There are 6 ways to get from Scranton to Des Moines by plane, bus, train, night bus or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended option
Fly
-
Fly from Scranton/Wilkes-Barre (AVP) to Des Moines (DSM)
Cheapest option
Bus, train, night bus
-
Take the bus from Scranton to Syracuse
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Take the train from Syracuse Regional Transportation Center to Chicago Union Station
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Take the night bus from Chicago, Il to Des Moines, Ia
4 alternative options
Bus, train
-
Take the bus from Scranton to Syracuse
-
Take the train from Syracuse Regional Transportation Center to Chicago Union Station
-
Take the bus from Chicago, Il to Des Moines, Ia
Bus, train via Galesburg
-
Take the bus from Scranton to Syracuse
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Take the train from Syracuse Regional Transportation Center to Chicago Union Station
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Take the train from Chicago Union Station to Galesburg Amtrak Station
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Take the bus from Galesburg, Il to Burlington, Ia
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Take the bus from Burlington, Ia to Des Moines, Ia
Bus
-
Take the bus from Scranton, PA to Harrisburg, PA
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Take the bus from Harrisburg to Kansas City
-
Take the bus from Kansas City, MO to Des Moines, IA
Drive
-
Drive from Scranton to Des Moines
Travel safe during COVID-19
Rules to follow in United States
2m
Recommended
Travel within United States
Observe COVID-19 safety rules
COVID-19 help in United States
If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636
Frequently Asked Questions
Yes, travel within United States is currently allowed.
Explore travel optionsDomestic travel is not restricted, but some conditions may apply
- Face masks are recommended
- There is a social distancing requirement of 2 metres
- Observe COVID-19 safety rules
The national COVID-19 helpline number in Des Moines is 800-232-4636.
Wearing a face mask on public transport in Des Moines is recommended.
The social distance requirement in Des Moines is 2 metres.
Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.
Last updated: 22 Mar 2023
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).
We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.
Questions & Answers
The cheapest way to get from Scranton to Des Moines is to bus and train and night bus which costs $140 - $260 and takes 24h 35m.
The quickest way to get from Scranton to Des Moines is to fly which costs $160 - $500 and takes 5h 8m.
No, there is no direct bus from Scranton to Des Moines. However, there are services departing from Scranton, PA and arriving at Des Moines, IA via Harrisburg and Kansas City, MO. The journey, including transfers, takes approximately 33h 25m.
The distance between Scranton and Des Moines is 932 miles. The road distance is 1024.9 miles.
The best way to get from Scranton to Des Moines without a car is to bus and train and night bus which takes 24h 35m and costs $140 - $260.
It takes approximately 5h 8m to get from Scranton to Des Moines, including transfers.
Scranton to Des Moines bus services, operated by OurBus, depart from Scranton, PA station.
The best way to get from Scranton to Des Moines is to fly which takes 5h 8m and costs $160 - $500. Alternatively, you can bus, which costs $160 - $260 and takes 33h 25m.
There is no direct flight from Scranton/Wilkes-Barre Airport to Des Moines Airport. The quickest flight takes 4h 46m and has one stopover.
Scranton to Des Moines bus services, operated by Jefferson Lines, arrive at Des Moines, IA station.

- Distance: 932.3 miles
- Duration: 5h 8m
What companies run services between Scranton, PA, USA and Des Moines, IA, USA?
United Airlines and American Airlines fly from Scranton to Des Moines hourly. Alternatively, you can take a bus from Scranton to Des Moines via Harrisburg, PA, Harrisburg, Kansas City, and Kansas City, MO in around 33h 25m.

- Website
- united.com
Flights from Scranton/Wilkes-Barre to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $100 - $450
Flights from Scranton/Wilkes-Barre to Des Moines via Newark, Chicago O'Hare
- Ave. Duration
- 8h 28m
- When
- Saturday and Sunday
- Estimated price
- $100 - $490
Flights from Scranton/Wilkes-Barre to Des Moines via Newark, Denver
- Ave. Duration
- 9h 36m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $130 - $750

- Website
- aa.com
Flights from Scranton/Wilkes-Barre to Des Moines via Charlotte
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $100 - $440
Flights from Scranton/Wilkes-Barre to Des Moines via Chicago O'Hare
- Ave. Duration
- 9h 41m
- When
- Monday, Thursday, Friday, Saturday and Sunday
- Estimated price
- $100 - $420
Flights from Scranton/Wilkes-Barre to Des Moines via Charlotte, Chicago O'Hare
- Ave. Duration
- 9h 7m
- When
- Monday, Thursday, Friday, Saturday and Sunday
- Estimated price
- $100 - $450

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.
Rome2rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $70 - $110
- Website
- https://www.amtrak.com/routes.html
- Coach Seat
- $70 - $110
- Premium
- $270 - $380
- Flexi Coach Seat
- $140 - $210
- Business Seat
- $150 - $220
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 3 times a day
- Estimated price
- $30 - $50
- Website
- https://www.amtrak.com/routes.html
- Coach Seat
- $30 - $50
- Premium
- $200 - $280
- Flexi Coach Seat
- $55 - $80
- Business Seat
- $50 - $80

- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Scranton to Syracuse
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $12 - $50
- Schedules at
- flixbus.com
- Adult Standard Purchase
- $18 - $50
- Adult Advance Purchase
- $12 - $17

- Phone
- 1(800) 992-4618
- Website
- burlingtontrailways.com
Night bus from Chicago, Il to Des Moines, Ia
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $60 - $90
- Book at
- burlingtontrailways.com
Bus from Galesburg, Il to Burlington, Ia
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $21 - $30
- Book at
- burlingtontrailways.com
Bus from Burlington, Ia to Des Moines, Ia
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $35 - $55
- Book at
- burlingtontrailways.com

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.
Rome2rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Scranton to Syracuse
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- $20 - $29
- Website
- https://www.greyhound.com/
- Economy
- $20 - $29
- Flexible
- $40 - $60
Bus from Harrisburg to Kansas City
- Ave. Duration
- 25h 20m
- Frequency
- Once daily
- Estimated price
- $100 - $150
- Website
- https://www.greyhound.com/
- Economy
- $100 - $150
- Flexible
- $150 - $230

- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Scranton, PA to Harrisburg, PA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $26 - $35
- Website
- https://www.ourbus.com/bookTicket

- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Scranton, Pa to Harrisburg, Pa
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $30 - $50
- Schedules at
- trailways.com

- Phone
- +1-858-800-8898
- info@jeffersonlines.com
- Website
- jeffersonlines.com
Bus from Kansas City, MO to Des Moines, IA
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- $40 - $60
- Book at
- jeffersonlines.com
Want to know more about travelling around United States
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Read the travel guideMore Questions & Answers
Des Moines is 1h behind Scranton. It is currently 2:00 PM in Scranton and 1:00 PM in Des Moines.
Yes, the driving distance between Scranton to Des Moines is 1025 miles. It takes approximately 16h 43m to drive from Scranton to Des Moines.
American Airlines and United Airlines offer flights from Scranton/Wilkes-Barre Airport to Des Moines Airport.
There are 111+ hotels available in Des Moines. Prices start at $100 USD per night.
The best way to get from Scranton to Scranton/Wilkes-Barre Airport is to taxi which takes 11 min and costs $40 - $55.