There are 4 ways to get from Santiago to Mendoza by bus, car, plane or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus Pluss Chile  •  6 h 41 min

  1. Take the bus from Santiago - San Borja to Ovalle Santiago

$38 - $70

Cheapest option

Bus Turbus  •  7 h 54 min

  1. Take the bus from Santiago - Terminal Alameda to Ovalle Santiago

$34 - $69

2 alternative options

Drive  •  5 h 11 min

  1. Drive from Santiago to Mendoza 282.2 miles

$45 - $70

Fly, bus, taxi  •  5 h 44 min

  1. Fly from Santiago (SCL) to La Serena (LSC) SCL - LSC
  2. Take the bus from La Serena to Recoleta
  3. Take a taxi from Recoleta to Mendoza

$67 - $258

What companies run services between Santiago, Chile and Mendoza, Chile?

Pluss Chile operates a bus from Santiago to Mendoza every 3 hours, and the journey takes 5 h 33 min. Two other operators also service this route.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to La Serena
Ave. Duration
1 h 3 min
When
Every day
Estimated price
$120 - $600
Sky Airline
Website
skyairline.com
Flights from Santiago to La Serena
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$55 - $350
JetSMART
Website
jetsmart.com
Flights from Santiago to La Serena
Ave. Duration
1 h 5 min
When
Tuesday, Wednesday, Friday, Saturday and Sunday
Estimated price
$35 - $300
Bus operators
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Santiago - San Borja to Ovalle
Ave. Duration
5 h 33 min
Frequency
Every 3 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Santiago to Ovalle
Ave. Duration
5 h 18 min
Frequency
Every 4 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Turbus
Website
turbus.cl
Bus from Santiago - Terminal San Borja to Ovalle
Ave. Duration
5 h 15 min
Frequency
Once daily
Estimated price
$10 - $40
Schedules at
turbus.cl
2nd Class
$10 - $22
Premium
$25 - $40
1st Class
$24 - $35
Bus from Santiago - Terminal Alameda to Ovalle
Ave. Duration
5 h 15 min
Frequency
3 times a day
Estimated price
$10 - $40
Schedules at
turbus.cl
2nd Class
$10 - $22
Premium
$25 - $40
1st Class
$24 - $35
Cormarbus
Phone
532 623851
Email
cormarbus1@gmail.com
Website
cormarbus.cl
Bus from La Serena to Recoleta
Ave. Duration
1 h 8 min
Frequency
Every 15 minutes
Estimated price
$5
Schedules at
cormarbus.cl
Other operators
Taxi from Recoleta to Mendoza
Ave. Duration
1 h 4 min
Estimated price
$23 - $28
Radio Taxi Montana
Phone
+56 53 262 6222
Transporte Taxi Privado
Phone
+56 95 459 0910
Trans Antonio
Phone
+56 95 061 0019

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including French strikes 2018: What are my alternative transport options?, How to get from Florence to Rome and Train travel in France: A guide to SNCF - to help you get the most out of your next trip.

Questions & Answers

The distance between Santiago and Mendoza is 330 km. The road distance is 451 km.

The cheapest way to get from Santiago to Mendoza is to bus which costs $30 - $70 and takes 7 h 54 min.

The quickest way to get from Santiago to Mendoza is to drive which takes 5 h 11 min and costs $45 - $70.

It takes approximately 6 h 41 min to get from Santiago to Mendoza, including transfers.