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There are 5 ways to get from Santiago to Mendoza by bus, car, plane or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6h 38m

  1. Take the bus from Santiago to Ovalle Santiago

$30 - $47

4 alternative options

Bus via Los Vilos  •  7h 3m

  1. Take the bus from Santiago to Los Vilos Salamanca / ...
  2. Take the bus from Los Vilos to Ovalle Santiago

Bus Expreso Norte  •  8h 9m

  1. Take the bus from Santiago to Ovalle Santiago

$31 - $53

Drive  •  5h 11m

  1. Drive from Santiago to Mendoza 282.2 miles

$45 - $70

Fly, bus, taxi  •  5h 45m

  1. Fly from Santiago (SCL) to La Serena (LSC) SCL - LSC
  2. Take the bus from La Serena to Recoleta
  3. Take a taxi from Recoleta to Mendoza

$68 - $255

Questions & Answers

The cheapest way to get from Santiago to Mendoza is to bus which costs $30 - $50 and takes 6h 38m.

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The quickest way to get from Santiago to Mendoza is to drive which costs $45 - $70 and takes 5h 11m.

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The distance between Santiago and Mendoza is 330 km. The road distance is 451.5 km.

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The best way to get from Santiago to Mendoza without a car is to bus which takes 6h 38m and costs $30 - $50.

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It takes approximately 6h 38m to get from Santiago to Mendoza, including transfers.

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The quickest flight from Santiago Airport to La Serena Airport is the direct flight which takes 1h 4m.

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Yes, the driving distance between Santiago to Mendoza is 451 km. It takes approximately 5h 11m to drive from Santiago to Mendoza.

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JetSMART, Sky Airline and LATAM Chile offer flights from Santiago Airport to La Serena Airport.

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There are four+ hotels available in Mendoza. Prices start at $100 USD per night.

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The best way to get from Santiago to Santiago Airport is to Colectivo which takes 30m and costs $10 - $45.

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Map of how to get from Santiago to Mendoza.
Launch map view
  • Distance: 206.1 miles
  • Duration: 6h 38m

What companies run services between Santiago, Chile and Mendoza, Chile?

Pluss Chile operates a bus from Santiago to Mendoza every 2 hours. Tickets cost $23 and the journey takes 5h 15m. Four other operators also service this route.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to La Serena
Ave. Duration
1h 4m
When
Every day
Estimated price
$120 - $600
Sky Airline
Website
skyairline.com
Flights from Santiago to La Serena
Ave. Duration
1h 5m
When
Every day
Estimated price
$55 - $350
JetSMART
Website
jetsmart.com
Flights from Santiago to La Serena
Ave. Duration
1h 5m
When
Every day
Estimated price
$35 - $300
Bus operators
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Santiago to Ovalle
Ave. Duration
5h 15m
Frequency
Every 2 hours
Estimated price
$23
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Bus from Los Vilos to Ovalle
Ave. Duration
2h 15m
Frequency
Every 2 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Santiago - Terminal San Borja to Ovalle
Ave. Duration
5h 15m
Frequency
4 times a day
Estimated price
$9 - $20
Book at
pasajebus.com
2nd Class
$9 - $20
Premium
$23 - $35
1st Class
$22 - $35
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Santiago to Ovalle
Ave. Duration
5h 10m
Frequency
Twice daily
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Pullman Bus
Phone
+56 600 600 0018
Website
pullmanbus.com
Bus from Santiago to Ovalle
Ave. Duration
5h 45m
Frequency
Twice daily
Estimated price
$14 - $18
Schedules at
pullmanbus.com
Bus from Santiago to Los Vilos
Ave. Duration
2h 40m
Frequency
Every 3 hours
Estimated price
$8 - $15
Schedules at
pullmanbus.com
Los Corsarios
Phone
+56 02-7205231
Website
loscorsarios.cl
Bus from Santiago to Ovalle
Ave. Duration
6h
Frequency
Once daily
Estimated price
$16
Schedules at
viajaenbus.cl
Buses Paravias
Website
paravias.com
Bus from Santiago to Los Vilos
Ave. Duration
2h 44m
Frequency
4 times a day
Schedules at
paravias.com
Cormarbus
Phone
532 623851
Email
cormarbus1@gmail.com
Website
cormarbus.cl
Bus from La Serena to Recoleta
Ave. Duration
1h 8m
Frequency
Every 15 minutes
Estimated price
$4
Schedules at
cormarbus.cl
Other operators
Taxi from Recoleta to Mendoza
Ave. Duration
1h 4m
Estimated price
$21 - $25
Transporte Taxi Privado
Phone
+56 95 459 0910
Trans Antonio
Phone
+56 95 061 0019
Radio Taxi Montana
Phone
+56 53 262 6222

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