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How to get fromSantander to Lyonby plane, train (Renfe, Ouigo, TGV), bus, car, or train (Renfe, TGV)

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There are 6 ways to get from Santander to Lyon by plane, train (Renfe, Ouigo, TGV), bus, car, or train (Renfe, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Santander Airport (SDR) to Lyon–Saint Exupéry Airport (LYS)plane plane SDR - LYS
    5h 51m
    €111–330

  2. Bus

    cheapest
    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus ALSA - Stder-Irun / ...
    2. Take the bus from Bilbao Intermodal to Lyon - Gerland Bus Stationbus bus BlaBlaCar Bus
    15h 25m
    €64–108

  3. Train via Madrid

    1. Take the train from Santander to Madrid Chamartíntrain train Alv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    3. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    13h 29m
    €182–431

  4. Drive  954.9 km

    1. Drive from Santander to Lyoncar car 954.9 km
    9h 29m
    €155–224

  5. Bus via Bilbao

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus ALSA - Stder-Irun / ...
    2. Take the bus from Bilbao to Lyonbus bus FlixBus N1149 / ...
    15h 30m
    €79–123

  6. Train

    1. Take the train from Santander to Bilbaotrain train
    2. Take the train from Zazpikaleak/Casco Viejo-Bilbao to Amara-Donostiatrain train E1
    3. Take the train from Hendaye to Toulouse Matabiautrain train
    4. Take the train from Toulouse Matabiau to Lyon Part Dieutrain train Tgv
    17h 23m
    €176–305

Santander to Lyon by train

Calendar18Weekly Trains
Duration13h 29mAverage Duration
Ticket€182Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santander to Lyon.ExpandLaunch map view
  • Distance: 770.7 km
  • Duration: 5h 51m

What companies run services between Santander, Spain and Lyon, France?

Iberia, Vueling Airlines, and three other airlines fly from Santander Airport (SDR) to Lyon–Saint Exupéry Airport (LYS) 4 times a day. Alternatively, you can take a train from Santander to Lyon Part Dieu via Madrid Chamartín, Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, and Barcelona-Sants in around 13h 29m.

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