There are 5 ways to get from Santiago to Cusco by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  6 h

  1. Fly from Santiago (SCL) to Cuzco (CUZ) SCL - CUZ

$193 - $846

Cheapest option

Bus via Arequipa  •  40 h 4 min

  1. Take the bus from Santiago to Tacna
  2. Take the bus from Tacna to Arequipa
  3. Take the bus from Arequipa to Cusco

$106 - $198

3 alternative options

Bus  •  40 h

  1. Take the bus from Santiago to Tacna
  2. Take the bus from Tacna to Puno
  3. Take the bus from Puno to Cusco

Bus Turbus  •  2 days 2 h

  1. Take the bus from Santiago - Terminal Alameda to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the bus from Arequipa to Cusco

$128 - $280

Drive  •  36 h 32 min

  1. Drive from Santiago to Cusco 1806.9 miles

$290 - $440

Questions & Answers

The cheapest way to get from Santiago to Cusco is to bus which costs $100 - $200 and takes 40 h 4 min.

More details

The quickest way to get from Santiago to Cusco is to fly which costs $190 - $850 and takes 6 h.

More details

The distance between Santiago and Cusco is 2221 km. The road distance is 2891.1 km.

Get driving directions

It takes approximately 6 h to get from Santiago to Cusco, including transfers.

More details

No, there is no direct bus from Santiago to Cusco. However, there are services departing from Santiago and arriving at Cusco via Tacna and Puno. The journey, including transfers, takes approximately 40 h.

More details

What companies run services between Santiago, Chile and Cusco, Peru?

LATAM Chile and Avianca - Aerovías del Continente Americano S.A. fly from Santiago to Cusco every 2 hours. Alternatively, you can take a bus from Santiago to Cusco via Tacna and Puno in around 40 h.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to Cuzco
Ave. Duration
3 h 25 min
When
Tuesday, Wednesday and Saturday
Estimated price
$360 - $950
Flights from Santiago to Cuzco via Lima
Ave. Duration
6 h 41 min
When
Every day
Estimated price
$360 - $950
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Santiago to Cuzco via Lima
Ave. Duration
7 h 25 min
When
Every day
Estimated price
$220 - $1,300
Bus operators
Inka Express
Phone
0051 084 247887
Email
reservascusco@inkaexpress.com
Website
inkaexpress.com.pe
Bus from Puno to Cusco
Ave. Duration
6 h
Frequency
Once daily
Estimated price
$50
Schedules at
inkaexpress.com.pe
Oltursa
Website
oltursa.pe
Bus from Tacna to Arequipa
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$10 - $26
Schedules at
oltursa.pe
Bus from Arequipa to Cusco
Ave. Duration
10 h 15 min
Frequency
Twice daily
Estimated price
$15 - $35
Schedules at
oltursa.pe
Movil Tours
Phone
716-8000
Email
info@moviltours.com.pe
Website
moviltours.com.pe
Bus from Arequipa to Cusco
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$18 - $60
Schedules at
moviltours.com.pe
Economy
$21 - $35
Regular
$28 - $40
Suite
$40 - $60
Transzela
Turbus
Website
turbus.cl
Bus from Santiago - Terminal Alameda to Arica
Ave. Duration
28 h 55 min
Frequency
Twice daily
Estimated price
$45 - $130
Schedules at
turbus.cl
2nd Class
$45 - $90
Premium
$90 - $130
1st Class
$120 - $180
Pullman San Andrés
Phone
+56 98 400 8951
Email
pullmansanandres@gmail.com
Website
facebook.com
Bus from Santiago to Arica
Ave. Duration
29 h 30 min
Frequency
Once daily
Schedules at
facebook.com
bus
Bus from Arica to Tacna
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$3
Peru Hop
Phone
+51 1 2422140
Email
info@peruhop.com
Bus from Arequipa to Cusco
Ave. Duration
11 h 45 min
Frequency
5 times a week
Estimated price
$70 - $120
Schedules at
peruhop.com
Book at
peruhop.com

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