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How to get fromSantander to Palermoby plane, car, car ferry, bus, train or ferry

Find Transport to Palermo

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There are 7 ways to get from Santander to Palermo by plane, car, car ferry, bus, train, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane plane SDR - PMO
    8h 43m
    €71–260
  2. Drive, car ferry

    1. Drive from Santander to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    33h 4m
    €260–429
  3. Bus, train

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the train from Bordeaux St Jean to Massy Tgvtrain train Tgv
    3. Take the train from Massy Tgv to Lyon Part Dieutrain train Tgv
    4. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    5. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    6. Take the train from Roma Termini to Palermo Centraletrain train Ic
    34h 1m
    €253–787
  4. Bus

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Palermobus bus
    42h 35m
    €113–367
  5. Train, ferry

    1. Take the train from Santander to Madrid Chamartíntrain train Alv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    3. Take the ferry from Port de Barcelona to Port of Civitavecchiaferry ferry
    4. Take the ferry from Port of Civitavecchia to Port of Palermoferry ferry
    42h 11m
    €173–421
  6. Bus, ferry

    1. Take the bus from Santander E.A. to Barcelona, Estación de Autobuses de Santsbus bus
    2. Take the ferry from Port de Barcelona to Port of Civitavecchiaferry ferry
    3. Take the ferry from Port of Civitavecchia to Port of Palermoferry ferry
    43h 5m
    €160–310
  7. Train, bus

    1. Take the train from Santander to Bilbaotrain train
    2. Take the train from Zazpikaleak/Casco Viejo-Bilbao to Amara-Donostiatrain train E1
    3. Take the bus from San Sebastian Central Bus Station to Milano, Autostazione Lampugnanobus bus
    4. Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus bus
    47h 35m
    €116–177

Santander to Palermo by bus, foot, and train

Calendar8Weekly Services
Duration34h 1mAverage Duration
Ticket€253Cheapest Price
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Questions & Answers

What companies run services between Santander, Spain and Palermo, Italy?

Iberia and Ryanair fly from Santander Airport (SDR) to Palermo Airport (PMO) once daily. Alternatively, you can take a bus from Santander to Palermo via Bordeaux and Florence Villa Constanza Bus Station in around 42h 35m.

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Bus operators
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