There are 4 ways to get from Santiago to Cusco by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  8 h 37 min

  1. Fly from Santiago (SCL) to Cuzco (CUZ) SCL - CUZ

$194 - $851

Cheapest option

Bus  •  2 days 0 h

  1. Take the bus from Santiago to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Cusco

$92 - $132

2 alternative options

Bus, train  •  2 days 1 h

  1. Take the bus from Santiago to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Puno
  4. Take the train from Puno to Cusco - Wanchaq

Drive  •  36 h 32 min

  1. Drive from Santiago to Cusco 1806.9 miles

$290 - $440

What companies run services between Santiago, Chile and Cusco, Peru?

LATAM Chile, Avianca - Aerovías del Continente Americano S.A. and JetSMART fly from Santiago to Cusco hourly. Alternatively, you can take a bus from Santiago to Cusco via Arica and Tacna in around 2 days 0 h.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to Cuzco via Lima
Ave. Duration
7 h 11 min
When
Every day
Estimated price
$360 - $950
Flights from Santiago to Cuzco via Lima, Trujillo
Ave. Duration
10 h 15 min
When
Tuesday
Estimated price
$360 - $950
Flights from Santiago to Cuzco via Buenos Aires Ministro Pistarini, Lima
Ave. Duration
10 h 50 min
When
Every day
Estimated price
$360 - $950
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Santiago to Cuzco via Lima
Ave. Duration
7 h 34 min
When
Every day
Estimated price
$220 - $1,300
Flights from Santiago to Cuzco via Bogota
Ave. Duration
11 h 39 min
When
Every day
Estimated price
$220 - $1,300
Train operators
PeruRail
Phone
51-84-581414
Email
reservas@perurail.com
Website
perurail.com
Train from Puno to Cusco - Wanchaq
Ave. Duration
10 h 20 min
Frequency
3 times a week
Estimated price
$210 - $3,100
Schedules at
perurail.com
Book at
pax1.perurail.com
VIP
$210 - $3,100
Regular
$330 - $460
Bus operators
Fichtur VIP
Phone
+56 (02) 7205232
Website
fichtur.cl
Bus from Santiago to Arica
Ave. Duration
27 h 20 min
Frequency
3 times a day
Estimated price
$57
Schedules at
viajaenbus.cl
Terminal Internacional ASEVERTRANS Ltda
Phone
(58) 241 390
Website
terminaldebuses.com
Bus from Arica to Tacna
Ave. Duration
2 h
Frequency
Every 30 minutes
Estimated price
$7
Schedules at
terminaldebuses.com
Expreso Turismo San Martin Nobleza
Phone
+51 951977185
Website
facebook.com
Bus from Tacna to Puno
Ave. Duration
8 h
Frequency
4 times a day
Schedules at
facebook.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Need to know: Jadrolinija, Want to know more about US trains? and Need to know: Eurostar - to help you get the most out of your next trip.

Questions & Answers

How far is it from Santiago to Cusco?

The distance between Santiago and Cusco is 2221 km. The road distance is 2891 km.

What is the cheapest way to get from Santiago to Cusco?

The cheapest way to get from Santiago to Cusco is to bus which costs $90 - $140 and takes 2 days 0 h.

What is the fastest way to get from Santiago to Cusco?

The quickest way to get from Santiago to Cusco is to fly which takes 8 h 37 min and costs $190 - $850.

Is there a direct bus between Santiago and Cusco?

No, there is no direct bus from Santiago to Cusco. However, there are services departing from Santiago and arriving at Cusco via Arica and Tacna. The journey, including transfers, takes approximately 2 days 0 h.

How long does it take to get from Santiago to Cusco?

It takes approximately 8 h 37 min to get from Santiago to Cusco, including transfers.