There are 4 ways to get from Santiago to Quito by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  10 h 18 min

  1. Fly from Santiago (SCL) to Quito (UIO) SCL - UIO

$215 - $1,037

3 alternative options

Bus Expresos Los Llanos  •  2 days 13 h

  1. Take the bus from Santiago to Tacna Via Bogota
  2. Take the bus from Cúcuta to Quito Via Santiago

$501 - $538

Bus Cruz del Sur  •  3 days 22 h

  1. Take the bus from Santiago to Lima Javier Prado Via Lima
  2. Take the bus from Lima Javier Prado to Quito Via Quito

$232 - $402

Drive  •  2 days 19 h

  1. Drive from Santiago to Quito 3233 miles

$500 - $800

Questions & Answers

The cheapest way to get from Santiago to Quito is to fly which costs $210 - $1,100 and takes 10 h 18 min.

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The quickest way to get from Santiago to Quito is to fly which costs $210 - $1,100 and takes 10 h 18 min.

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No, there is no direct bus from Santiago to Quito. However, there are services departing from PA448 - Avenida Matta Esq. / San Diego and arriving at San Diego via Santiago, Lima Javier Prado and Terminal Quitumbe. The journey, including transfers, takes approximately 3 days 22 h.

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The distance between Santiago and Quito is 3785 km. The road distance is 5172.8 km.

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The best way to get from Santiago to Quito without a car is to bus which takes 2 days 13 h and costs $500 - $540.

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It takes approximately 10 h 18 min to get from Santiago to Quito, including transfers.

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Santiago to Quito bus services, operated by Cruz del Sur, depart from Santiago station.

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The best way to get from Santiago to Quito is to fly which takes 10 h 18 min and costs $210 - $1,100. Alternatively, you can bus, which costs $500 - $540 and takes 2 days 13 h.

Mode details

There is no direct flight from Santiago Airport to Quito Airport. The quickest flight takes 7 h 49 min and has one stopover.

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Santiago to Quito bus services, operated by Cruz del Sur, arrive at Quito station.

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Map of how to get from Santiago to Quito.
Launch map view
  • Distance: 2365.8 miles
  • Duration: 10 h 18 min

What companies run services between Santiago, Chile and Quito, Ecuador?

LATAM Chile, Avianca - Aerovías del Continente Americano S.A. and three other airlines fly from Santiago to Quito hourly. Alternatively, you can take a bus from Santiago to Quito via Tacna, Cúcuta, Quito, and Terminal Quitumbe in around 2 days 13 h.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to Quito via Lima
Ave. Duration
8 h 34 min
When
Every day
Estimated price
$360 - $1,800
Flights from Santiago to Quito via Buenos Aires Ministro Pistarini, Lima
Ave. Duration
12 h 2 min
When
Every day
Estimated price
$360 - $1,800
Flights from Santiago to Quito via Santa Cruz, Lima
Ave. Duration
12 h 39 min
When
Monday, Wednesday and Friday
Estimated price
$360 - $1,800
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Santiago to Quito via Lima
Ave. Duration
8 h 7 min
When
Every day
Estimated price
$350 - $1,000
Flights from Santiago to Quito via Bogota
Ave. Duration
10 h 16 min
When
Every day
Estimated price
$350 - $1,000
Flights from Santiago to Quito via Lima, Guayaquil
Ave. Duration
9 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,000
Flights from Santiago to Quito via Lima, Bogota
Ave. Duration
11 h 5 min
When
Every day
Estimated price
$350 - $1,000
Copa Airlines
Website
copaair.com
Flights from Santiago to Quito via Panama City
Ave. Duration
11 h 34 min
When
Every day
Estimated price
$380 - $1,400
Bus operators
Cruz del Sur
Phone
+51 1 311-5050
Website
cruzdelsur.com.pe
Bus from Santiago to Lima Javier Prado
Ave. Duration
2 days 8 h
Frequency
5 times a week
Estimated price
$130 - $220
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Bus from Lima Javier Prado to Quito
Ave. Duration
35 h 35 min
Frequency
Once a week
Estimated price
$100 - $180
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe

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More Questions & Answers

Quito is 1 h behind Santiago. It is currently 10:51 PM in Santiago and 8:51 PM in Quito.

Yes, the driving distance between Santiago to Quito is 5173 km. It takes approximately 2 days 19 h to drive from Santiago to Quito.

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Copa Airlines, Avianca - Aerovías del Continente Americano S.A. and LATAM Chile offer flights from Santiago Airport to Quito Airport.

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There are 793+ hotels available in Quito. Prices start at $17 USD per night.

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The best way to get from Santiago to Santiago Airport is to Colectivo which takes 30 min and costs $10 - $45.

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