There are 9 ways to get from Santa Rosa to Mayo Clinic by plane, bus, bus (Amtrak, Greyhound), train, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Sonoma County Airport to Minneapolis–Saint Paul International Airport, bus
best- Fly from Sonoma County Airport (STS) to Minneapolis–Saint Paul International Airport (MSP)plane STS - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
10h 30m$238–857Train, bus to San Francisco International Airport, fly to Rochester
cheapest- Take the train from SMART Santa Rosa Downtown to SMART Larkspurtrain
- Take the bus from Larkspur - pickup to San Francisco Airportbus
- Fly from San Francisco International Airport (SFO) to Rochester (RST)plane SFO - RST
10h 28m$144–569Bus
- Take the bus from Santa Rosa Amtrak Bus Stop to Vallejobus
- Take the bus from Vallejo Transit Center to Sparks Transit Centerbus
- Take the bus from Sparks Transit Center to Denver Union Stationbus
- Take the bus from Denver Union Station to Des Moinesbus
- Take the bus from Des Moines to St. Paulbus
- Take the bus from St. Paul to Rochester, MNbus
2d 3h$387–723Bus, train via Portland
- Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus
- Take the train from Martinez to Portlandtrain
- Take the train from Portland to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochester, MNbus
2d 13h$747–1,699Drive 1,935.1 mi
- Drive from Santa Rosa to Mayo Cliniccar 1,935.1 mi
31h 42m$354–511Train, bus to San Francisco International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from SMART Santa Rosa Downtown to SMART Larkspurtrain
- Take the bus from Larkspur - pickup to San Francisco Airportbus
- Fly from San Francisco International Airport (SFO) to Minneapolis–Saint Paul International Airport (MSP)plane SFO - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
10h 6m$225–691Train, BART to Norman Y. Mineta San José International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from SMART Santa Rosa Downtown to SMART San Rafaeltrain
- Take the subway from El Cerrito Del Norte to Milpitassubway
- Fly from Norman Y. Mineta San José International Airport (SJC) to Minneapolis–Saint Paul International Airport (MSP)plane SJC - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
11h 48m$308–1,180Train, train to Sacramento International Airport, fly to Rochester
- Take the train from SMART Santa Rosa Downtown to SMART San Rafaeltrain
- Take the train from Richmond to Sacramentotrain
- Fly from Sacramento International Airport (SMF) to Rochester (RST)plane SMF - RST
14h 40m$212–911Bus, train
- Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus
- Take the train from Martinez to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
2d 16h$794–1,659
Santa Rosa to Mayo Clinic by bus, train, and foot
Questions & Answers
The cheapest way to get from Santa Rosa to Mayo Clinic is to train and bus and fly which costs $140 - $600 and takes 10h 28m.
The fastest way to get from Santa Rosa to Mayo Clinic is to train and bus and fly which takes 10h 6m and costs $220 - $700.
No, there is no direct bus from Santa Rosa to Mayo Clinic. However, there are services departing from Santa Rosa Amtrak Bus Stop and arriving at Rochester, MN via Vallejo Transit Center, Sparks Transit Center, Denver Union Station, Des Moines and St. Paul. The journey, including transfers, takes approximately 2 days 3h.
The distance between Santa Rosa and Mayo Clinic is 1678 miles. The road distance is 1946.3 miles.
The best way to get from Santa Rosa to Mayo Clinic without a car is to bus which takes 2 days 3h and costs $380 - $750.
It takes approximately 10h 30m to get from Santa Rosa to Mayo Clinic, including transfers.
Santa Rosa to Mayo Clinic bus services, operated by Amtrak, depart from Santa Rosa Amtrak Bus Stop station.
Santa Rosa to Mayo Clinic bus services, operated by Amtrak, arrive at Vallejo station.
Yes, the driving distance between Santa Rosa to Mayo Clinic is 1946 miles. It takes approximately 31h 42m to drive from Santa Rosa to Mayo Clinic.
There are 71+ hotels available in Mayo Clinic.
What companies run services between Santa Rosa, CA, USA and Mayo Clinic, MN, USA?
You can take a bus from Santa Rosa Amtrak Bus Stop to Mayo Clinic via Vallejo Transit Center, Sparks Transit Center, Denver Union Station, Des Moines, St. Paul, and Rochester in around 2d 3h.
