Rome2Rio

How to get fromSanta Rosa to Mayo Clinicby bus, plane, bus (Amtrak, Greyhound), train, car or subway

Find Transport to Mayo Clinic

See all options

There are 10 ways to get from Santa Rosa to Mayo Clinic by bus, plane, bus (Amtrak, Greyhound), train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to San Francisco International Airport, fly to Rochester

    best
    1. Take the bus from Santa Rosa to San Francisco Airportbus bus
    2. Fly from San Francisco International Airport (SFO) to Rochester (RST)plane plane SFO - RST
    10h 12m
    $132–601
  2. Bus

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Vallejobus bus
    2. Take the bus from Vallejo Transit Center to Sparks Transit Centerbus bus
    3. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Des Moinesbus bus
    5. Take the bus from Des Moines to St. Paulbus bus
    6. Take the bus from St. Paul to Rochesterbus bus
    2d 3h
  3. Bus, train via Portland

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Portlandtrain train
    3. Take the train from Portland to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    2d 13h
  4. Drive 1,935.1 mi

    1. Drive from Santa Rosa to Mayo Cliniccar car 1,935.1 mi
    31h 42m
    $354–511
  5. Bus to San Francisco International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Santa Rosa to San Francisco Airportbus bus
    2. Fly from San Francisco International Airport (SFO) to Minneapolis–Saint Paul International Airport (MSP)plane plane SFO - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 43m
    $192–834
  6. Fly Sonoma County Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Sonoma County Airport (STS) to Minneapolis–Saint Paul International Airport (MSP)plane plane STS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    10h 10m
    $223–925
  7. Bus, BART to Norman Y. Mineta San José International Airport, fly to Minneapolis–Saint Paul International Airport

    1. Take the bus from Santa Rosa Transit Mall to Battery St & Sacramento Stbus bus
    2. Take the subway from Embarcadero to Milpitassubway subway
    3. Fly from Norman Y. Mineta San José International Airport (SJC) to Minneapolis–Saint Paul International Airport (MSP)plane plane SJC - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    11h 10m
    $251–1,050
  8. Bus, train to Sacramento International Airport, fly to Rochester

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Sacramentotrain train
    3. Fly from Sacramento International Airport (SMF) to Rochester (RST)plane plane SMF - RST
    14h 21m
  9. Bus, train to Sacramento International Airport, fly to Minneapolis–Saint Paul International Airport

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Sacramentotrain train
    3. Fly from Sacramento International Airport (SMF) to Minneapolis–Saint Paul International Airport (MSP)plane plane SMF - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    12h 2m
  10. Bus, train

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    2d 16h

San Francisco International Airport (SFO) to Rochester (RST) flights

Calendar42Weekly Planes
Duration7h 36mAverage Duration
Ticket$112Cheapest Price
See schedules

Questions & Answers

What companies run services between Santa Rosa, CA, USA and Mayo Clinic, MN, USA?

You can take a bus from Santa Rosa Amtrak Bus Stop to Mayo Clinic via Vallejo Transit Center, Sparks Transit Center, Denver Union Station, Des Moines, St. Paul, and Rochester in around 2d 3h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound