Rome2rio uses cookies to help personalize content and show you personalised ads. By proceeding, you accept the use of cookies in accordance with our privacy policy. You may opt out of personalised ads at any time. OK

Need a hotel room in Brussels?

Book now

There are 2 ways to get from Santiago de Cuba to Brussels by train or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Holguin, fly  •  17h 14m

  1. Take the train from Santiago de Cuba to Cacocum
  2. Fly from Holguin (HOG) to Brussels (BRU) HOG - BRU

€254 - €618

Cheapest option

Fly from Santiago  •  18h 28m

  1. Fly from Santiago (SCU) to Brussels (BRU) SCU - BRU

€178 - €611

Santiago (SCU) to Brussels (BRU) flights

The flight time between Santiago (SCU) and Brussels (BRU) is around 18h 42m and covers a distance of around 7629 km. The fastest flight normally takes 15h 40m. Services are operated by Cubana de Aviación, Ryanair, Iberia and others. Typically 18 flights run weekly, although weekend and holiday schedules can vary so check in advance.

Flight route overview

Average flight journey time:
18h 42m
Fastest flight journey time:
15h 40m
Flight distance:
7629 km
Flights per week:
18
Cheapest price:
€103
Carbon emissions:
1547 kg CO2

First and last flights

First flight departs at:
11:05
Last flight departs at:
18:00

The schedules shown below are for the next available departures.

Santiago (SCU) to Brussels (BRU) flight schedules

Coronavirus (COVID-19) in Belgium

There is widespread community transmission globally.
Some travel restrictions are being lifted in Belgium. For the latest travel status, please check the official page for Belgium.

For travel planning advice, please refer to our Rome2rio Coronavirus information page .
For the latest travel status, we recommend checking the official page for Belgium.

Coronavirus (COVID-19) Travel Advice

Some international borders began to reopen in Belgium from June 15.

Official Coronavirus (COVID-19) Information for Belgium

Some domestic travel restrictions began to ease in Belgium from May 20.

Official Coronavirus (COVID-19) Information for Belgium

International flights leaving Cuba are suspended as part of the response to Coronavirus (COVID-19). Restrictions may also be in place for other modes of transport.

Last updated: August 4 | Data sourced from: ACAPS, OXFORD

Questions & Answers

The cheapest way to get from Santiago de Cuba to Brussels is to train and fly which costs $300 - $750 and takes 17h 14m.

More details

The quickest way to get from Santiago de Cuba to Brussels is to train and fly which costs $300 - $750 and takes 17h 14m.

More details

The distance between Santiago de Cuba and Brussels is 7615 km.

It takes approximately 17h 14m to get from Santiago de Cuba to Brussels, including transfers.

More details

There is no direct flight from Holguin Airport to Brussels Airport. The quickest flight takes 12h 35m and has one stopover.

Search flights

Brussels is 6h ahead of Santiago de Cuba. It is currently 1:28 PM in Santiago de Cuba and 7:28 PM in Brussels.

Condor Flugdienst, Lufthansa, Air Transat and two other airlines offer flights from Holguin Airport to Brussels Airport.

Search flights

There are 430+ hotels available in Brussels. Prices start at €87 per night.

More details

The best way to get from Santiago de Cuba to Santiago Airport is to line 212 bus which takes 24 min and costs $1 - $2.

More details

Map of how to get from Santiago de Cuba to Brussels.
Launch map view
  • Distance: 7615.4 km
  • Duration: 17h 14m

What companies run services between Santiago de Cuba and Brussels, Belgium?

Cubana de Aviación, Ryanair and 11 other airlines fly from Santiago de Cuba to Brussels 3 times a day.

Airlines
Air Canada
Website
aircanada.com
Flights from Holguin to Brussels via Montreal
Ave. Duration
13h 7m
When
Tuesday and Thursday
Estimated price
€250 - €650
Flights from Holguin to Brussels via Montreal, Frankfurt
Ave. Duration
15h
When
Thursday
Estimated price
€250 - €700
Flights from Holguin to Brussels via Frankfurt
Ave. Duration
12h 40m
When
Sunday
Estimated price
€300 - €850
Flights from Holguin to Brussels via Toronto, London Heathrow
Ave. Duration
16h 55m
When
Monday
Estimated price
€240 - €700
Flights from Holguin to Brussels via Montreal, London Heathrow
Ave. Duration
17h 50m
When
Thursday
Estimated price
€240 - €700
Flights from Santiago to Brussels via Madrid, Munich
Ave. Duration
18h 25m
When
Monday
Estimated price
€190 - €650
Brussels Airlines
Website
brusselsairlines.com
Flights from Holguin to Brussels via Frankfurt
Ave. Duration
12h 40m
When
Sunday
Estimated price
€300 - €850
Flights from Holguin to Brussels via Montreal
Ave. Duration
13h 40m
When
Tuesday
Estimated price
€250 - €650
Flights from Holguin to Brussels via Toronto, Paris CDG
Ave. Duration
14h 40m
When
Monday
Estimated price
€250 - €700
Flights from Holguin to Brussels via Montreal, Paris CDG
Ave. Duration
15h 35m
When
Thursday
Estimated price
€240 - €700
Lufthansa
Website
lufthansa.com
Flights from Holguin to Brussels via Frankfurt
Ave. Duration
12h 40m
When
Sunday
Estimated price
€300 - €850
Flights from Holguin to Brussels via Montreal
Ave. Duration
13h 40m
When
Tuesday
Estimated price
€250 - €650
Flights from Santiago to Brussels via Madrid, Munich
Ave. Duration
18h 25m
When
Monday
Estimated price
€190 - €650
Ryanair
Website
ryanair.com
Flights from Santiago to Brussels via Madrid
Ave. Duration
16h 25m
When
Monday
Estimated price
€170 - €600
Flights from Santiago to Brussels via Havana, Madrid
Ave. Duration
17h 25m
When
Tuesday
Estimated price
€200 - €700
Iberia
Website
iberia.com
Flights from Santiago to Brussels via Santo Domingo, Madrid
Ave. Duration
17h 40m
When
Monday, Wednesday and Friday
Estimated price
€220 - €700
Flights from Santiago to Brussels via Madrid, Barcelona
Ave. Duration
17h 25m
When
Monday
Estimated price
€180 - €650
Air Transat
Website
airtransat.com
Flights from Holguin to Brussels via Montreal
Ave. Duration
16h 25m
When
Thursday
Estimated price
€240 - €600
KLM
Website
klm.com
Flights from Santiago to Brussels via Madrid, Amsterdam Schiphol
Ave. Duration
17h 40m
When
Monday
Estimated price
€180 - €650
Air Europa
Website
aireuropa.com
Flights from Santiago to Brussels via Cancun, Madrid
Ave. Duration
19h 45m
When
Saturday
Estimated price
€250 - €650
Vueling Airlines
Website
vueling.com
Flights from Santiago to Brussels via Madrid, Barcelona
Ave. Duration
17h 25m
When
Monday
Estimated price
€180 - €650
Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Santiago de Cuba to Cacocum
Ave. Duration
2h 8m
Frequency
On demand
Estimated price
€1
Schedules at
thebusschedule.com
Old trains
€1
Second class
€1
First class
€1

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Italy Travel Guides, Is ride-sharing platform BlaBlaCar right for you? and Travelling to the UK: What do I need to know? - to help you get the most out of your next trip.