There are 10 ways to get from Santander to Perugia by plane, train, bus, car, or train (Renfe, TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane SDR - FLR
- Take the train from Firenze S.M.N. to Perugiatrain
8h 13m€108–263Bus via Milan
cheapest- Take the bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastiánbus
- Take the bus from San Sebastian Central Bus Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, Autostazione Lampugnano to Perugia Train Station Bus Stopbus
28h€73–120Bus, train via Antony
- Take the bus from Santander to San Sebastian / Donostiabus
- Take the train from Hendaye to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Perugiatrain Fr
22h 45m€304–637Bus
- Take the bus from Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Perugiabus 443 / ...
27h 10m€86–232Drive 1,653.4 km
- Drive from Santander to Perugiacar 1,653.4 km
16h 1m€260–375Fly to Fiumicino International Airport, train
- Fly from Santander Airport (SDR) to Fiumicino International Airport (FCO)plane SDR - FCO
- Take the train from Roma Termini to Folignotrain
8h 41m€99–271Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Santander Airport (SDR) to Bologna Guglielmo Marconi Airport (BLQ)plane SDR - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Perugiatrain
6h 30m€97–318Fly to Pisa International Airport, train
- Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane SDR - PSA
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Perugiatrain
10h 56m€162–281Train
- Take the train from Santander to Madrid Chamartíntrain Alv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgvtrain
- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Perugiatrain Fr
25h 42m€258–518Bus, train
- Take the bus from Santander to Padovabus
- Take the train from Padova to Bologna Centraletrain Fr
- Take the train from Bologna Centrale to Perugiatrain Fr
30h 7m€88–158
Santander to Perugia by bus, foot, and train
Questions & Answers
The cheapest way to get from Santander to Perugia is to bus via Milan which costs €70 - €120 and takes 28h.
The fastest way to get from Santander to Perugia is to fly and train which takes 6h 30m and costs €95 - €320.
No, there is no direct bus from Santander to Perugia. However, there are services departing from Santander and arriving at Perugia via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 27h 10m.
No, there is no direct train from Santander to Perugia. However, there are services departing from Santander and arriving at Perugia via Madrid Chamartín, Madrid-Puerta de Atocha-Almudena Grandes, Avignon Tgv, Lyon Part Dieu and Torino Porta Susa. The journey, including transfers, takes approximately 25h 42m.
The distance between Santander and Perugia is 1364 km. The road distance is 1653.4 km.
The best way to get from Santander to Perugia without a car is to bus and train via Antony which takes 22h 45m and costs €300 - €650.
It takes approximately 8h 13m to get from Santander to Perugia, including transfers.
Santander to Perugia bus services, operated by FlixBus, depart from Santander station.
Santander to Perugia train services, operated by Renfe Viajeros, depart from Santander station.
The best way to get from Santander to Perugia is to bus which takes 27h 10m and costs €85 - €240. Alternatively, you can train, which costs €250 - €550 and takes 25h 42m.
What companies run services between Santander, Spain and Perugia, Italy?
You can take a bus from Santander to Perugia via Bordeaux and Florence Villa Constanza Bus Station in around 27h 10m. Alternatively, you can take a train from Santander to Perugia via Madrid Chamartín, Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Avignon Tgv, Lyon Part Dieu, and Torino Porta Susa in around 25h 42m.
- Website
- iberia.com
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €90–220
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 7h 6m
- When
- Monday to Saturday
- Estimated price
- €90–350
Flights from Santander Airport to Fiumicino International Airport via Barcelona
- Ave. Duration
- 4h 20m
- When
- Tuesday and Thursday
- Estimated price
- €70–190
Flights from Santander Airport to Fiumicino International Airport via Madrid
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- €70–260
Flights from Santander Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 30m
- When
- Friday
- Estimated price
- €60–210
Flights from Santander Airport to Bologna Guglielmo Marconi Airport via Madrid
- Ave. Duration
- 5h
- When
- Monday to Friday
- Estimated price
- €80–290
- Website
- vueling.com
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €90–220
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 8h
- When
- Monday to Saturday
- Estimated price
- €90–350
Flights from Santander Airport to Florence Peretola Airport via Paris Orly
- Ave. Duration
- 7h 50m
- When
- Tuesday
- Estimated price
- €90–220
Flights from Santander Airport to Fiumicino International Airport via Barcelona
- Ave. Duration
- 4h 20m
- When
- Tuesday and Thursday
- Estimated price
- €70–190
Flights from Santander Airport to Fiumicino International Airport via Madrid
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €70–260
Flights from Santander Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 30m
- When
- Friday
- Estimated price
- €60–210
Flights from Santander Airport to Bologna Guglielmo Marconi Airport via Madrid
- Ave. Duration
- 5h
- When
- Monday to Friday
- Estimated price
- €80–290
- Website
- ryanair.com
Flights from Santander Airport to Fiumicino International Airport via Valencia
- Ave. Duration
- 7h 45m
- When
- Sunday
- Estimated price
- €85–190
Flights from Santander Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 5m
