There are 7 ways to get from Santander to Setúbal by plane, bus, train, car, or train (Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Santander Airport (SDR) to Lisbon-Portela Airport (LIS)SDR - LIS
- Take the bus from Estação Rodoviária de Lisboa Oriente to Setúbal
4h 27m€85–225Bus via Setúbal
cheapest- Take the bus from Santander E.A. to Bilbao Intermodal
- Take the bus from Bilbao Intermodal to Estação Rodoviária de Lisboa Oriente
- Take the bus from Estação Rodoviária de Lisboa Oriente to Setúbal
16h 27m€41–141Train, bus
- Take the train from Santander to Madrid ChamartínAlv / ...
- Take the train from Madrid Chamartín to BadajozAlv
- Take the bus from Badajoz to Setúbal
13h 26mBus
- Take the bus from Santander E.A. to Bilbao Intermodal
- Take the bus from Bilbao to Lisbon
- Take the bus from Estação Rodoviária de Lisboa Oriente to Avenida Dom João II
14h 14m€76–116Drive 840.6 km
- Drive from Santander to Setúbal840.6 km
8h 32m€132–190Bus, train
- Take the bus from Santander to Porto
- Take the train from Porto Campanha to Lisboa OrienteIc / ...
- Take the bus from Estação Rodoviária de Lisboa Oriente to Setúbal
15h 15m€55–109Train
- Take the train from Santander to Madrid ChamartínAlv / ...
- Take the train from Madrid Chamartín to BadajozAlv
- Take the train from Badajoz to EntroncamentoRe
- Take the train from Entroncamento to Lisboa OrienteRe / ...
- Take the train from Sete-Rios to Setúbal
16h 47m€95–203
Santander Airport (SDR) to Lisbon-Portela Airport (LIS) flights
Questions & Answers
The cheapest way to get from Santander to Setúbal is to bus and train which costs €55 - €110 and takes 15h 15m.
The fastest way to get from Santander to Setúbal is to fly and bus which takes 4h 27m and costs €80 - €230.
No, there is no direct bus from Santander to Setúbal. However, there are services departing from Santander E.A. and arriving at Avenida Dom João II via Bilbao and Estação Rodoviária de Lisboa Oriente. The journey, including transfers, takes approximately 14h 14m.
No, there is no direct train from Santander to Setúbal. However, there are services departing from Santander and arriving at Setúbal via Madrid Chamartín, Badajoz, Entroncamento, Lisboa Oriente and Sete-Rios. The journey, including transfers, takes approximately 16h 47m.
The distance between Santander and Setúbal is 730 km. The road distance is 840.6 km.
The best way to get from Santander to Setúbal without a car is to train and bus which takes 13h 26m and costs .
It takes approximately 4h 27m to get from Santander to Setúbal, including transfers.
Santander to Setúbal bus services, operated by ALSA, depart from Santander E.A. station.
Santander to Setúbal train services, operated by Renfe Viajeros, depart from Santander station.
The best way to get from Santander to Setúbal is to bus which takes 14h 14m and costs €75 - €120. Alternatively, you can train, which costs €95 - €210 and takes 16h 47m.
What companies run services between Santander, Spain and Setúbal, Portugal?
You can take a bus from Santander E.A. to Avenida Dom João II via Bilbao Intermodal, Bilbao, and Estação Rodoviária de Lisboa Oriente in around 14h 14m. Alternatively, you can take a train from Santander to Setúbal via Madrid Chamartín, Badajoz, Entroncamento, Lisboa Oriente, Sete Rios, and Sete-Rios in around 16h 47m.
- Website
- iberia.com
Flights from Santander Airport to Lisbon-Portela Airport via Madrid
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €95–200
Flights from Santander Airport to Lisbon-Portela Airport via Barcelona
- Ave. Duration
- 5h 30m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- €50–210
- Website
- flytap.com
Flights from Santander Airport to Lisbon-Portela Airport via Valencia
- Ave. Duration
- 5h 5m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €75–270
Flights from Santander Airport to Lisbon-Portela Airport via Malaga
- Ave. Duration
- 5h 25m
- When
- Monday and Saturday
- Estimated price
- €90–200
Flights from Santander Airport to Lisbon-Portela Airport via Sevilla
- Ave. Duration
- 5h 55m
- When
- Monday, Wednesday, and Sunday
- Estimated price
- €65–270
- Website
- vueling.com
Flights from Santander Airport to Lisbon-Portela Airport via Madrid
- Ave. Duration
- 3h 25m
- When
- Saturday and Sunday
- Estimated price
- €95–200
Flights from Santander Airport to Lisbon-Portela Airport via Barcelona
- Ave. Duration
- 5h 30m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- €50–210
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- Twice daily
- Estimated price
- €30–85
- Website
- https://www.renfe.com/es/en
Train from Madrid Chamartín to Badajoz
- Ave. Duration
- 4h 39m
- Frequency
- 3 times a day
- Estimated price
- €35–70
- Website
- https://www.renfe.com/es/en
- Phone
- +351 210 900 032
- Website
- cp.pt
Train from Porto Campanha to Lisboa Oriente
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.cp.pt/passageiros/en
Train from Badajoz to Entroncamento
- Ave. Duration
- 2h 45m
- Frequency
- Twice daily
- Estimated price
- €14
- Website
- https://www.cp.pt/passageiros/en
Train from Entroncamento to Lisboa Oriente
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €8–20
- Website
- https://www.cp.pt/passageiros/en
- Phone
- +351 211 066 363
- info@fertagus.pt
- Website
- fertagus.pt
Train from Sete-Rios to Setúbal
- Ave. Duration
- 52 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Website
- https://www.fertagus.pt/en
Bus from Estação Rodoviária de Lisboa Oriente to Setúbal
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Estação Rodoviária de Lisboa Oriente to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
- Website
- blablacar.co.uk
Bus from Badajoz to Setúbal
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Schedules at
- blablacar.co.uk
Bus from Bilbao to Lisbon
- Ave. Duration
- 11h 15m
- Frequency
- Twice daily
- Schedules at
- blablacar.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- https://www.alsa.com/en/
Bus from Bilbao Intermodal to Estação Rodoviária de Lisboa Oriente
- Ave. Duration
- 13h
- Frequency
- Twice daily
- Estimated price
- €30–120
- Website
- https://www.alsa.com/en/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Bilbao to Lisbon
- Ave. Duration
- 10h 50m
- Frequency
- Twice daily
- Estimated price
- €65–95
- Website
- https://www.flixbus.co.uk
Bus from Santander to Porto
- Ave. Duration
- 10h 50m
- Frequency
- Once daily
- Estimated price
- €35–70
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Portugal
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Train travel in Spain: A guide to Renfe
Read the travel guide
What are the different types of Renfe trains in Spain?
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Santander to Setúbal bus services, operated by ALSA, arrive at Bilbao Intermodal station.
Setúbal is 1h behind Santander. It is currently 2:07 AM in Santander and 1:07 AM in Setúbal.
Santander to Setúbal train services, operated by Renfe Viajeros, arrive at Madrid Chamartín station.
Yes, the driving distance between Santander to Setúbal is 841 km. It takes approximately 8h 32m to drive from Santander to Setúbal.
Book your Santander to Setúbal bus tickets online with Omio.
There are 1298+ hotels available in Setúbal.





























