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  • Deutsche Bahn
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There are 7 ways to get from Santander to Rome by bus, plane, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, fly  •  6 h 52 min

  1. Take the bus from Santander to Bilbao
  2. Fly from Bilbao (BIO) to Rome (FCO) BIO - FCO

$91 - $327

6 alternative options

Train  •  25 h 38 min

  1. Take the train from Santander to Madrid-Chamartin A
  2. Take the train from Madrid-Puerta de Atocha to Marseille-St-Charles Ave
  3. Take the train from Marseille-Saint-Charles to Milano Centrale Ec
  4. Take the train from Milano Centrale to Roma Termini Fr

$293 - $464

Bus, train  •  26 h 24 min

  1. Take the bus from Santander to Sion
  2. Take the train from Sion to Milano Centrale Ec
  3. Take the train from Milano Centrale to Roma Termini Fr

$178 - $339

Bus Eurolines CH  •  28 h 45 min

  1. Take the bus from Santander to Genève
  2. Take the bus from Geneva to Rome N1729

$140 - $249

Bus Eurolines FR  •  38 h 50 min

  1. Take the bus from Santander to Bordeaux
  2. Take the bus from Bordeaux to Roma

$218 - $314

Bus ALSA  •  2 days 8 h

  1. Take the bus from Santander to Zaragoza
  2. Take the bus from Zaragoza to Roma

$154 - $240

Drive  •  17 h 11 min

  1. Drive from Santander to Rome 1125.3 miles

$270 - $400

Questions & Answers

The cheapest way to get from Santander to Rome is to bus and fly which costs 75€ - 290€ and takes 6 h 52 min.

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The quickest way to get from Santander to Rome is to bus and fly which costs 75€ - 290€ and takes 6 h 52 min.

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No, there is no direct bus from Santander to Rome. However, there are services departing from Santander and arriving at Rome via Geneva. The journey, including transfers, takes approximately 28 h 45 min.

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No, there is no direct train from Santander to Rome. However, there are services departing from Santander and arriving at Roma Termini via Madrid Chamartín, Madrid-Puerta de Atocha, Marseille-Saint-Charles and Milano Centrale. The journey, including transfers, takes approximately 25 h 38 min.

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The distance between Santander and Rome is 1342 km. The road distance is 1800.5 km.

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The best way to get from Santander to Rome without a car is to train which takes 25 h 38 min and costs 250€ - 410€.

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It takes approximately 6 h 52 min to get from Santander to Rome, including transfers.

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Santander to Rome bus services, operated by Eurolines FR, depart from Santander station.

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Santander to Rome train services, operated by Spanish Railways (RENFE), depart from Santander station.

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The best way to get from Santander to Rome is to train which takes 25 h 38 min and costs 250€ - 410€. Alternatively, you can bus, which costs 120€ - 220€ and takes 28 h 45 min.

Mode details

Map of how to get from Santander to Rome.
Launch map view
  • Distance: 838.7 miles
  • Duration: 6 h 52 min

What companies run services between Santander, Spain and Rome, Italy?

You can take a train from Santander to Rome via Madrid-Chamartin, Madrid Chamartín, Madrid Atocha, Madrid-Puerta de Atocha, Marseille-St-Charles, Marseille-Saint-Charles, and Milano Centrale in around 25 h 38 min. Alternatively, you can take a bus from Santander to Rome via Geneva in around 28 h 45 min.

Airlines
Iberia
Website
iberia.com
Flights from Bilbao to Rome
Ave. Duration
2 h 10 min
When
Wednesday and Saturday
Estimated price
$90 - $600
Flights from Bilbao to Rome via Barcelona
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$90 - $600
Flights from Bilbao to Rome via Madrid
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$90 - $500
Flights from Bilbao to Rome via Valencia
Ave. Duration
4 h
When
Monday, Wednesday and Friday
Estimated price
$90 - $600
Vueling Airlines
Website
vueling.com
Flights from Bilbao to Rome
Ave. Duration
2 h 10 min
When
Wednesday and Saturday
Estimated price
$90 - $600
Flights from Bilbao to Rome via Barcelona
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$90 - $600
Lufthansa
Website
lufthansa.com
Flights from Bilbao to Rome via Munich
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$220 - $700
Flights from Bilbao to Rome via Frankfurt
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$220 - $700
Brussels Airlines
Website
brusselsairlines.com
Flights from Bilbao to Rome via Brussels
Ave. Duration
4 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$95 - $700
Air France
Website
airfrance.com
Flights from Bilbao to Rome via Paris CDG
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$150 - $1,100
Eurowings
Website
eurowings.com
Flights from Bilbao to Rome via Dusseldorf
Ave. Duration
5 h
When
Monday to Friday
Estimated price
$280 - $1,000
Air Europa
Website
aireuropa.com
Flights from Bilbao to Rome via Madrid
Ave. Duration
5 h
When
Every day
Estimated price
$110 - $550
Train operators
Spanish Railways (RENFE)

