There are 5 ways to get from Santiago to Mendoza by bus, car, plane or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus Expreso Norte  •  6 h 53 min

  1. Take the bus from Santiago to Ovalle Santiago

$31 - $59

4 alternative options

Bus via Los Vilos  •  7 h 11 min

  1. Take the bus from Santiago to Los Vilos Salamanca / ...
  2. Take the bus from Los Vilos to Ovalle

Bus Turbus  •  7 h 49 min

  1. Take the bus from Santiago to Ovalle Santiago

$37 - $69

Drive  •  5 h 11 min

  1. Drive from Santiago to Mendoza 282.2 miles

$45 - $70

Fly, bus, taxi  •  5 h 43 min

  1. Fly from Santiago (SCL) to La Serena (LSC) SCL - LSC
  2. Take the bus from La Serena to Recoleta
  3. Take a taxi from Recoleta to Mendoza

$69 - $258

Questions & Answers

The cheapest way to get from Santiago to Mendoza is to bus which costs $30 - $60 and takes 6 h 53 min.

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The quickest way to get from Santiago to Mendoza is to drive which costs $45 - $70 and takes 5 h 11 min.

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The distance between Santiago and Mendoza is 330 km. The road distance is 451.5 km.

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The best way to get from Santiago to Mendoza without a car is to bus which takes 6 h 53 min and costs $30 - $60.

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It takes approximately 6 h 53 min to get from Santiago to Mendoza, including transfers.

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The quickest flight from Santiago Airport to La Serena Airport is the direct flight which takes 1 h 2 min.

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Yes, the driving distance between Santiago to Mendoza is 451 km. It takes approximately 5 h 11 min to drive from Santiago to Mendoza.

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Sky Airline and LATAM Chile offer flights from Santiago Airport to La Serena Airport.

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There are four+ hotels available in Mendoza. Prices start at $100 USD per night.

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The best way to get from Santiago to Santiago Airport is to Colectivo which takes 30 min and costs $10 - $45.

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Map of how to get from Santiago to Mendoza.
Launch map view
  • Distance: 206.1 miles
  • Duration: 6 h 53 min

What companies run services between Santiago, Chile and Mendoza, Chile?

Expreso Norte operates a bus from Santiago to Mendoza 4 times a day. Tickets cost $19 - $27 and the journey takes 5 h 30 min. Turbus also services this route 3 times a day.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to La Serena
Ave. Duration
1 h 2 min
When
Every day
Estimated price
$120 - $600
Sky Airline
Website
skyairline.com
Flights from Santiago to La Serena
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$55 - $350
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Santiago - Terminal Alameda to Ovalle
Ave. Duration
5 h 15 min
Frequency
3 times a day
Estimated price
$9 - $35
Schedules at
turbus.cl
2nd Class
$9 - $20
Premium
$24 - $35
1st Class
$22 - $35
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Santiago to Los Vilos
Ave. Duration
2 h 40 min
Frequency
Every 3 hours
Estimated price
$8 - $15
Schedules at
pullman.cl
Buses Paravias
Website
paravias.com
Bus from Santiago to Los Vilos
Ave. Duration
2 h 44 min
Frequency
4 times a day
Schedules at
paravias.com
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Santiago to Los Vilos
Ave. Duration
2 h 47 min
Frequency
4 times a day
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Bus from Los Vilos to Ovalle
Ave. Duration
2 h 23 min
Frequency
Every 3 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Cormarbus
Phone
532 623851
Email
cormarbus1@gmail.com
Website
cormarbus.cl
Bus from La Serena to Recoleta
Ave. Duration
1 h 8 min
Frequency
Every 15 minutes
Estimated price
$5
Schedules at
cormarbus.cl
Other operators
Taxi from Recoleta to Mendoza
Ave. Duration
1 h 4 min
Estimated price
$21 - $26
Trans Antonio
Phone
+56 95 061 0019
Radio Taxi Montana
Phone
+56 53 262 6222
Transporte Taxi Privado
Phone
+56 95 459 0910

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