Explore 3 ways to travel

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  1 h 38 min

  1. SCL - LSC

$28 - $180

Cheapest option

Bus via Enea  •  7 h 7 min

  1. Santiago

$13 - $67

4 alternative options

Bus Andimar  •  7 h 22 min

  1. Santiago

$15 - $55

Bus Expreso Norte  •  7 h 35 min

$17 - $50

Bus via La Ligua  •  7 h 48 min

  1. Santiago
  2. Santiago

$16 - $90

Drive  •  4 h 35 min

  1. 299.2 miles

$45 - $75

What companies run services between Santiago Airport (SCL), Chile and La Serena, Chile?

LATAM Chile, Sky Airline and JetSMART fly from Santiago Airport (SCL) to La Serena every 4 hours. Alternatively, Turbus operates a bus from Santiago Airport (SCL) to La Serena hourly. Tickets cost $11 - $40 and the journey takes 5 h 55 min. Andimar also services this route every 3 hours.

Airlines
LATAM Chile
Website
latam.com
Flights from Santiago to La Serena
Ave. Duration
1 h 3 min
When
Every day
Estimated price
$120 - $600
Sky Airline
Website
skyairline.com
Flights from Santiago to La Serena
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$55 - $350
JetSMART
Website
jetsmart.com
Flights from Santiago to La Serena
Ave. Duration
1 h 5 min
When
Tuesday, Wednesday, Friday, Saturday and Sunday
Estimated price
$35 - $300
Bus operators
Turbus
Website
turbus.cl
Bus from Santiago to La Serena
Ave. Duration
5 h 55 min
Frequency
Hourly
Estimated price
$11 - $40
Schedules at
turbus.cl
2nd Class
$11 - $24
Premium
$28 - $40
1st Class
$28 - $45
Bus from Santiago to La Ligua
Ave. Duration
2 h
Frequency
Hourly
Estimated price
$4 - $21
Schedules at
turbus.cl
2nd Class
$4 - $11
Premium
$15 - $21
1st Class
$9 - $14
Bus from La Ligua to La Serena
Ave. Duration
3 h 35 min
Frequency
Once daily
Estimated price
$8 - $35
Schedules at
turbus.cl
2nd Class
$8 - $18
Premium
$22 - $35
1st Class
$19 - $28
Andimar
Website
andimar.cl
Bus from Santiago to La Serena
Ave. Duration
6 h
Frequency
Every 3 hours
Schedules at
andimar.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Santiago to La Serena
Ave. Duration
6 h 35 min
Frequency
Every 4 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Fichtur VIP
Phone
+56 (02) 7205232
Website
fichtur.cl
Bus from Santiago to La Serena
Ave. Duration
6 h 20 min
Frequency
4 times a day
Estimated price
$14
Schedules at
viajaenbus.cl
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Santiago to La Serena
Ave. Duration
6 h 20 min
Frequency
4 times a day
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Buses Serena Mar
Phone
+56 94 915 6683
Website
serenamar.cl
Bus from Santiago to La Serena
Ave. Duration
6 h
Frequency
Twice daily
Estimated price
$24
Schedules at
serenamar.cl
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Santiago to La Serena
Ave. Duration
5 h 44 min
Frequency
Once daily
Estimated price
$17 - $23
Schedules at
pullman.cl
Condor Bus
Phone
2680 6900
Website
condorbus.cl
Bus from Santiago - Alameda Terminal to La Ligua
Ave. Duration
1 h 35 min
Frequency
3 times a day
Estimated price
$7 - $40
Schedules at
condorbus.cl
Semi Bed
$12 - $18
Suite
$32 - $36

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Slovenia: Getting from Ljubljana to Lake Bled, Heading to Europe? Read this before you buy a Eurail Pass and Train travel in France: A guide to SNCF - to help you get the most out of your next trip.

Questions & Answers

The distance between Santiago Airport (SCL) and La Serena is 391 km. The road distance is 479 km.

The cheapest way to get from Santiago Airport (SCL) to La Serena is to bus which costs $16 - $50 and takes 7 h 35 min.

The quickest way to get from Santiago Airport (SCL) to La Serena is to fly which takes 1 h 38 min and costs $28 - $180.

No, there is no direct bus from Santiago Airport (SCL) to La Serena. However, there are services departing from Santiago Airport and arriving at La Serena via Enea and Santiago. The journey, including transfers, takes approximately 7 h 7 min.

It takes approximately 1 h 38 min to get from Santiago Airport (SCL) to La Serena, including transfers.