There are 7 ways to get from Santander to Pisa by plane, train, ferry, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane SDR - FLR
- Take the train from Firenze S.M.N. to Pisa Centraletrain
7h 10m€79–317Fly to Pisa International Airport
cheapest- Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane SDR - PSA
4h 30m€55–300Train, ferry
- Take the train from Santander to Madrid Chamartíntrain Alv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Genoaferry
- Take the train from Genova P.Za Principe to Pisa Centraletrain Fb / ...
25h 5m€194–393Bus, train via Nice Airport (NCE)
- Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus
- Take the bus from Bilbao to Nice Airportbus
- Take the train from Nice Saint-Augustin to Ventimigliatrain C3
- Take the train from Ventimiglia to Pisa Centraletrain Ic
26h 8m€146–239Drive 1,434.7 km
- Drive from Santander to Pisacar 1,434.7 km
14h 4m€258–373Bus
- Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus
- Take the bus from Bilbao to Nice Airportbus
- Take the bus from Nice Airport to Pisabus
26h 10m€134–213Bus, train
- Take the bus from Estación de autobuses de Santander to Padovabus
- Take the train from Padova to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Pisa Centraletrain Re
29h 3m€155–208
Santander to Pisa by bus, tram, and train
Comparing Your Travel Options
The cheapest way to get from Santander to Pisa is to fly and train which costs €75 - €320 and takes 7h 10m.
The fastest way to get from Santander to Pisa is to fly which takes 4h 30m and costs €55 - €300.
No, there is no direct bus from Santander to Pisa. However, there are services departing from Estación de autobuses de Santander and arriving at Pisa via Bilbao and Nice Airport. The journey, including transfers, takes approximately 26h 10m.
The distance between Santander and Pisa is 1292 km. The road distance is 1434.7 km.
The best way to get from Santander to Pisa without a car is to train and ferry which takes 25h 5m and costs €190 - €400.
It takes approximately 7h 10m to get from Santander to Pisa, including transfers.
Santander to Pisa bus services, operated by ALSA, depart from Estación de autobuses de Santander station.
The best way to get from Santander to Pisa is to fly which takes 4h 30m and costs €55 - €300. Alternatively, you can bus, which costs €130 - €220 and takes 26h 10m.
There is no direct flight from Santander Airport Airport to Pisa International Airport Airport. The quickest flight takes 4h 50m and has one stopover.
Santander to Pisa bus services, operated by ALSA, arrive at Bilbao Intermodal station.
What companies run services between Santander, Spain and Pisa, Italy?
Ryanair, Vueling Airlines, and four other airlines fly from Santander Airport (SDR) to Pisa International Airport (PSA) twice daily. Alternatively, you can take a bus from Estación de autobuses de Santander to Pisa via Bilbao Intermodal, Bilbao, and Nice Airport in around 26h 10m.
- Website
- iberia.com
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 7h 6m
- When
- Monday, Friday, Tuesday, Thursday, and Sunday
- Estimated price
- €65–470
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 8h 12m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €65–240
- Website
- vueling.com
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 7h 6m
- When
- Monday, Friday, Tuesday, Thursday, and Sunday
- Estimated price
- €65–470
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 8h 12m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €65–240
- Website
- ryanair.com
Flights from Santander Airport to Pisa International Airport via London Stansted
- Ave. Duration
- 4h 50m
- When
- Wednesday and Saturday
- Estimated price
- €90–350
Flights from Santander Airport to Pisa International Airport via Madrid
- Ave. Duration
- 4h 50m
- When
- Friday and Sunday
- Estimated price
- €75–320
Flights from Santander Airport to Pisa International Airport via Valencia
- Ave. Duration
- 6h 5m
- When
- Monday
- Estimated price
- €75–320
- Website
- easyjet.com
Flights from Santander Airport to Pisa International Airport via Paris Orly
- Ave. Duration
- 4h 30m
- When
- Wednesday
- Estimated price
- €80–360
- Website
- flyulendo.com
Flights from Santander Airport to Pisa International Airport via Madrid
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- €55–300
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 3h 32m
- Frequency
- Twice a week
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h
- Frequency
- 5 times a day
- Estimated price
- €50–80
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €80–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €50–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €40–70
- Website
- Ouigo
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 1h 57m
- Frequency
- Every 2 hours
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €29–50
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
Train from Ventimiglia to Pisa Centrale
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
- Phone
- +33 4 13 94 30 50
- Website
- ZOU!
Train from Nice Saint-Augustin to Ventimiglia
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Schedules at
- ZOU!
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Nice Saint-Augustin to Ventimiglia
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €10–14
- Website
- Zou! Lignes Express Régionales
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €25–45
- Website
- Italo Treno
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Estación de autobuses de Santander to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
Bus from Estación de autobuses de Santander to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Bilbao to Nice Airport
- Ave. Duration
- 16h 45m
- Frequency
- 3 times a week
- Estimated price
- €95–150
- Website
- Flixbus
Bus from Bilbao to Nice Airport
- Ave. Duration
- 16h 45m
- Frequency
- 3 times a week
- Estimated price
- €95–150
- Website
- Flixbus
Bus from Nice Airport to Pisa
- Ave. Duration
- 5h 55m
- Frequency
- 5 times a week
- Estimated price
- €30–50
- Website
- Flixbus
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Estación de autobuses de Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €120–150
- Schedules at
- tabitatour.ro
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- Grandi Navi Veloci
Ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 13h 5m
- Frequency
- 3 times a week
- Estimated price
- €80–120
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Santander to Pisa is 1435 km. It takes approximately 14h 4m to drive from Santander to Pisa.
Vueling Airlines, easyJet, Ulendo Airlink and three other airlines offer flights from Santander Airport Airport to Pisa International Airport Airport.
Book your Santander to Pisa bus tickets online with Omio and 12go.asia.
There are 4418+ hotels available in Pisa.















































