There are 10 ways to get from Santander to Sicily by plane, car, car ferry, bus, or train (Renfe, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Santander Airport to Palermo Airport
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)SDR - PMO
8h 45m€66–289Drive, car ferry
- Drive from Santander to Port of Genoa
- Take the car ferry from Port of Genoa to Port of Palermo
33h 6m€266–430Bus via Bordeaux
- Take the bus from Santander to Bordeaux
- Take the bus from Bordeaux to Florence Villa Constanza Bus Station
- Take the bus from Florence Villa Constanza Bus Station to Palermo
43h 9m€122–304Train
- Take the train from Santander to Madrid ChamartínAlv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Take the train from Marseille St Charles to Roma Termini
- Take the train from Roma Termini to Palermo CentraleIc
43h 58m€291–606Bus to Bilbao Airport, fly to Palermo Airport
- Take the bus from Santander E.A. to Bilbao Intermodal
- Fly from Bilbao Airport (BIO) to Palermo Airport (PMO)BIO - PMO
7h 33m€82–250Bus to Bilbao Airport, fly to Catania–Fontanarossa Airport
- Take the bus from Santander E.A. to Bilbao Intermodal
- Fly from Bilbao Airport (BIO) to Catania–Fontanarossa Airport (CTA)BIO - CTA
9h 10m€75–268Fly Santander Airport to Catania–Fontanarossa Airport
- Fly from Santander Airport (SDR) to Catania–Fontanarossa Airport (CTA)SDR - CTA
7h 27m€134–557Bus, bus to Vitoria-Gasteiz Airport, fly to Palermo Airport
- Take the bus from Santander E.A. to Bilbao Intermodal
- Take the bus from Bilbao Bolueta to Aireportua/Aeropuerto Vitoria-Gasteiz
- Fly from Vitoria-Gasteiz Airport (VIT) to Palermo Airport (PMO)VIT - PMO
15h 13m€98–315Bus, car ferry
- Take the bus from Santander E.A. to Bilbao Intermodal
- Take the bus from Bilbao to Nice Airport
- Take the bus from Nice Airport to Genoa798 / ...
- Take the car ferry from Port of Genoa to Port of Palermo
45h 49m€145–334Bus
- Take the bus from Santander E.A. to Vitoria-Gasteiz
- Take the bus from Vitoria Gasteiz Central Bus Station to Milano, Autostazione Lampugnano
- Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazello
2d 2h€126–192
Santander to Sicily by bus
Questions & Answers
The cheapest way to get from Santander to Sicily is to bus and fly which costs €75 - €270 and takes 9h 10m.
The fastest way to get from Santander to Sicily is to fly which takes 7h 27m and costs €130 - €600.
No, there is no direct bus from Santander to Sicily. However, there are services departing from Santander and arriving at Piazza Boiardo via Bordeaux, Florence Villa Constanza Bus Station and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 43h 9m.
No, there is no direct train from Santander to Sicily. However, there are services departing from Santander and arriving at Palermo Notarbartolo via Madrid Chamartín, Madrid-Puerta de Atocha-Almudena Grandes, Marseille St Charles, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 43h 58m.
The distance between Santander and Sicily is 1573 km.
The best way to get from Santander to Sicily without a car is to bus via Bordeaux which takes 43h 9m and costs €120 - €310.
It takes approximately 8h 45m to get from Santander to Sicily, including transfers.
Santander to Sicily bus services, operated by FlixBus, depart from Santander station.
Santander to Sicily train services, operated by Renfe Viajeros, depart from Santander station.
The best way to get from Santander to Sicily is to fly which takes 8h 45m and costs €65 - €290. Alternatively, you can bus via Bordeaux, which costs €120 - €310 and takes 43h 9m, you could also train, which costs €290 - €650 and takes 43h 58m.
What companies run services between Santander, Spain and Sicily, Italy?
Vueling Airlines, Iberia, and Ryanair fly from Santander Airport (SDR) to Palermo Airport (PMO) 6 times a week. Alternatively, you can take a bus from Santander to Piazza Boiardo via Bordeaux, Florence Villa Constanza Bus Station, Palermo, and Stazione Centrale Pensilina Esterna in around 43h 9m.
