Rome2Rio

How to get fromSantander to Romeby plane, bus, train, or car

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There are 6 ways to get from Santander to Rome by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Santander Airport (SDR) to Fiumicino International Airport (FCO)plane plane SDR - FCO
    4h 42m
    €69–218

  2. Bus, train via Antony

    1. Take the bus from Estación de autobuses de Santander to Estación de Autobuses Donostia-San Sebastiánbus bus
    2. Take the train from Hendaye to Massy Tgvtrain train Tgv
    3. Take the train from Massy Tgv to Modanetrain train Tgv
    4. Take the train from Modane to Milano Centraletrain train Fr
    5. Take the train from Milano Centrale to Roma Terminitrain train
    21h 38m
    €387–610

  3. Bus

    1. Take the bus from Estación de autobuses de Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus bus 510 / ...
    27h 58m
    €161–260

  4. Drive  1,773.6 km

    1. Drive from Santander to Romecar car 1,773.6 km
    17h 6m
    €289–417

  5. Bus, train

    1. Take the bus from Estación de autobuses de Santander to Padovabus bus
    2. Take the train from Padova to Roma Terminitrain train Fr
    29h 17m
    €171–255

  6. Bus via Lyon

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Lyon - Gerland Bus Stationbus bus
    3. Take the bus from Lyon Lyon Perrache Bus Station to Rome Tiburtina Largo Mazzonibus bus
    33h
    €124–218

Santander to Rome by bus

Calendar5Weekly Buses
Duration27h 58mAverage Duration
Ticket€161Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santander to Rome.ExpandLaunch map view
  • Distance: 1,357.5 km
  • Duration: 4h 42m

What companies run services between Santander, Spain and Rome, Italy?

Vueling Airlines, Iberia, and two other airlines fly from Santander Airport (SDR) to Fiumicino International Airport (FCO) 3 times a day. Alternatively, you can take a bus from Estación de autobuses de Santander to Roma, Autostazione Tiburtina via Bordeaux and Florence Villa Constanza Bus Station in around 27h 58m.

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Want to know more about travelling around Italy

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