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There are 7 ways to get from Santiago de Cuba to Santa Clara by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Santiago to Havana, train  •  11 h 19 min

  1. Fly from Santiago (SCU) to Havana (HAV) SCU - HAV
  2. Take the train from Havana - La Coubre to Santa Clara

$143 - $352

Cheapest option

Train  •  11 h 1 min

  1. Take the train from Santiago de Cuba to Santa Clara

$25 - $40

5 alternative options

Fly Santiago to Camaguey, train  •  13 h 40 min

  1. Fly from Santiago (SCU) to Camaguey (CMW) SCU - CMW
  2. Take the train from Camaguey to Santa Clara

$253 - $1,037

Train to Holguin, fly to Havana, train  •  13 h 31 min

  1. Take the train from Santiago de Cuba to Cacocum
  2. Fly from Holguin (HOG) to Havana (HAV) HOG - HAV
  3. Take the train from Havana - La Coubre to Santa Clara

$138 - $501

Train to Manzanillo, fly to Santa Clara  •  6 h 5 min

  1. Take the train from Santiago de Cuba to Manzanillo
  2. Fly from Manzanillo (MZO) to Santa Clara (SNU) MZO - SNU

$64 - $224

Bus  •  12 h 20 min

  1. Take the bus from Santiago de Cuba to Santa Clara Via La Habana

$30 - $50

Drive  •  8 h 48 min

  1. Drive from Santiago de Cuba to Santa Clara 376.1 miles

Questions & Answers

The cheapest way to get from Santiago de Cuba to Santa Clara is to train which costs $25 - $40 and takes 11 h 1 min.

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The quickest way to get from Santiago de Cuba to Santa Clara is to train and fly which costs $60 - $230 and takes 6 h 5 min.

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Yes, there is a direct bus departing from Santiago de Cuba and arriving at Santa Clara. Services depart twice daily, and operate every day. The journey takes approximately 12 h 20 min.

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Yes, there is a direct train departing from Santiago de Cuba and arriving at Santa Clara. Services depart hourly. The journey takes approximately 11 h 1 min.

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The distance between Santiago de Cuba and Santa Clara is 504 km. The road distance is 601.7 km.

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The best way to get from Santiago de Cuba to Santa Clara without a car is to train which takes 11 h 1 min and costs $25 - $40.

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It takes approximately 11 h 19 min to get from Santiago de Cuba to Santa Clara, including transfers.

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Santiago de Cuba to Santa Clara bus services, operated by Viazul, depart from Santiago de Cuba station.

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Santiago de Cuba to Santa Clara train services, operated by Ferrocarriles de Cuba, depart from Santiago de Cuba station.

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The best way to get from Santiago de Cuba to Santa Clara is to train which takes 11 h 1 min and costs $25 - $40. Alternatively, you can bus, which costs $30 - $50 and takes 12 h 20 min.

Mode details

Map of how to get from Santiago de Cuba to Santa Clara.
Launch map view
  • Distance: 315.2 miles
  • Duration: 11 h 19 min

What companies run services between Santiago de Cuba and Santa Clara, Cuba?

Ferrocarriles de Cuba operates a train from Santiago de Cuba to Santa Clara on demand. Tickets cost $25 - $40 and the journey takes 11 h 1 min. Alternatively, Viazul operates a bus from Santiago de Cuba to Santa Clara twice daily. Tickets cost $30 - $50 and the journey takes 12 h 20 min.

Airlines
Cubana de Aviación
Website
cubana.cu
Flights from Santiago to Havana
Ave. Duration
1 h 31 min
When
Every day
Estimated price
$130 - $550
Flights from Santiago to Camaguey via Havana
Ave. Duration
8 h 25 min
When
Monday and Friday
Estimated price
$230 - $1,100
Flights from Holguin to Havana
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$110 - $650
Air Caraïbes
Website
aircaraibes.com
Flights from Santiago to Havana
Ave. Duration
1 h 27 min
When
Wednesday and Sunday
Estimated price
$130 - $420
Blue Panorama Airlines
Website
blue-panorama.com
Flights from Santiago to Havana
Ave. Duration
1 h 25 min
When
Monday
Estimated price
$70 - $300
Flights from Holguin to Havana
Ave. Duration
1 h 25 min
When
Saturday
Estimated price
$65 - $290
American Airlines
Website
aa.com
Flights from Santiago to Camaguey via Havana, Miami
Ave. Duration
7 h 55 min
When
Every day
Estimated price
$230 - $1,100
Sunwing Airlines
Website
sunwing.ca
Flights from Manzanillo to Santa Clara
Ave. Duration
1 h
When
Wednesday
Estimated price
$30 - $180
Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Havana - La Coubre to Santa Clara
Ave. Duration
7 h 30 min
Frequency
On demand
Estimated price
$6 - $10
Schedules at
seat61.com
Train from Camaguey to Santa Clara
Ave. Duration
4 h 52 min
Frequency
On demand
Estimated price
$10 - $16
Schedules at
seat61.com
Train from Santiago de Cuba to Cacocum
Ave. Duration
2 h 34 min
Frequency
On demand
Estimated price
$7 - $11
Schedules at
seat61.com
Train from Santiago de Cuba to Manzanillo
Ave. Duration
3 h 40 min
Frequency
On demand
Estimated price
$11 - $17
Schedules at
seat61.com
Train from Santiago de Cuba to Santa Clara
Ave. Duration
11 h 1 min
Frequency
On demand
Estimated price
$25 - $40
Schedules at
seat61.com
Bus operators
Viazul

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More Questions & Answers

The quickest flight from Santiago Airport to Havana Airport is the direct flight which takes 1 h 25 min.

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Santiago de Cuba to Santa Clara bus services, operated by Viazul, arrive at Santa Clara station.

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Santiago de Cuba to Santa Clara train services, operated by Ferrocarriles de Cuba, arrive at Santa Clara station.

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Yes, the driving distance between Santiago de Cuba to Santa Clara is 602 km. It takes approximately 8 h 48 min to drive from Santiago de Cuba to Santa Clara.

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Air Caraïbes, Blue Panorama Airlines and Cubana de Aviación offer flights from Santiago Airport to Havana Airport.

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There are 98+ hotels available in Santa Clara. Prices start at $23 USD per night.

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The best way to get from Santiago de Cuba to Santiago Airport is to line 212 bus which takes 24 min and costs .

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