There are 7 ways to get from Santander to Palermo by plane, car, car ferry, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane SDR - PMO
6h 32m€60–246Drive, car ferry
- Drive from Santander to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
33h 4m€260–429Train, bus
- Take the train from Santander to Madrid Chamartíntrain Alv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Aix En Provence Tgvtrain
- Take the bus from Gare Aix TGV RD9 to Montgenèvre - Gare Routièrebus 50
- Take the train from Bardonecchia to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
38h 45mBus via Bordeaux
- Take the bus from Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Palermobus
42h 35m€113–367Train, bus, car ferry
- Take the train from Santander to Madrid Chamartíntrain Alv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the car ferry from Port of Genoa to Port of Palermocarferry
42h 19m€206–398Bus, ferry
- Take the bus from Santander E.A. to Barcelona, Estación de Autobuses de Santsbus
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port of Palermoferry
43h 5m€160–310Bus
- Take the bus from Santander E.A. to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Vitoria-Gasteizbus
- Take the bus from Vitoria Gasteiz Central Bus Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus
2d 2h€129–209
Santander to Palermo by bus
Questions & Answers
The cheapest way to get from Santander to Palermo is to fly which costs €60 - €250 and takes 6h 32m.
The fastest way to get from Santander to Palermo is to fly which takes 6h 32m and costs €60 - €250.
No, there is no direct bus from Santander to Palermo. However, there are services departing from Santander and arriving at Palermo via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 42h 35m.
The distance between Santander and Palermo is 1567 km.
The best way to get from Santander to Palermo without a car is to bus via Bordeaux which takes 42h 35m and costs €110 - €370.
It takes approximately 6h 32m to get from Santander to Palermo, including transfers.
Santander to Palermo bus services, operated by FlixBus, depart from Santander station.
The best way to get from Santander to Palermo is to fly which takes 6h 32m and costs €60 - €250. Alternatively, you can bus via Bordeaux, which costs €110 - €370 and takes 42h 35m.
Santander to Palermo bus services, operated by FlixBus, arrive at Bordeaux station.
Book your Santander to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Palermo, Italy?
Vueling Airlines, Iberia, and Ryanair fly from Santander Airport (SDR) to Palermo Airport (PMO) once daily. Alternatively, you can take a bus from Santander to Palermo via Bordeaux and Florence Villa Constanza Bus Station in around 42h 35m.
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via London Stansted
- Ave. Duration
- 10h 20m
- When
- Thursday
- Estimated price
- €85–290
Flights from Santander Airport to Palermo Airport via Charleroi
- Ave. Duration
- 12h
- When
- Monday
- Estimated price
- €80–280
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 7h 40m
- When
- Wednesday and Friday
- Estimated price
- €70–260
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 30m
- When
- Thursday
- Estimated price
- €55–240
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 10h 10m
- When
- Monday and Thursday
- Estimated price
- €80–290
- Website
- vueling.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 30m
- When
- Thursday
- Estimated price
- €55–240
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- €30–80
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Aix En Provence Tgv
- Ave. Duration
- 7h 59m
- Frequency
- Once daily
- Estimated price
- €90–120
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bardonecchia to Roma Termini
- Ave. Duration
- 5h 55m
- Frequency
- 3 times a week
- Estimated price
- €75–150
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €40–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 4 13943050
- Website
- zou.maregionsud.fr
Bus from Gare Aix TGV RD9 to Montgenèvre - Gare Routière
- Ave. Duration
- 4h 5m
- Frequency
- 4 times a week
- Website
- https://zou.maregionsud.fr/en/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Santander to Bordeaux
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- €23–70
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €55–150
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h 15m
- Frequency
- Twice daily
- Estimated price
- €35–150
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
Bus from Milano, San Donato M3 to Palermo Via Tommaso Fazello
- Ave. Duration
- 21h
- Frequency
- Twice a week
- Estimated price
- €55–85
- Schedules at
- autoservizisalemi.it
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 5h 35m
- Frequency
- 3 times a day
- Estimated price
- €20–50
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Barcelona, Estación de Autobuses de Sants
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- €50–130
- Website
- https://www.alsa.com/en/
Bus from Santander E.A. to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- https://www.alsa.com/en/
Bus from Bilbao Intermodal to Vitoria-Gasteiz
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €5–8
- Website
- https://www.alsa.com/en/
- Phone
- +34 94 476 50 07
- Website
- autobuseslaunion.com
Bus from Bilbao Intermodal to Vitoria-Gasteiz
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.autobuseslaunion.com/en
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Vitoria Gasteiz Central Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 23h 30m
- Frequency
- Twice a week
- Estimated price
- €60–95
- Website
- https://union-ivkoni.com/en
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–140
- Website
- https://www.gnv.it/en
Ferry from Port of Civitavecchia to Port of Palermo
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €60–70
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €45–110
- Website
- https://www.grimaldi-lines.com/en/
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in Spain: A guide to Renfe
Read the travel guide
More Questions & Answers
There are 5713+ hotels available in Palermo.















































