton, PA to Port Authority Bus Terminalbus bus
    2. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    7h 54m
    $229–1,007

  8. Bus, train via Galesburg

    1. Take the bus from Scranton to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Burlingtonbus bus
    5. Take the bus from Burlington to Des Moinesbus bus
    26h 23m
    $200–473

Scranton to Des Moines by bus, train, and foot

Calendar14Weekly Services
Duration24h 51mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

What companies run services between Scranton, PA, USA and Des Moines, IA, USA?

United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Scranton, PA to Des Moines via Harrisburg, PA, Harrisburg Bus Station, and Chicago in around 28h 50m.

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