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How to get fromScranton to Des Moinesby plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Flixbus, Greyhound)

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There are 11 ways to get from Scranton to Des Moines by plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM)plane plane AVP - DSM
    5h 25m
    $259–1,020

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Scranton to Allentown Transportation Centerbus bus
    2. Take the bus from Allentown to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    27h 49m
    $161–302

  3. Bus, train

    1. Take the bus from Scranton Bus Station to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    24h 31m
    $265–553

  4. Drive 1,016.7 mi

    1. Drive from Scranton to Des Moinescar car 1,016.7 mi
    16h 43m
    $186–268

  5. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Scranton to Newark Penn Stationbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Des Moines (DSM)plane plane EWR - DSM
    6h 45m
    $209–870

  6. Bus to Lehigh Valley International Airport, fly

    1. Take the bus from Scranton Bus Station to Lehigh Valley International Airportbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Des Moines (DSM)plane plane ABE - DSM
    8h 48m
    $189–844

  7. Bus to Philadelphia International Airport, fly

    1. Take the bus from Scranton to Philadelphia 30th St Stationbus bus
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    7h 41m
    $323–1,297

  8. Bus to Greater Binghamton Airport, fly

    1. Take the bus from Scranton Bus Station to Binghamtonbus bus
    2. Fly from Greater Binghamton Airport (BGM) to Des Moines (DSM)plane plane BGM - DSM
    9h 53m
    $229–903

  9. Bus to Laguardia Airport, fly

    1. Take the bus from Scranton to Port Authority Bus Terminalbus bus
    2. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    7h 34m
    $253–1,068

  10. Bus, train via Galesburg

    1. Take the bus from Scranton to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    26h 18m
    $293–620

  11. Bus

    1. Take the bus from Scranton, Pa to Harrisburg, Pabus bus 771
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    28h 10m
    $170–339

Scranton to Des Moines by bus, train, and foot

Calendar7Weekly Services
Duration24h 31mAverage Duration
Ticket$265Cheapest Price
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Questions & Answers

Map of how to get from Scranton to Des Moines.ExpandLaunch map view
  • Distance: 941.8 mi
  • Duration: 5h 25m

What companies run services between Scranton, PA, USA and Des Moines, IA, USA?

United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Scranton to Des Moines via Allentown Transportation Center, Allentown, Indianapolis, and Indianapolis Union Station in around 27h 49m.

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