- Website
- delta.com
Flights from Sonoma County Airport to Minneapolis–Saint Paul International Airport via Salt Lake City
- Ave. Duration
- 7h 4m
- When
- Every day
- Estimated price
- $170–750
Flights from Sonoma County Airport to Minneapolis–Saint Paul International Airport via Portland
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $200–850
Flights from San Francisco International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- $110–490
Flights from San Francisco International Airport to Rochester via Salt Lake City, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 10h 42m
- When
- Every day
- Estimated price
- $110–490
Flights from San Francisco International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $140–600
Flights from San Francisco International Airport to Minneapolis–Saint Paul International Airport via Salt Lake City
- Ave. Duration
- 5h 32m
- When
- Monday to Friday
- Estimated price
- $140–600
Flights from Norman Y. Mineta San José International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Norman Y. Mineta San José International Airport to Minneapolis–Saint Paul International Airport via Salt Lake City
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Sacramento International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 7h 28m
- When
- Every day
- Estimated price
- $180–800
Flights from Sacramento International Airport to Rochester via Salt Lake City, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 10h 43m
- When
- Every day
- Estimated price
- $180–800
- Website
- united.com
Flights from San Francisco International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $140–600
Flights from San Francisco International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $140–600
Flights from San Francisco International Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $140–650
Flights from Norman Y. Mineta San José International Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $250–1,100
Flights from Sacramento International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 8h 30m
- When
- Every day
- Estimated price
- $220–900
- Website
- aa.com
Flights from Sonoma County Airport to Minneapolis–Saint Paul International Airport via Phoenix
- Ave. Duration
- 8h 49m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–850
Flights from San Francisco International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 8h 6m
- When
- Every day
- Estimated price
- $140–600
Flights from Sacramento International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 7h 41m
- When
- Every day
- Estimated price
- $220–900
- Website
- suncountry.com
Flights from Sonoma County Airport to Minneapolis–Saint Paul International Airport via Los Angeles
- Ave. Duration
- 6h 30m
- When
- Monday, Friday, and Sunday
- Estimated price
- $200–850
Flights from San Francisco International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $140–600
- Website
- southwest.com
Flights from Norman Y. Mineta San José International Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 5h 48m
- When
- Tuesday to Friday
- Estimated price
- $250–1,100
- Website
- alaskaair.com
Flights from Sonoma County Airport to Minneapolis–Saint Paul International Airport via Portland
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $200–850
Flights from Sonoma County Airport to Minneapolis–Saint Paul International Airport via Phoenix
- Ave. Duration
- 8h 49m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–850
- Website
- flyfrontier.com
Flights from Sonoma County Airport to Minneapolis–Saint Paul International Airport via Phoenix
- Ave. Duration
- 6h 22m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $210–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Martinez to Portland
- Ave. Duration
- 17h 14m
- Frequency
- Once daily
- Estimated price
- $200–430
- Website
- https://www.amtrak.com/home.html
Train from Portland to St. Paul-Minneapolis
- Ave. Duration
- 37h 48m
- Frequency
- Once daily
- Estimated price
- $500–1,200
- Website
- https://www.amtrak.com/home.html
Train from Richmond to Sacramento
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $22–50
- Website
- https://www.amtrak.com/home.html
Train from Martinez to Chicago Union Station
- Ave. Duration
- 2d 3h
- Frequency
- Once daily
- Estimated price
- $700–1,500
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 707-794-3330
- Website
- sonomamarintrain.org
Train from SMART Santa Rosa Downtown to SMART Larkspur
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- $1–7
- Website
- https://sonomamarintrain.org/
- Website
- https://sonomamarintrain.org/
Train from SMART Santa Rosa Downtown to SMART San Rafael
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $1–7
- Website
- https://sonomamarintrain.org/
- Website
- https://sonomamarintrain.org/
- Phone
- +1-510-464-6000
- Website
- bart.gov
Subway from El Cerrito Del Norte to Milpitas
- Ave. Duration
- 1h 13m
- Frequency
- Every 30 minutes
- Estimated price
- $7–11
- Website
- https://www.bart.gov
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Santa Rosa Amtrak Bus Stop to Vallejo
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $15–23
- Website
- https://www.amtrak.com/home.html
Bus from Santa Rosa Amtrak Bus Stop to Martinez
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $19–29
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Vallejo Transit Center to Sparks Transit Center
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Sparks Transit Center to Denver Union Station
- Ave. Duration
- 20h 55m
- Frequency
- Once daily
- Estimated price
- $150–310
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Des Moines
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $100–200
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $65–90
- Book at
- https://www.jeffersonlines.com
- Adult
- $65–90
Bus from St. Paul to Rochester, MN
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
- Phone
- +1 415-461-4222
- Website
- marinairporter.com
Bus from Larkspur - pickup to San Francisco Airport
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $32
- Website
- https://marinairporter.com/
- Adult One-way
- $32
- Phone
- +1 (866) 912 - 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- coachusa.com
- Adult
- $25–55
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