- When
- Sunday
- Estimated price
- €65–230
Flights from Santander Airport to Pisa International Airport via Valencia
- Ave. Duration
- 11h 25m
- When
- Sunday
- Estimated price
- €75–290
Flights from Santander Airport to Pisa International Airport via London Stansted
- Ave. Duration
- 11h 45m
- When
- Monday
- Estimated price
- €85–310
Flights from Santander Airport to Pisa International Airport via Madrid
- Ave. Duration
- 6h 5m
- When
- Monday and Friday
- Estimated price
- €75–290
Flights from Santander Airport to Pisa International Airport via Palma Mallorca
- Ave. Duration
- 7h
- When
- Monday
- Estimated price
- €75–290
- Website
- britishairways.com
Flights from Santander Airport to Florence Peretola Airport via Edinburgh
- Ave. Duration
- 7h 40m
- When
- Saturday
- Estimated price
- €130–800
- Website
- flyulendo.com
Flights from Santander Airport to Fiumicino International Airport via Menorca
- Ave. Duration
- 4h 5m
- When
- Tuesday and Saturday
- Estimated price
- €65–260
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 2h 11m
- Frequency
- Every 4 hours
- Estimated price
- €16
- Website
- https://www.trenitalia.com/en.html
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 56m
- Frequency
- Hourly
- Estimated price
- €12–25
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–24
- Website
- https://www.trenitalia.com/en.html
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- €17–60
- Website
- https://www.trenitalia.com/en.html
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 46m
- Frequency
- Hourly
- Estimated price
- €12
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- €11–22
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 54m
- Frequency
- 3 times a day
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- €10–16
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Perugia
- Ave. Duration
- 3h 11m
- Frequency
- Once daily
- Estimated price
- €16–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 31m
- Frequency
- 6 times a week
- Estimated price
- €16–35
- Schedules at
- trenitalia.com
Train from Torino Porta Susa to Perugia
- Ave. Duration
- 4h 40m
- Frequency
- 6 times a week
- Estimated price
- €65–110
- Schedules at
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 42m
- Frequency
- Once daily
- Estimated price
- €23–35
- Schedules at
- trenitalia.com
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €15–30
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Perugia
- Ave. Duration
- 2h 18m
- Frequency
- 6 times a week
- Estimated price
- €30–55
- Schedules at
- trenitalia.com
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Hendaye to Massy Tgv
- Ave. Duration
- 4h 41m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- https://www.sncf-connect.com/en-en
- 2nd Class
- €120–160
- 1st Class
- €150–200
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h 3m
- Frequency
- Every 4 hours
- Estimated price
- €45–140
- Website
- https://www.sncf-connect.com/en-en
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 10m
- Frequency
- Every 2 hours
- Estimated price
- €30–70
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €70–160
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €70–110
- Rail 1st Class
- €110–160
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €43–45
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 14m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.italotreno.it/en
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 7m
- Frequency
- Once a week
- Estimated price
- €13–26
- Website
- https://www.italotreno.it/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- €30–80
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgv
- Ave. Duration
- 7h 37m
- Frequency
- Once daily
- Estimated price
- €85–120
- Website
- https://www.renfe.com/es/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Santander to San Sebastian / Donostia
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- €17–24
- Website
- https://www.flixbus.co.uk
Bus from Santander to Bordeaux
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- €23–70
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €55–150
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Perugia
- Ave. Duration
- 1h 50m
- Frequency
- Every 4 hours
- Estimated price
- €8–15
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastián
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- €16–23
- Website
- https://www.alsa.com/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from San Sebastian Central Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 16h 30m
- Frequency
- 3 times a week
- Estimated price
- €45–70
- Website
- https://union-ivkoni.com/en
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Milano, Autostazione Lampugnano to Perugia Train Station Bus Stop
- Ave. Duration
- 6h 40m
- Frequency
- 6 times a week
- Estimated price
- €12–27
- Website
- https://www.itabus.it/en/home
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €60–75
- Schedules at
- tabitatour.ro
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More Questions & Answers
Santander to Perugia bus services, operated by FlixBus, arrive at Bordeaux station.
Santander to Perugia train services, operated by Renfe Viajeros, arrive at Madrid Chamartín station.
Yes, the driving distance between Santander to Perugia is 1653 km. It takes approximately 16h 1m to drive from Santander to Perugia.
Book your Santander to Perugia train tickets online with Omio.
Book your Santander to Perugia bus tickets online with Omio and FlixBus.
There are 1941+ hotels available in Perugia.

















































