There are 8 ways to get from Santiago to Cuenca by plane, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cuenca
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE)plane SCL - CUE
11h 24m$272–703Bus via Piura
cheapest- Take the bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Gran Terminal Terrestre Plaza Norte to Piurabus
- Take the bus from Piura to Cuencabus
3d 13h$144–278Bus via Chiclayo
- Take the bus from Terminal San Borja to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Lima to Chiclayobus
- Take the bus from Chiclayo to Cuencabus
3d 1h$288–368Drive 4,669.2 km
- Drive from Santiago to Cuencacar 4,669.2 km
2d 13h$576–832Fly to José Joaquín De Olmedo International Airport, taxi
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to José Joaquín De Olmedo International Airport (GYE)plane SCL - GYE
- Take the taxi from Guayaquil-Airport-GYE to Cuencataxi
10h 42m$342–693Fly to Tumbes, bus
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tumbes (TBP)plane SCL - TBP
- Take the bus from Huaquillas to Cuencabus
14h 29m$243–407Bus
- Take the bus from Terminal San Borja to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Lima Paseo de la República to Tumbesbus
- Take the bus from Huaquillas to Cuencabus
3d 3h$277–387Bus #2
- Take the bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Gran Terminal Terrestre Plaza Norte to Terminal Terrestre de Guayaquilbus
- Take the bus from Terminal Terrestre de Guayaquil to Cuencabus
3d 15h$207–333
Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE) flights
Questions & Answers
The cheapest way to get from Santiago to Cuenca is to bus via Piura which costs $140 - $280 and takes 3 days 13h.
The fastest way to get from Santiago to Cuenca is to fly and taxi which takes 10h 42m and costs $340 - $700.
No, there is no direct bus from Santiago to Cuenca. However, there are services departing from Terminal San Borja and arriving at Cuenca via Gran Terminal Terrestre Plaza Norte, Lima and Chiclayo. The journey, including transfers, takes approximately 3 days 1h.
The distance between Santiago and Cuenca is 3511 km. The road distance is 4669.2 km.
The best way to get from Santiago to Cuenca without a car is to bus via Chiclayo which takes 3 days 1h and costs $280 - $370.
It takes approximately 11h 24m to get from Santiago to Cuenca, including transfers.
Santiago to Cuenca bus services, operated by Lineas de Los Andes, depart from Terminal San Borja station.
The best way to get from Santiago to Cuenca is to fly which takes 11h 24m and costs $270 - $750. Alternatively, you can bus via Chiclayo, which costs $280 - $370 and takes 3 days 1h.
Santiago to Cuenca bus services, operated by Lineas de Los Andes, arrive at Gran Terminal Terrestre Plaza Norte station.
Cuenca is 2h behind Santiago. It is currently 9:20 AM in Santiago and 7:20 AM in Cuenca.
What companies run services between Santiago, Chile and Cuenca, Ecuador?
LATAM Chile flies from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE) 3 times a day. Alternatively, you can take a bus from Terminal San Borja to Cuenca via Gran Terminal Terrestre Plaza Norte, Lima, Lima, and Chiclayo in around 3d 1h.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via José Joaquín De Olmedo International Airport
- Ave. Duration
- 9h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $330–750
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Lima, Quito
- Ave. Duration
- 10h 11m
- When
- Monday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $330–750
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via José Joaquín De Olmedo International Airport, Quito
- Ave. Duration
- 12h 44m
- When
- Wednesday
- Estimated price
- $330–750
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Lima, José Joaquín De Olmedo International Airport
- Ave. Duration
- 13h 28m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $330–750
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Bogota, Quito
- Ave. Duration
- 15h 23m
- When
- Tuesday
- Estimated price
- $330–750
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $230–550
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport via Lima
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $230–550
