There are 6 ways to get from Scranton to Buffalo–Depew Station by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, train via Syracuse, NY  •  6 h 21 min

  1. Take the bus from Scranton, Pa to Binghamton, Ny 206 / ...
  2. Take the bus from Binghamton to Syracuse, NY
  3. Take the train from Syracuse Regional Transportation Center Amtrak to Buffalo Depew Station Amtrak

$62 - $172

Cheapest option

Bus  •  7 h 30 min

  1. Take the bus from Scranton, Pa to Syracuse, Ny 206 / ...
  2. Take the bus from Syracuse, Ny to Buffalo, Ny 4175 / ...

$43 - $97

4 alternative options

Bus, train  •  6 h 26 min

  1. Take the bus from Scranton, Pa to Rochester, Ny 300
  2. Take the train from Rochester Amtrak to Buffalo Depew Station Amtrak Lake Shore Limited / ...

$50 - $108

Drive  •  4 h 37 min

  1. Drive from Scranton to Buffalo–Depew Station 253.6 miles

$24 - $40

Fly from Scranton/Wilkes-Barre  •  5 h 21 min

  1. Fly from Scranton/Wilkes-Barre (AVP) to Buffalo (BUF) AVP - BUF

$206 - $904

Bus, bus to New York La Guardia, fly  •  7 h 54 min

  1. Take the bus from Scranton, Pa to Stroudsburg, Pa
  2. Take the bus from Stroudsburg/ Delaware Water Gap to New York, NY - P.A.B.T
  3. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$108 - $450

Questions & Answers

The cheapest way to get from Scranton to Buffalo–Depew Station is to drive which costs $24 - $40 and takes 4 h 37 min.

More details

The quickest way to get from Scranton to Buffalo–Depew Station is to drive which costs $24 - $40 and takes 4 h 37 min.

More details

The distance between Scranton and Buffalo–Depew Station is 189 miles. The road distance is 253.6 miles.

Get driving directions

It takes approximately 6 h 21 min to get from Scranton to Buffalo–Depew Station, including transfers.

More details

No, there is no direct bus from Scranton to Buffalo–Depew Station. However, there are services departing from Scranton, Pa and arriving at Walden Ave & 2929 Walden via Syracuse, Ny, Ellicott St & North Division St and Galleria Drway & Green Parking Entrance. The journey, including transfers, takes approximately 7 h 30 min.

More details

What companies run services between Scranton, PA, USA and Buffalo–Depew Station, NY, USA?

You can take a bus from Scranton to Buffalo–Depew Station via Syracuse, Ny, Buffalo, Ny, Ellicott St & North Division St, Galleria Drway & Green Parking Entrance, and Walden Ave & 2929 Walden in around 7 h 30 min. Alternatively, American Airlines, United Airlines and Delta fly from Scranton to Buffalo–Depew Station hourly.

Airlines
American Airlines
Website
aa.com
Flights from Scranton/Wilkes-Barre to Buffalo via Philadelphia
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$160 - $850
Flights from Scranton/Wilkes-Barre to Buffalo via Charlotte
Ave. Duration
4 h 57 min
When
Every day
Estimated price
$210 - $950
Flights from Scranton/Wilkes-Barre to Buffalo via Chicago O'Hare
Ave. Duration
6 h 33 min
When
Every day
Estimated price
$210 - $950
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3 h 27 min
When
Saturday
Estimated price
$130 - $800
Flights from New York La Guardia to Buffalo via Reagan Washington
Ave. Duration
3 h 46 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $800
Delta
Website
delta.com
Flights from Scranton/Wilkes-Barre to Buffalo via Detroit
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$160 - $850
Flights from Scranton/Wilkes-Barre to Buffalo via Atlanta
Ave. Duration
5 h 43 min
When
Saturday and Sunday
Estimated price
$220 - $1,000
Flights from New York La Guardia to Buffalo
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$100 - $700
Flights from New York La Guardia to Buffalo via Boston
Ave. Duration
3 h 50 min
When
Monday to Friday
Estimated price
$100 - $700
United Airlines
Website
united.com
Flights from Scranton/Wilkes-Barre to Buffalo via Washington Dulles
Ave. Duration
3 h 43 min
When
Thursday
Estimated price
$180 - $900
Flights from Scranton/Wilkes-Barre to Buffalo via Newark
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$170 - $850
Flights from Scranton/Wilkes-Barre to Buffalo via Chicago O'Hare
Ave. Duration
5 h 49 min
When
Every day
Estimated price
$220 - $1,000
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3 h 43 min
When
Monday to Saturday
Estimated price
$220 - $1,600
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Syracuse Regional Transportation Center Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
2 h 6 min
Frequency
Every 4 hours
Estimated price
$30 - $80
Website
amtrak.com
Coach Seat
$30 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $80
Room
$170 - $250
Train from Rochester Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
46 min
Frequency
Every 4 hours
Estimated price
$25 - $50
Website
amtrak.com
Coach Seat
$25 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Syracuse to Buffalo
Ave. Duration
2 h 18 min
Frequency
Every 3 hours
Estimated price
$30 - $95
Website
viarail.ca
Escape
$30 - $45
Economy
$45 - $65
Economy Plus
$70 - $95
Business
$65 - $90
Business Plus/Sleeper
$110 - $170
Train from Rochester to Buffalo
Ave. Duration
1 h 4 min
Frequency
Every 3 hours
Estimated price
$24 - $70
Website
viarail.ca
Escape
$24 - $35
Economy
$30 - $45
Economy Plus
$45 - $70
Business
$40 - $60
Business Plus/Sleeper
$75 - $110
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Scranton, Pa to Binghamton, Ny
Ave. Duration
1 h 15 min
Frequency
Every 30 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $18
Flexible
$21 - $28
Bus from Scranton, Pa to Rochester, Ny
Ave. Duration
4 h 55 min
Frequency
Hourly
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Bus from Scranton, Pa to Syracuse, Ny
Ave. Duration
2 h 40 min
Frequency
Hourly
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$30 - $45
Bus from Syracuse, Ny to Buffalo, Ny
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Scranton, Pa to Stroudsburg, Pa
Ave. Duration
1 h 5 min
Frequency
Every 30 minutes
Estimated price
$11 - $25
Website
greyhound.com
Economy
$11 - $16
Flexible
$19 - $25
Trailways New York
Website
trailwaysny.com
Bus from Binghamton to Syracuse, NY
Ave. Duration
1 h 15 min
Frequency
Every 4 hours
Estimated price
$19 - $65
Schedules at
trailwaysny.com
Book at
trailwaysny.com
Martz Trailways
Website
martztrailways.com
Bus from Scranton to Stroudsburg DWG
Ave. Duration
1 h 3 min
Frequency
Once daily
Estimated price
$20 - $28
Schedules at
martztrailways.com
Book at
martztrailways.com
Bus from Stroudsburg/ Delaware Water Gap to New York, NY - P.A.B.T
Ave. Duration
1 h 15 min
Frequency
Hourly
Estimated price
$24 - $50
Schedules at
martztrailways.com
Book at
martztrailways.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.