There are 3 ways to get from Santorini caldera to Mytilene by plane, car ferry, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santorini (JTR) to Mytilene International Airport Odysseas Elytis (MJT)JTR - MJT
3h 7m€102–289Ferry
cheapest- Take the ferry from Thira Santorini Port to SyrosHsw
- Take the ferry from Syros to MytileneBsf
21h 30m€78–165Car ferry, ferry
- Take the car ferry from Thira Santorini Port to Mykonos
- Take the ferry from Mykonos to MytileneBsf
14h 48m€168–257
Santorini (JTR) to Mytilene International Airport Odysseas Elytis (MJT) flights
Questions & Answers
The cheapest way to get from Santorini caldera to Mytilene is to ferry which costs €75 - €170 and takes 21h 30m.
The fastest way to get from Santorini caldera to Mytilene is to fly which takes 3h 7m and costs €100 - €290.
The distance between Santorini caldera and Mytilene is 319 km.
The best way to get from Santorini caldera to Mytilene without a car is to car ferry and ferry which takes 14h 48m and costs €160 - €260.
It takes approximately 3h 7m to get from Santorini caldera to Mytilene, including transfers.
There are 425+ hotels available in Mytilene.
What companies run services between Santorini caldera, Greece and Mytilene, Greece?
Aegean Airlines, Sky Express, and Ryanair fly from Santorini (JTR) to Mytilene International Airport Odysseas Elytis (MJT) 5 times a day. Alternatively, you can take a bus from Thira Airport to Mytilene via Fira, Santorini Port, Thira Santorini Port, and Syros in around 21h 30m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- en.aegeanair.com
Flights from Santorini to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 3h 14m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €90–140
- Website
- skyexpress.gr
Flights from Santorini to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 4h 32m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–240
- Phone
- +30 210 4121001
- info@seajets.gr
- Website
- seajets.com
Car ferry from Thira Santorini Port to Mykonos
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- €89–90
- Website
- https://www.seajets.com/
- Phone
- +30 212 222 4000
- booking@goldenstarferries.gr
- Website
- goldenstarferries.gr
Car ferry from Thira Santorini Port to Mykonos
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- €82–83
- Website
- https://goldenstarferries.gr/en
Ferry from Mykonos to Mytilene
- Ave. Duration
- 11h 30m
- Frequency
- Twice a week
- Estimated price
- €40–110
- Website
- https://www.bluestarferries.com/en-gb/
- Economy
- €40–60
- 2 Bed Inside Cabin
- €70–90
- 4 Bed Outside Cabin
- €65–80
- 2 Bed Lux Cabin
- €85–110
Ferry from Syros to Mytilene
- Ave. Duration
- 12h 35m
- Frequency
- Twice a week
- Estimated price
- €40–110
- Website
- https://www.bluestarferries.com/en-gb/
- Economy
- €40–60
- 2 Bed Inside Cabin
- €75–90
- 4 Bed Outside Cabin
- €70–85
- 2 Bed Lux Cabin
- €90–110
Ferry from Thira Santorini Port to Syros
- Ave. Duration
- 5h 55m
- Frequency
- Once a week
- Estimated price
- €35–50
- Website
- https://www.hellenicseaways.gr/en-gb
- Airplane Type Seats
- €35–50
Want to know more about travelling around Greece
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Getting around the Cyclades
Read the travel guide