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How to get fromSantander to Lyonby plane, train (Renfe, Ouigo), bus, car, or train

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There are 6 ways to get from Santander to Lyon by plane, train (Renfe, Ouigo), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Santander Airport (SDR) to Lyon–Saint Exupéry Airport (LYS)plane plane SDR - LYS
    5h 6m
    €104–321

  2. Bus via Bilbao

    cheapest
    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus ALSA - Stder-Irun / ...
    2. Take the bus from Bilbao to Lyonbus bus FlixBus N1149 / ...
    15h 30m
    €74–123

  3. Train

    1. Take the train from Santander to Madrid Chamartíntrain train Alv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    3. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    13h 44m
    €197–377

  4. Bus

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus ALSA - Stder-Irun / ...
    2. Take the bus from Bilbao Intermodal to Lyon - Gerland Bus Stationbus bus BlaBlaCar Bus
    15h 25m
    €84–153

  5. Drive 954.9 km

    1. Drive from Santander to Lyoncar car 954.9 km
    9h 29m
    €151–218

  6. Bus, train

    1. Take the bus from Santander to Bayonne - Quai de Lesseps Bus Stopbus bus
    2. Take the train from Bayonne to Toulouse Matabiautrain train
    3. Take the train from Toulouse Matabiau to Lyon Part Dieutrain train Tgv
    14h 31m
    €182–328

Santander to Lyon by train

Calendar14Weekly Trains
Duration13h 44mAverage Duration
Ticket€197Cheapest Price
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Questions & Answers

Map of how to get from Santander to Lyon.ExpandLaunch map view
  • Distance: 770.7 km
  • Duration: 5h 6m

What companies run services between Santander, Spain and Lyon, France?

Iberia, Vueling Airlines, and three other airlines fly from Santander Airport (SDR) to Lyon–Saint Exupéry Airport (LYS) 3 times a day. Alternatively, you can take a train from Santander to Lyon Part Dieu via Madrid Chamartín, Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, and Barcelona-Sants in around 13h 44m.

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