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There are 8 ways to get from Santorini to Sicily by plane, car ferry, bus, bus and ferry, train, car, ferry or night bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Catania  •  5 h 2 min

  1. Fly from Santorini (JTR) to Catania (CTA) JTR - CTA

$130 - $575

7 alternative options

Fly to Palermo  •  7 h 39 min

  1. Fly from Santorini (JTR) to Palermo (PMO) JTR - PMO

$150 - $578

Fly to Malta, car ferry  •  7 h 54 min

  1. Fly from Santorini (JTR) to Malta (MLA) JTR - MLA
  2. Take the car ferry from Valetta to Pozzallo

$234 - $705

Catamaran, bus, bus and ferry, train  •  41 h 19 min

  1. Take the Catamaran from Santorini to Piraeus
  2. Take the bus from Peiraias to Katerini
  3. Take the bus and ferry from Katerini to Ancona
  4. Take the train from Varano to Termoli 603 / ...
  5. Take the bus and ferry from Termoli to Palermo

$324 - $471

Catamaran, drive, car ferry, train  •  43 h 44 min

  1. Take the Catamaran from Santorini to Piraeus
  2. Drive from Piraeus to Patras
  3. Take the car ferry from Patras to Bari
  4. Take the train from Bari Centrale to Roma Termini Fa / ...
  5. Take the train from Roma Termini to Palermo Centrale Ic / ...

$325 - $605

Ferry, bus and ferry, bus, night bus  •  2 days 8 h

  1. Take the ferry from Santorini to Thessaloniki
  2. Take the bus and ferry from Thessaloniki to Ancona
  3. Take the bus from Ancona to Tarsia
  4. Take the night bus from Tarsia to Palermo, Palermo Autostazione

$281 - $437

Ferry, bus, car ferry, train  •  2 days 9 h

  1. Take the ferry from Santorini to Thessaloniki
  2. Take the bus from Thessaloniki to Durrës
  3. Take the car ferry from Durrës to Bari
  4. Take the bus from Bari-Porto to Salerno
  5. Take the train from Salerno to Palermo Centrale Ic / ...

$258 - $437

Catamaran, drive, car ferry, ferry  •  34 h 22 min

  1. Take the Catamaran from Santorini to Piraeus
  2. Drive from Piraeus to Patras
  3. Take the car ferry from Patras to Brindisi
  4. Drive from Brindisi to Reggio Calabria
  5. Take the ferry from Reggio Calabria to Messina Marittima
  6. Drive from Messina Marittima to Palermo

$237 - $407

Questions & Answers

The cheapest way to get from Santorini to Sicily is to fly which costs 110€ - 500€ and takes 5 h 2 min.

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The quickest way to get from Santorini to Sicily is to fly which costs 110€ - 500€ and takes 5 h 2 min.

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The distance between Santorini and Sicily is 1012 km.

The best way to get from Santorini to Sicily without a car is to Catamaran and bus and bus and ferry and train which takes 41 h 19 min and costs 280€ - 410€.

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It takes approximately 5 h 2 min to get from Santorini to Sicily, including transfers.

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There is no direct flight from Santorini Airport to Catania Airport. The quickest flight takes 6 h 30 min and has one stopover.

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Sicily is 1 h behind Santorini. It is currently 6:00 AM in Santorini and 5:00 AM in Sicily.

Aegean Airlines, Alitalia, Volotea and three other airlines offer flights from Santorini Airport to Catania Airport.

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There are 182+ hotels available in Sicily. Prices start at $40 USD per night.

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The best way to get from Santorini to Santorini Airport is to taxi which takes 3 min and costs 15€ - 19€.

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Map of how to get from Santorini to Sicily.
Launch map view
  • Distance: 632.3 miles
  • Duration: 5 h 2 min

What companies run services between Santorini, Greece and Sicily, Italy?

easyJet, Ryanair and four other airlines fly from Mesariá to Catania twice daily.