Flights from Comodoro Arturo Merino Benítez International Airport to Tumbes via Lima
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $250–600
- Website
- avianca.com
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 9h 16m
- When
- Every day
- Estimated price
- $230–700
- Website
- skyairline.com
Flights from Comodoro Arturo Merino Benítez International Airport to Tumbes via Lima
- Ave. Duration
- 10h 10m
- When
- Every day
- Estimated price
- $160–600
- Phone
- +51 9 6788 4526
- servicioalcliente@lineasdelosandes.com
- Website
- facebook.com
Bus from Terminal San Borja to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 2d 3h
- Frequency
- Once daily
- Estimated price
- $210–260
- Website
- https://www.facebook.com/lineasdelosandesve/
Bus from Gran Terminal Terrestre Plaza Norte to Terminal Terrestre de Guayaquil
- Ave. Duration
- 27h
- Frequency
- Once daily
- Estimated price
- $100–130
- Website
- https://www.facebook.com/lineasdelosandesve/
Bus from Lima to Chiclayo
- Ave. Duration
- 10h 30m
- Frequency
- Hourly
- Estimated price
- $36
- Schedules at
- terramovilperu.com.pe
- Book at
- redbus.pe
- Phone
- +593-07 2823163
- gerencia@transportesazuay.com
- Website
- transportesazuay.com
Bus from Chiclayo to Cuenca
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $27–60
- Schedules at
- transportesazuay.com
Bus from Huaquillas to Cuenca
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $8–19
- Schedules at
- transportesazuay.com
Bus from Piura to Cuenca
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $21–50
- Schedules at
- transportesazuay.com
- Phone
- +51 511 418 1111
- contactcenter@civa.com.pe
- Website
- civa.com.pe
Bus from Lima Paseo de la República to Tumbes
- Ave. Duration
- 17h 40m
- Frequency
- Every 4 hours
- Estimated price
- $40–90
- Schedules at
- civa.com.pe
- Phone
- +51 1 311-5050
- Website
- cruzdelsur.com.pe
Bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 2d 7h
- Frequency
- Once daily
- Estimated price
- $100–170
- Website
- https://www.cruzdelsur.com.pe/home-en/
- Phone
- +51 994 656 518
- atencionalcliente@oltursa.com.pe
- Website
- oltursa.pe
Bus from Gran Terminal Terrestre Plaza Norte to Piura
- Ave. Duration
- 18h 46m
- Frequency
- Hourly
- Estimated price
- $40–60
- Website
- https://www.oltursa.pe/?lang=en
- Phone
- +51 997 598 289
- Website
- turismocavassa.com.pe
Bus from Gran Terminal Terrestre Plaza Norte to Piura
- Ave. Duration
- 15h
- Frequency
- Twice daily
- Estimated price
- $27–40
- Schedules at
- turismocavassa.com.pe
- Phone
- +51 1 4800725
- info@floreshnos.pe
- Website
- floreshnos.pe
Bus from Gran Terminal Terrestre Plaza Norte to Piura
- Ave. Duration
- 15h 15m
- Frequency
- Once daily
- Estimated price
- $23–40
- Schedules at
- floreshnos.pe
- Book at
- floreshnos.pe
- Phone
- +593 99 144 1474
- sanluisejecutivo@gmail.com
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $8–11
- Schedules at
- facebook.com
- Book at
- ecuabuses.com
- Phone
- +593 7-282-4005
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 4h 45m
- Frequency
- Every 30 minutes
- Estimated price
- $8–13
- Schedules at
- facebook.com
- Phone
- +593 98 453 6454
- semeriasa@yahoo.es
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 4h 15m
- Frequency
- Hourly
- Estimated price
- $9–35
- Book at
- redbus.pe
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 35m
- Frequency
- 5 times a day
- Estimated price
- $7–10
- Schedules at
- facebook.com
- Ave. Duration
- 3h 4m
- Estimated price
- $110–140
VIP Car
- Phone
- +593 9-9723-1913
- Website
- vipcar.com.ec
Ivan Car
- Phone
- +593 98 010 0100
- Website
- ivancar-ec.com
Auto Amigo
- Phone
- +593 99 317 1528
- Website
- facebook.com
Aeropuerto g y e taxis
- Phone
- +593 96 015 5142
- Website
- facebook.com
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Gatwick Airport into central London, Train travel in Spain: A guide to Renfe, and How to get from London to Edinburgh - to help you get the most out of your next trip.
More Questions & Answers
Yes, the driving distance between Santiago to Cuenca is 4669 km. It takes approximately 2 days 13h to drive from Santiago to Cuenca.
There are 451+ hotels available in Cuenca.






