Based in Madrid, Renfe is a state-owned train operator, that connects cities across Spain and neighbouring countries including Portugal, France, Germany, Switzerland, and the Netherlands. Renfe’s extensive network means most destinations offer multiple trains a day, with the most popular routes normally offering a train each hour. Locally known as AVE, the high-speed trains can reach speeds of up to 350km/h, making travel between major cities very efficient. Comfort is key in a Renfe train, with seats with footrests in all three classes of travel: Standard, Club and First. Each seat has an individual light, a pull-down table and an electrical outlet for in Club and First classes. There is free WiFi for first class passengers and for those with a + Renfe card.

Rome2rio's guide to Spanish Railways (RENFE)
Contact Details
Phone
902 320 320
Website
renfe.com
Train from Santander to Madrid-Chamartin
Ave. Duration
4 h 20 min
Frequency
5 times a day
Estimated price
$50 - $65
Website
renfe.com
Spanish Railways AVE
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Marseille-Saint-Charles to Milano Centrale
Ave. Duration
7 h 28 min
Frequency
Once daily
Estimated price
$80 - $110
Website
orario.trenitalia.com
Train from Sion to Milano Centrale
Ave. Duration
2 h 24 min
Frequency
4 times a day
Estimated price
$35 - $55
Website
orario.trenitalia.com
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Milano Centrale to Roma Termini
Ave. Duration
3 h 20 min
Frequency
Hourly
Estimated price
$55 - $85
Website
orario.trenitalia.com
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Milano Centrale Station to Roma Termini Station
Ave. Duration
3 h 30 min
Frequency
Hourly
Estimated price
$30 - $45
Website
italotreno.it
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Sion to Milano Centrale
Ave. Duration
2 h 22 min
Frequency
Every 4 hours
Estimated price
$45 - $75
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
ALSA

A Spanish subsidiary of National Express, ALSA provides bus and coach services across Spain and neighbouring countries including Portugal, France, Germany, the Netherlands, Italy, Poland and Malta. Founded in 1923, ALSA values service and the customer experience. Buses are equipped with communal TV screens showing movies, individual behind-seat screens, ALSA radio, app for books and music, and free WiFi so you’re never bored on your journey. ALSA services are accessible to people with disabilities, and guide dogs are welcome on all journeys. Flexibility is another highlight of an ALSA journey, with three types of tickets on offer - Frequent Traveller Pass, Share Pass and ALSA Pass, along with discounts for senior citizens, students and children.

Contact Details
Phone
+34 902 42 22 42
Website
alsa.es
Bus from Santander to Bilbao
Ave. Duration
1 h 30 min
Frequency
Hourly
Estimated price
$18 - $28
Website
alsa.com
Bus from Santander to Zaragoza
Ave. Duration
5 h 30 min
Frequency
5 times a day
Estimated price
$30 - $50
Website
alsa.com
Bus from Zaragoza to Roma
Ave. Duration
2 days 1 h
Frequency
Once daily
Estimated price
$120 - $190
Website
alsa.com
Eurolines CH
Phone
0041 (0) 844 257 224
Website
eurolines.ch
Bus from Santander to Sion
Ave. Duration
19 h 29 min
Frequency
3 times a week
Estimated price
$90 - $170
Book at
eurolines.ch
Bus from Santander to Genève
Ave. Duration
17 h 45 min
Frequency
3 times a week
Estimated price
$85 - $170
Book at
eurolines.ch
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Geneva to Rome
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$50 - $85
Website
flixbus.co.uk
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Santander to Bordeaux
Ave. Duration
6 h 15 min
Frequency
3 times a week
Estimated price
$65 - $95
Schedules at
eurolines.fr
Bus from Bordeaux to Roma
Ave. Duration
31 h 35 min
Frequency
Once a week
Estimated price
$150 - $220
Schedules at
eurolines.fr

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Bilbao Airport to Rome Airport is the direct flight which takes 2 h 10 min.

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Santander to Rome bus services, operated by Eurolines FR, arrive at Roma station.

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Santander to Rome train services, operated by Trenitalia Frecce, arrive at Roma Termini station.

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Yes, the driving distance between Santander to Rome is 1801 km. It takes approximately 17 h 11 min to drive from Santander to Rome.

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Brussels Airlines, Air France, Eurowings and four other airlines offer flights from Bilbao Airport to Rome Airport.

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Book your Santander to Rome bus tickets online with Busbud and Busbud.

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There are 11718+ hotels available in Rome. Prices start at $51 USD per night.

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