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How to get fromSantorini Island to Sienaby plane, train, car ferry, bus, ferry, car or busferry

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There are 10 ways to get from Santorini Island to Siena by plane, train, car ferry, bus, ferry, car, or busferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Santorini (JTR) to Florence Peretola Airport (FLR)planeJTR - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain
    6h 55m
    €130–311

  2. Fly to Fiumicino International Airport, train

    cheapest
    1. Fly from Santorini (JTR) to Fiumicino International Airport (FCO)planeJTR - FCO
    2. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 30m
    €102–336

  3. Car ferry, train, bus

    1. Take the car ferry from Thira Santorini Port to Port of Piraeuscarferry
    2. Take the train from Piraeus to KorinthostrainRe
    3. Take the bus from Korinthos to Durrësbus
    4. Take the bus from Durrës to Roma, Autostazione Tiburtinabus
    5. Take the train from Roma Tiburtina to Florence Santa Maria Novellatrain
    6. Take the train from Firenze S.M.N. to SienatrainRe
    33h 14m

  4. Ferry, bus

    1. Take the ferry from Thira Santorini Port to SyrosferryHsw
    2. Take the ferry from Syros to ThessalonikiferryBsf
    3. Take the bus from Thessaloniki to Skopje Central Bus Stationbus
    4. Take the bus from Skopje, Transporten Centar to Sienabus
    2d 7h
    €232–345

  5. Car ferry, drive

    1. Take the car ferry from Thira Santorini Port to Port of Piraeuscarferry
    2. Drive from Port of Piraeus to Sienacar
    26h 49m
    €436–642

  6. Fly to Pisa International Airport, train

    1. Fly from Santorini (JTR) to Pisa International Airport (PSA)planeJTR - PSA
    2. Take the train from Pisa Centrale to Empolitrain
    3. Take the train from Empoli to Sienatrain
    8h 59m
    €133–280

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Santorini (JTR) to Bologna Guglielmo Marconi Airport (BLQ)planeJTR - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 39m
    €106–363

  8. Car ferry, bus and ferry, bus, train

    1. Take the car ferry from Thira Santorini Port to Heraklion Portcarferry
    2. Take the busferry from Heraklion to Ioanninabusferry
    3. Take the bus from Ioannina to Durrësbus
    4. Take the bus from Durrës to Roma, Autostazione Tiburtinabus
    5. Take the train from Roma Tiburtina to Florence Santa Maria Novellatrain
    6. Take the train from Firenze S.M.N. to SienatrainRe
    38h 37m

  9. Car ferry, bus

    1. Take the car ferry from Thira Santorini Port to Port of Piraeuscarferry
    2. Take the bus from Athens Larissis Station to Vlorëbus
    3. Take the bus from Vlorë to Firenzebus
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131
    42h 7m

  10. Car ferry, bus and ferry, bus

    1. Take the car ferry from Thira Santorini Port to Heraklion Portcarferry
    2. Take the busferry from Heraklion Port to Tiranabusferry
    3. Take the bus from Tirana to Kavajëbus
    4. Take the bus from Kavajë to Perugiabus
    5. Take the bus from Perugia to Sienabus
    42h 24m

Santorini (JTR) to Florence Peretola Airport (FLR) flights

Calendar7Weekly Planes
Duration5h 51mAverage Duration
Ticket€114Cheapest Price
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Questions & Answers

What companies run services between Santorini Island, Greece and Siena, Italy?

There is no direct connection from Santorini Island to Siena. However, you can fly to Florence Peretola Airport (FLR), walk to Florence Airport (FLR), take the vehicle to Alamanni - Stazione Smn, walk to Firenze S.M.N., then take the train to Siena. Alternatively, you can take a car ferry from Thira Santorini Port to Siena via Port Of Piraeus, Piraeus, Korinthos, Korinthos, Durrës, Roma, Autostazione Tiburtina, Roma Tiburtina, and Firenze S.M.N. in around 33h 14m.

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