There are 6 ways to get from Santander to Palermo by plane, car, car ferry, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane SDR - PMO
8h 17m€95–160Drive, car ferry
- Drive from Santander to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
33h 4m€261–423Train, bus
- Take the train from Santander to Basurto Hospitaltrain
- Take the bus from Bilbao to Toulousebus
- Take the train from Toulouse Matabiau to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
37h 9m€206–534Bus
- Take the bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastiánbus
- Take the bus from San Sebastian Central Bus Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, Autostazione Lampugnano to Palermobus
43h 15m€96–191Bus, ferry
- Take the bus from Santander E.A. to Barcelona, Estación de Autobuses de Santsbus
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port of Palermoferry
43h 5m€145–360Bus, train
- Take the bus from Santander to Padovabus
- Take the train from Padova to Bologna Centraletrain
- Take the bus from Bologna Centrale to Trapani Imbarco Aliscafo Liberty Linesbus
- Take the bus from Trapani Imbarco Aliscafo Liberty Lines to Palermo-Via Libertàbus
2d 1h€135–195
Santander to Palermo by train, foot, and bus
Questions & Answers
The cheapest way to get from Santander to Palermo is to fly which costs €95 - €160 and takes 8h 17m.
The fastest way to get from Santander to Palermo is to fly which takes 8h 17m and costs €95 - €160.
No, there is no direct bus from Santander to Palermo. However, there are services departing from Santander E.A. and arriving at Palermo via San Sebastian Central Bus Station and Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 43h 15m.
The distance between Santander and Palermo is 1567 km.
The best way to get from Santander to Palermo without a car is to train and bus which takes 37h 9m and costs €200 - €550.
It takes approximately 8h 17m to get from Santander to Palermo, including transfers.
Santander to Palermo bus services, operated by ALSA, depart from Santander E.A. station.
The best way to get from Santander to Palermo is to fly which takes 8h 17m and costs €95 - €160. Alternatively, you can bus, which costs €95 - €200 and takes 43h 15m.
Santander to Palermo bus services, operated by ALSA, arrive at Estación de Autobuses Donostia-San Sebastián station.
Book your Santander to Palermo bus tickets online with Omio.
What companies run services between Santander, Spain and Palermo, Italy?
Ryanair and Iberia fly from Santander Airport (SDR) to Palermo Airport (PMO) once daily. Alternatively, you can take a bus from Santander E.A. to Palermo via San Sebastian Central Bus Station and Milano, Autostazione Lampugnano in around 43h 15m.
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via London Stansted
- Ave. Duration
- 9h 45m
- When
- Thursday and Saturday
- Estimated price
- €75–260
Flights from Santander Airport to Palermo Airport via Charleroi
- Ave. Duration
- 12h
- When
- Monday
- Estimated price
- €70–260
Flights from Santander Airport to Palermo Airport via Bologna
- Ave. Duration
- 14h 30m
- When
- Sunday
- Estimated price
- €65–240
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 9h 10m
- When
- Saturday
- Estimated price
- €60–240
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 10h 10m
- When
- Monday and Thursday
- Estimated price
- €75–300
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Basurto Hospital
- Ave. Duration
- 3h 4m
- Frequency
- 3 times a day
- Estimated price
- €8–15
- Website
- https://www.renfe.com/es/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Toulouse Matabiau to Lyon Part Dieu
- Ave. Duration
- 4h 9m
- Frequency
- 3 times a day
- Estimated price
- €35–110
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €50–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €45–100
- Website
- https://www.italotreno.it/en
Train from Padova to Bologna Centrale
- Ave. Duration
- 1h 2m
- Frequency
- Every 2 hours
- Estimated price
- €13–26
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €27–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Bilbao to Toulouse
- Ave. Duration
- 5h 55m
- Frequency
- 5 times a week
- Estimated price
- €35–50
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €35–90
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastián
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- €16–35
- Website
- https://www.alsa.com/en/
Bus from Santander E.A. to Barcelona, Estación de Autobuses de Sants
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- €50–130
- Website
- https://www.alsa.com/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from San Sebastian Central Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 16h 30m
- Frequency
- 3 times a week
- Estimated price
- €45–70
- Website
- https://union-ivkoni.com/en
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
Bus from Bologna Centrale to Trapani Imbarco Aliscafo Liberty Lines
- Ave. Duration
- 19h
- Frequency
- Twice a week
- Estimated price
- €50–80
- Schedules at
- autoservizisalemi.it
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €60–75
- Schedules at
- tabitatour.ro
- Phone
- 06 164 160, +39091342525
- info@segesta.it
- Website
- segesta.it
Bus from Trapani Imbarco Aliscafo Liberty Lines to Palermo-Via Libertà
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €11–16
- Schedules at
- segesta.it
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €65–140
- Website
- https://www.gnv.it/en
Ferry from Port of Civitavecchia to Port of Palermo
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €50–130
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €40–100
- Website
- https://www.grimaldi-lines.com/en/
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