There are 6 ways to get from Santander to Palermo by plane, car, car ferry, bus, train, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane SDR - PMO
5h 52m€89–182Drive, car ferry
- Drive from Santander to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
33h 4m€294–438Bus, train
- Take the bus from Santander to Bordeauxbus
- Take the train from Bordeaux St Jean to Massy Tgvtrain Tgv
- Take the train from Massy - Palaiseau to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
33h 57m€390–856Bus via Bordeaux
- Take the bus from Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Palermobus
42h 20m€160–361Bus, ferry
- Take the bus from Santander E.A. to Barcelona, Estación de Autobuses de Santsbus
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port of Palermoferry
43h 5m€185–332Bus
- Take the bus from Santander to Padovabus
- Take the bus from Padova to Parmabus
- Take the bus from Parma Via Villa Sant'Angelo to Palermo Via Tommaso Fazellobus
2d 3h€124–176
Santander to Palermo by bus
Questions & Answers
The cheapest way to get from Santander to Palermo is to fly which costs €85 - €190 and takes 5h 52m.
The fastest way to get from Santander to Palermo is to fly which takes 5h 52m and costs €85 - €190.
No, there is no direct bus from Santander to Palermo. However, there are services departing from Santander and arriving at Palermo via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 42h 20m.
The distance between Santander and Palermo is 1567 km.
The best way to get from Santander to Palermo without a car is to bus and train which takes 33h 57m and costs €390 - €900.
It takes approximately 5h 52m to get from Santander to Palermo, including transfers.
Santander to Palermo bus services, operated by FlixBus, depart from Santander station.
The best way to get from Santander to Palermo is to fly which takes 5h 52m and costs €85 - €190. Alternatively, you can bus via Bordeaux, which costs €160 - €370 and takes 42h 20m.
Santander to Palermo bus services, operated by FlixBus, arrive at Bordeaux station.
Book your Santander to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Palermo, Italy?
Ryanair, Vueling Airlines, and two other airlines fly from Santander Airport (SDR) to Palermo Airport (PMO) once daily. Alternatively, you can take a bus from Santander to Palermo via Bordeaux and Florence Villa Constanza Bus Station in around 42h 20m.
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via Bologna
- Ave. Duration
- 4h 50m
- When
- Thursday
- Estimated price
- €75–140
Flights from Santander Airport to Palermo Airport via Charleroi
- Ave. Duration
- 6h 5m
- When
- Saturday and Sunday
- Estimated price
- €75–140
Flights from Santander Airport to Palermo Airport via London Stansted
- Ave. Duration
- 7h 50m
- When
- Friday and Sunday
- Estimated price
- €75–140
Flights from Santander Airport to Palermo Airport via Valencia
- Ave. Duration
- 5h 30m
- When
- Friday
- Estimated price
- €75–140
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 6h 2m
- When
- Monday and Sunday
- Estimated price
- €100–180
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 9h 50m
- When
- Monday and Thursday
- Estimated price
- €90–320
- Website
- vueling.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 6h 2m
- When
- Monday and Sunday
- Estimated price
- €100–180
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 6m
- Frequency
- Every 4 hours
- Estimated price
- €100–170
- Website
- https://www.sncf-connect.com/en-en
Train from Massy - Palaiseau to Lyon Part Dieu
- Ave. Duration
- 2h 3m
- Frequency
- Every 4 hours
- Estimated price
- €90–140
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- €80–190
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Massy - Palaiseau to Lyon Part Dieu
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €65–160
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 2 22 55 00 10
- nomad-car@normandie.fr
- Website
- nomad.normandie.fr
Train from Massy - Palaiseau to Lyon Part Dieu
- Ave. Duration
- 2h 3m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–95
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €75–160
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €85–200
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Santander to Bordeaux
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €85–160
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €85–150
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
Bus from Parma Via Villa Sant'Angelo to Palermo Via Tommaso Fazello
- Ave. Duration
- 19h 15m
- Frequency
- Twice a week
- Estimated price
- €50–80
- Schedules at
- autoservizisalemi.it
- Phone
- +34 910 207 007
- Website
- alsa.com
Bus from Santander E.A. to Barcelona, Estación de Autobuses de Sants
- Ave. Duration
- 8h 45m
- Frequency
- Twice daily
- Estimated price
- €55–120
- Website
- https://www.alsa.com/en/
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €60–75
- Schedules at
- tabitatour.ro
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Padova to Parma
- Ave. Duration
- 5h
- Frequency
- 3 times a day
- Estimated price
- €12–23
- Website
- https://www.itabus.it/en/home
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–150
- Website
- https://www.gnv.it/en
Ferry from Port of Civitavecchia to Port of Palermo
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €55–85
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €70–130
- Website
- https://www.grimaldi-lines.com/en/
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