Airlines
Alitalia
Website
alitalia.com
Flights from Santorini to Catania via Rome
Ave. Duration
5 h 55 min
When
Saturday
Estimated price
$130 - $490
Flights from Santorini to Palermo via Athens, Rome
Ave. Duration
6 h 53 min
When
Every day
Estimated price
$120 - $700
Flights from Santorini to Malta via Rome
Ave. Duration
5 h 50 min
When
Saturday
Estimated price
$220 - $650
easyJet
Website
easyjet.com
Flights from Santorini to Catania via Milan Malpensa
Ave. Duration
6 h 37 min
When
Tuesday
Estimated price
$110 - $600
Flights from Santorini to Catania via Venice
Ave. Duration
8 h 25 min
When
Monday and Wednesday
Estimated price
$100 - $550
Flights from Santorini to Palermo via Milan Malpensa
Ave. Duration
9 h 20 min
When
Tuesday
Estimated price
$120 - $650
Ryanair
Website
ryanair.com
Flights from Santorini to Catania via Athens, Malta
Ave. Duration
7 h
When
Tuesday and Saturday
Estimated price
$40 - $230
Flights from Santorini to Catania via Rome
Ave. Duration
4 h 30 min
When
Saturday
Estimated price
$130 - $490
Flights from Santorini to Malta via Athens
Ave. Duration
4 h 12 min
When
Tuesday and Saturday
Estimated price
$35 - $200
Aegean Airlines
Website
aegeanair.com
Flights from Santorini to Catania via Athens
Ave. Duration
4 h 5 min
When
Friday and Sunday
Estimated price
$130 - $650
Flights from Santorini to Malta via Athens
Ave. Duration
5 h 21 min
When
Thursday, Friday and Sunday
Estimated price
$110 - $380
Volotea
Website
volotea.com
Flights from Santorini to Catania via Venice
Ave. Duration
8 h
When
Wednesday
Estimated price
$100 - $550
Air Malta
Website
airmalta.com
Flights from Santorini to Malta via Rome
Ave. Duration
5 h 50 min
When
Saturday
Estimated price
$220 - $650
Train operators
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Varano to Termoli
Ave. Duration
1 h 51 min
Frequency
Hourly
Estimated price
$17 - $40
Website
orario.trenitalia.com
1st Class
$30 - $36
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Bari Centrale to Roma Termini
Ave. Duration
4 h 1 min
Frequency
4 times a day
Estimated price
$55 - $80
Website
orario.trenitalia.com
Trenitalia Intercity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Palermo Centrale
Ave. Duration
11 h 39 min
Frequency
4 times a day
Estimated price
$80 - $100
Website
orario.trenitalia.com
Train from Salerno to Palermo Centrale
Ave. Duration
8 h 41 min
Frequency
4 times a day
Estimated price
$60 - $85
Website
orario.trenitalia.com
Bus operators
KTEL Pierias S.A.
Phone
23510 46720
Website
ktelpierias.gr
Bus from Peiraias to Katerini
Ave. Duration
6 h
Frequency
Once daily
Estimated price
$40
Schedules at
ktelpierias.gr
Portokalidis Tours
Website
portokalidistours.gr
Bus and ferry from Katerini to Ancona
Ave. Duration
12 h 9 min
Frequency
Once a week
Estimated price
$120 - $180
Schedules at
portokalidistours.gr
Bus and ferry from Thessaloniki to Ancona
Ave. Duration
12 h 48 min
Frequency
Once a week
Estimated price
$120 - $190
Schedules at
portokalidistours.gr
Autoservizi Salemi Srl
Phone
(+39) 0923 98.11.20
Website
autoservizisalemi.it
Bus and ferry from Termoli to Palermo
Ave. Duration
11 h 59 min
Frequency
Once daily
Estimated price
$65 - $95
Schedules at
autoservizisalemi.it
Busitalia Simet S.p.A.
Phone
+39 098 3520 315
Email
info@fsbusitaliafast.it
Website
fsbusitaliafast.it
Bus from Ancona to Tarsia
Ave. Duration
9 h 56 min
Frequency
3 times a week
Estimated price
$45 - $70
Schedules at
simetspa.it
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Night bus from Tarsia to Palermo, Palermo Autostazione
Ave. Duration
7 h 5 min
Frequency
Twice a week
Estimated price
$28 - $50
Website
flixbus.co.uk
Crazy Holidays
Phone
2310-241545
Website
crazyholidays.gr
Bus from Thessaloniki to Durrës
Ave. Duration
9 h 45 min
Frequency
3 times a day
Estimated price
$55 - $75
Schedules at
crazyholidays.gr
Marozzi VT
Phone
080 579 0211
Email
info@marozzivt.it
Website
marozzivt.it
Bus from Bari-Porto to Salerno
Ave. Duration
3 h 55 min
Frequency
Once daily
Estimated price
$23 - $28
Schedules at
marozzivt.it
Ferry operators
Virtu Ferries Ltd
Website
virtuferries.com
Car ferry from Valetta to Pozzallo
Ave. Duration
1 h 45 min
Frequency
Twice daily
Estimated price
$75 - $150
Schedules at
virtuferries.com
Low season
$75 - $90
High season
$142 - $147
Mid season
$125
Sea Jets
Phone
+30 210 4121001
Email
info@seajets.gr
Website
seajets.gr
Car ferry from Santorini to Piraeus
Ave. Duration
5 h
Frequency
Once daily
Estimated price
$60 - $90
Schedules at
seajets.gr
2nd Class
$60 - $90
1st Class
$75 - $100
Ferry from Santorini to Thessaloniki
Ave. Duration
21 h 15 min
Frequency
Twice a week
Estimated price
$75 - $110
Schedules at
seajets.gr
2nd Class
$75 - $110
1st Class
$90 - $130
Superfast ferries
Phone
+30 210 8919700
Email
superfast@superfast.com
Website
superfast.com
Car ferry from Patras to Bari
Ave. Duration
15 h 30 min
Frequency
Once daily
Estimated price
$90 - $270
Schedules at
superfast.com
Deck
$93 - $94
Aircraft-type seats
$105 - $106
2 bed inside cabin
$262 - $264
3 bed outside cabin
$210 - $260
Adria Ferries
Phone
071 50211621
Email
booking@adriaferries.com
Website
adriaferries.com
Car ferry from Durrës to Bari
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$70 - $130
Schedules at
adriaferries.com
Deck
$70 - $80
Car
$110 - $120
Inside cabin 2 beds
$105 - $115
Inner cabin 2 beds
$110 - $125
Grimaldi Lines
Metromare Dello Stretto
Website
metromaredellostretto.it
Ferry from Reggio Calabria to Messina Marittima
Ave. Duration
30 min
Frequency
Hourly
Estimated price
$4
Schedules at
metromaredellostretto.it

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