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via London Stansted
- Ave. Duration
- 10h 20m
- When
- Thursday
- Estimated price
- €100–300
Flights from Santander Airport to Palermo Airport via Charleroi
- Ave. Duration
- 12h
- When
- Monday
- Estimated price
- €95–300
Flights from Bilbao Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 5h 40m
- When
- Monday and Sunday
- Estimated price
- €30–200
Flights from Bilbao Airport to Catania–Fontanarossa Airport via Milan Malpensa
- Ave. Duration
- 5h 35m
- When
- Friday
- Estimated price
- €75–190
Flights from Vitoria-Gasteiz Airport to Palermo Airport via Charleroi
- Ave. Duration
- 9h
- When
- Friday
- Estimated price
- €90–290
Flights from Vitoria-Gasteiz Airport to Palermo Airport via Milan Bergamo
- Ave. Duration
- 10h 45m
- When
- Friday
- Estimated price
- €80–270
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 30m
- When
- Monday and Saturday
- Estimated price
- €60–280
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 10h 10m
- When
- Monday and Thursday
- Estimated price
- €90–350
Flights from Bilbao Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 20m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €75–220
Flights from Santander Airport to Catania–Fontanarossa Airport via Madrid
- Ave. Duration
- 4h 50m
- When
- Tuesday and Wednesday
- Estimated price
- €95–340
Flights from Vitoria-Gasteiz Airport to Palermo Airport via Madrid
- Ave. Duration
- 8h 35m
- When
- Monday and Thursday
- Estimated price
- €85–330
- Website
- vueling.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 30m
- When
- Monday and Saturday
- Estimated price
- €60–280
Flights from Bilbao Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 20m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €75–220
- Website
- volotea.com
Flights from Bilbao Airport to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Saturday
- Estimated price
- €50–110
- Website
- easyjet.com
Flights from Bilbao Airport to Catania–Fontanarossa Airport via Milan Malpensa
- Ave. Duration
- 5h 45m
- When
- Thursday
- Estimated price
- €45–180
- Website
- flexflight.dk
Flights from Bilbao Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 5h 50m
- When
- Wednesday
- Estimated price
- €65–150
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 16m
- Frequency
- 3 times a day
- Estimated price
- €35–85
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 14m
- Frequency
- 5 times a week
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Marseille St Charles to Roma Termini
- Ave. Duration
- 16h 2m
- Frequency
- Once a week
- Estimated price
- €120–280
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 36m
- Frequency
- Once daily
- Estimated price
- €40–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Santander to Bordeaux
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €25–70
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- 5 times a week
- Estimated price
- €60–140
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h 15m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- https://www.flixbus.co.uk
Bus from Santander E.A. to Bilbao Intermodal
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- €10–15
- Website
- https://www.flixbus.co.uk
Bus from Bilbao to Nice Airport
- Ave. Duration
- 16h 55m
- Frequency
- 3 times a week
- Estimated price
- €60–150
- Website
- https://www.flixbus.co.uk
Bus from Nice Airport to Genoa
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €10–20
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Once a week
- Estimated price
- €35–55
- Schedules at
- autoservizisalemi.it
Bus from Milano, San Donato M3 to Palermo Via Tommaso Fazello
- Ave. Duration
- 21h
- Frequency
- Once a week
- Estimated price
- €50–75
- Schedules at
- autoservizisalemi.it
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–22
- Website
- https://www.alsa.com/en/
Bus from Santander E.A. to Vitoria-Gasteiz
- Ave. Duration
- 2h 25m
- Frequency
- 3 times a day
- Estimated price
- €12–15
- Website
- https://www.alsa.com/en/
- Phone
- +34 94 476 50 07
- Website
- autobuseslaunion.com
Bus from Bilbao Bolueta to Aireportua/Aeropuerto Vitoria-Gasteiz
- Ave. Duration
- 55 min
- Frequency
- Every 3 hours
- Estimated price
- €5–15
- Website
- https://www.autobuseslaunion.com/en
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Vitoria Gasteiz Central Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 23h 30m
- Frequency
- Twice a week
- Estimated price
- €60–95
- Website
- https://union-ivkoni.com/en
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €65–140
- Website
- https://www.gnv.it/en
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More Questions & Answers
Santander to Sicily bus services, operated by FlixBus, arrive at Bordeaux station.
Santander to Sicily train services, operated by Renfe Viajeros, arrive at Madrid Chamartín station.
Book your Santander to Sicily train tickets online with Omio.
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