There are 6 ways to get from Santiago to Bolivia by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  6 h 11 min

  1. Fly from Santiago (SCL) to Santa Cruz (VVI) SCL - VVI

$191 - $693

Cheapest option

Bus  •  44 h 41 min

  1. Take the bus from Santiago - San Borja to Antofagasta Santiago
  2. Take the bus from Antofagasta to Santa Cruz

$61 - $142

4 alternative options

Bus via Teniente Luis Uribe / Sotomayor  •  41 h 46 min

  1. Take the bus from Santiago to Antofagasta
  2. Take the bus from Antofagasta to Santa Cruz

$73 - $123

Bus Turbus  •  2 days 6 h

  1. Take the bus from Santiago - Terminal San Borja to Calama Santiago
  2. Take the bus from Calama to Santa Cruz de la Sierra

$69 - $162

Bus Pluss Chile  •  2 days 6 h

  1. Take the bus from Santiago - San Borja to Calama Santiago
  2. Take the bus from Calama to Santa Cruz de la Sierra

$70 - $141

Drive  •  31 h 2 min

  1. Drive from Santiago to Santa Cruz de la Sierra 1556.8 miles

$250 - $380

Questions & Answers

No, there is no direct bus from Santiago to Bolivia. However, there are services departing from Santiago - Terminal San Borja and arriving at Santa Cruz - Ex Terminal via Calama and Santa Cruz Airport - El Trompillo. The journey, including transfers, takes approximately 2 days 6 h.

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The distance between Santiago and Bolivia is 1909 km. The road distance is 2490.9 km.

Get driving directions

The best way to get from Santiago to Bolivia without a car is to bus which takes 41 h 46 min and costs .

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It takes approximately 6 h 11 min to get from Santiago to Bolivia, including transfers.

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Santiago to Bolivia bus services, operated by Turbus, depart from Santiago - Terminal San Borja station.

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The best way to get from Santiago to Bolivia is to fly which takes 6 h 11 min and costs . Alternatively, you can bus, which costs and takes 41 h 46 min.

Mode details

The quickest flight from Santiago Airport to Santa Cruz Airport is the direct flight which takes 3 h 9 min.

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Santiago to Bolivia bus services, operated by Trans Salvador, arrive at Santa Cruz de la Sierra station.

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Yes, the driving distance between Santiago to Bolivia is 2491 km. It takes approximately 31 h 2 min to drive from Santiago to Bolivia.

Get driving directions

LATAM Chile and Aerolíneas Argentinas offer flights from Santiago Airport to Santa Cruz Airport.

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Map of how to get from Santiago to Bolivia.
Launch map view
  • Distance: 1193.3 miles
  • Duration: 6 h 11 min

What companies run services between Santiago, Chile and Bolivia?

LATAM Chile and Aerolíneas Argentinas fly from Santiago to Santa Cruz de la Sierra once daily. Alternatively, you can take a bus from Santiago to Santa Cruz de la Sierra via Antofagasta, Teniente Luis Uribe / Sotomayor, Paihuano / Av. Pedro Aguirre Cerda, Antofagasta, and Santa Cruz in around 41 h 46 min.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to Santa Cruz
Ave. Duration
3 h 9 min
When
Monday, Wednesday and Friday
Estimated price
$250 - $1,400
Aerolíneas Argentinas
Website
aerolineas.com.ar
Flights from Santiago to Santa Cruz via Buenos Aires Ministro Pistarini
Ave. Duration
6 h 10 min
When
Every day
Estimated price
$270 - $1,100
Bus operators
Trans Salvador
Phone
+56 58 222 8547
Email
central@trans-salvador.com
Website
trans-salvador.com
Bus from Antofagasta to Santa Cruz
Ave. Duration
25 h
Frequency
Twice daily
Estimated price
$40 - $75
Book at
ticketsbolivia.com.bo
Semi Bed
$40 - $55
Premium
$55 - $70
Bus from Calama to Santa Cruz de la Sierra
Ave. Duration
31 h 30 min
Frequency
3 times a week
Estimated price
$35 - $65
Schedules at
trans-salvador.com
Book at
ticketsbolivia.com.bo
Semi Bed
$35 - $50
Premium
$50 - $60
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Santiago - San Borja to Antofagasta
Ave. Duration
18 h 36 min
Frequency
Every 2 hours
Estimated price
$51
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Bus from Santiago - San Borja to Calama
Ave. Duration
22 h
Frequency
Every 2 hours
Estimated price
$51
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Expreso Norte
Website
expresonorte.cl
Bus from Santiago to Antofagasta
Ave. Duration
19 h
Frequency
Hourly
Estimated price
$45 - $65
Schedules at
expresonorte.cl
Book at
expresonorte.cl
Bus from Santiago - San Borja to Calama
Ave. Duration
21 h
Frequency
Twice daily
Estimated price
$30 - $75
Schedules at
expresonorte.cl
Semi Cama
$33
Cama
$68
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Santiago to Antofagasta
Ave. Duration
18 h 30 min
Frequency
Every 4 hours
Estimated price
$53
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Bus from Santiago to Calama
Ave. Duration
23 h 30 min
Frequency
Every 4 hours
Estimated price
$53
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Buses Evans
Website
busesevans.com
Bus from Santiago - Terminal San Borja to Antofagasta
Ave. Duration
14 h 55 min
Frequency
Once daily
Schedules at
busesevans.com
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Santiago to Antofagasta
Ave. Duration
17 h 50 min
Frequency
Once daily
Estimated price
$17 - $60
Schedules at
pullman.cl
Bus from Santiago to Calama
Ave. Duration
22 h 10 min
Frequency
Once daily
Estimated price
$50 - $75
Schedules at
pullman.cl
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Santiago - Terminal San Borja to Calama
Ave. Duration
21 h 10 min
Frequency
5 times a day
Estimated price
$30 - $100
Schedules at
turbus.cl
2nd Class
$30 - $70
Premium
$70 - $100
1st Class
$85 - $130

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More Questions & Answers

There are one+ hotels available in Bolivia. Prices start at $100 USD per night.

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The best way to get from Santiago to Santiago Airport is to Colectivo which takes 30 min and costs .

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