There are 7 ways to get from Santander to Palermo by plane, car, car ferry, bus, train, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane SDR - PMO
8h 43m€71–260Drive, car ferry
- Drive from Santander to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
33h 4m€260–429Bus, train
- Take the bus from Santander to Bordeauxbus
- Take the train from Bordeaux St Jean to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
34h 1m€253–787Bus
- Take the bus from Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Palermobus
42h 35m€113–367Train, ferry
- Take the train from Santander to Madrid Chamartíntrain Alv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port of Palermoferry
42h 11m€173–421Bus, ferry
- Take the bus from Santander E.A. to Barcelona, Estación de Autobuses de Santsbus
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port of Palermoferry
43h 5m€160–310Train, bus
- Take the train from Santander to Bilbaotrain
- Take the train from Zazpikaleak/Casco Viejo-Bilbao to Amara-Donostiatrain E1
- Take the bus from San Sebastian Central Bus Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus
47h 35m€116–177
Santander to Palermo by bus, foot, and train
Questions & Answers
The cheapest way to get from Santander to Palermo is to train and bus which costs €110 - €180 and takes 47h 35m.
The fastest way to get from Santander to Palermo is to fly which takes 8h 43m and costs €70 - €260.
No, there is no direct bus from Santander to Palermo. However, there are services departing from Santander and arriving at Palermo via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 42h 35m.
The distance between Santander and Palermo is 1567 km.
The best way to get from Santander to Palermo without a car is to bus and train which takes 34h 1m and costs €250 - €800.
It takes approximately 8h 43m to get from Santander to Palermo, including transfers.
Santander to Palermo bus services, operated by FlixBus, depart from Santander station.
The best way to get from Santander to Palermo is to fly which takes 8h 43m and costs €70 - €260. Alternatively, you can bus, which costs €110 - €370 and takes 42h 35m.
Santander to Palermo bus services, operated by FlixBus, arrive at Bordeaux station.
Book your Santander to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Palermo, Italy?
Iberia and Ryanair fly from Santander Airport (SDR) to Palermo Airport (PMO) once daily. Alternatively, you can take a bus from Santander to Palermo via Bordeaux and Florence Villa Constanza Bus Station in around 42h 35m.
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via London Stansted
- Ave. Duration
- 10h 20m
- When
- Thursday
- Estimated price
- €80–280
Flights from Santander Airport to Palermo Airport via Charleroi
- Ave. Duration
- 12h
- When
- Monday
- Estimated price
- €75–280
Flights from Santander Airport to Palermo Airport via Bologna
- Ave. Duration
- 14h 30m
- When
- Sunday
- Estimated price
- €65–260
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 9h 22m
- When
- Wednesday, Friday, and Saturday
- Estimated price
- €65–260
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 10h 10m
- When
- Monday and Thursday
- Estimated price
- €80–290
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 5m
- Frequency
- 5 times a day
- Estimated price
- €45–170
- Website
- https://www.sncf-connect.com/en-en
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h 3m
- Frequency
- Every 4 hours
- Estimated price
- €45–140
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 53m
- Frequency
- Once daily
- Estimated price
- €85–190
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €85–130
- Rail 1st Class
- €130–190
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €70–160
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €70–110
- Rail 1st Class
- €110–160
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €45–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €40–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- €30–80
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 4m
- Frequency
- Twice daily
- Estimated price
- €45–65
- Website
- https://www.renfe.com/es/en
Train from Santander to Bilbao
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a day
- Estimated price
- €9
- Website
- https://www.renfe.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €40–160
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- €40–110
- Website
- https://iryo.eu/en/home
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 4 hours
- Estimated price
- €30–70
- Website
- https://www.ouigo.com/es/en
- Phone
- +34 944 333 333
- digitala@euskotren.eus
- Website
- euskotren.eus
Train from Zazpikaleak/Casco Viejo-Bilbao to Amara-Donostia
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- €5–7
- Website
- https://www.euskotren.eus/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Santander to Bordeaux
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- €23–70
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €55–150
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h 15m
- Frequency
- Twice daily
- Estimated price
- €35–150
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
Bus from Milano, San Donato M3 to Palermo Via Tommaso Fazello
- Ave. Duration
- 21h
- Frequency
- Twice a week
- Estimated price
- €55–85
- Schedules at
- autoservizisalemi.it
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Barcelona, Estación de Autobuses de Sants
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- €50–130
- Website
- https://www.alsa.com/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from San Sebastian Central Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 16h 30m
- Frequency
- 3 times a week
- Estimated price
- €45–70
- Website
- https://union-ivkoni.com/en
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–140
- Website
- https://www.gnv.it/en
Ferry from Port of Civitavecchia to Port of Palermo
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €60–70
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €45–110
- Website
- https://www.grimaldi-lines.com/en/
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