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How to get fromScranton to Des Moinesby plane, bus, train, bus (Flixbus), car or bus (Greyhound)

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There are 8 ways to get from Scranton to Des Moines by plane, bus, train, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM)planeAVP - DSM
    5h 23m
    $229–970

  2. Bus

    cheapest
    1. Take the bus from Scranton, PA to Harrisburg, PAbus
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus
    3. Take the bus from Chicago to Des Moinesbus
    28h 50m
    $165–394

  3. Bus, train

    1. Take the bus from Scranton to Syracuse Bus Stationbus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain
    3. Take the bus from Chicago to Des Moinesbus
    24h 51m
    $195–418

  4. Drive 1,016.7 mi

    1. Drive from Scranton to Des Moinescar1,016.7 mi
    16h 32m
    $186–268

  5. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Scranton to Newark Penn Stationbus
    2. Fly from Newark Liberty International Airport (EWR) to Des Moines (DSM)planeEWR - DSM
    6h 35m
    $199–854

  6. Bus to Lehigh Valley International Airport, fly

    1. Take the bus from Scranton Bus Station to Lehigh Valley International Airportbus
    2. Fly from Lehigh Valley International Airport (ABE) to Des Moines (DSM)planeABE - DSM
    8h 49m
    $195–878

  7. Bus, train via Galesburg

    1. Take the bus from Scranton to Syracuse Bus Stationbus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
    4. Take the bus from Galesburg to Burlingtonbus
    5. Take the bus from Burlington to Des Moinesbus
    26h 23m
    $229–468

  8. Bus via Baltimore

    1. Take the bus from Scranton, PA to Harrisburg, PAbus
    2. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus
    3. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus
    4. Take the bus from Chicago Bus Station to Des Moinesbus
    33h 50m
    $166–369

Scranton to Des Moines by bus, train, and foot

Calendar14Weekly Services
Duration24h 51mAverage Duration
Ticket$195Cheapest Price
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Questions & Answers

What companies run services between Scranton, PA, USA and Des Moines, IA, USA?

United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM) 5 times a day. Alternatively, you can take a bus from Scranton, PA to Des Moines via Harrisburg, PA, Harrisburg Bus Station, and Chicago in around 28h 50m.

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