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How to get fromSanta Rosa to Mayo Clinicby train, bus, plane, bus (Greyhound), car, or subway

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There are 9 ways to get from Santa Rosa to Mayo Clinic by train, bus, plane, bus (Greyhound), car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus to San Francisco International Airport, fly to Rochester

    best
    1. Take the train from SMART Santa Rosa Downtown to SMART Larkspurtrain train
    2. Take the bus from Larkspur - pickup to San Francisco Airportbus bus
    3. Fly from San Francisco International Airport (SFO) to Rochester (RST)plane plane SFO - RST
    10h 28m
    $144–569

  2. Bus

    1. Take the bus from Santa Rosa Transit Mall to 1st St & Mission Stbus bus 172
    2. Take the bus from San Francisco Bus Station to Sparks Transit Centerbus bus
    3. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Des Moinesbus bus
    5. Take the bus from Des Moines to St. Paulbus bus
    6. Take the bus from St. Paul to Rochester, MNbus bus
    2d 5h
    $398–724

  3. Bus, train via Portland

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Portlandtrain train
    3. Take the train from Portland to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochester, MNbus bus
    2d 13h
    $878–1,728

  4. Drive 1,935.1 mi

    1. Drive from Santa Rosa to Mayo Cliniccar car 1,935.1 mi
    31h 42m
    $354–511

  5. Fly Sonoma County Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Sonoma County Airport (STS) to Minneapolis–Saint Paul International Airport (MSP)plane plane STS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 28m
    $168–557

  6. Train, bus to San Francisco International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from SMART Santa Rosa Downtown to SMART Larkspurtrain train
    2. Take the bus from Larkspur - pickup to San Francisco Airportbus bus
    3. Fly from San Francisco International Airport (SFO) to Minneapolis–Saint Paul International Airport (MSP)plane plane SFO - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    10h 8m
    $205–411

  7. Train, BART to Norman Y. Mineta San José International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from SMART Santa Rosa Downtown to SMART San Rafaeltrain train
    2. Take the subway from El Cerrito Del Norte to Milpitassubway subway
    3. Fly from Norman Y. Mineta San José International Airport (SJC) to Minneapolis–Saint Paul International Airport (MSP)plane plane SJC - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    11h 43m
    $509–731

  8. Train, train to Sacramento International Airport, fly to Rochester

    1. Take the train from SMART Santa Rosa Downtown to SMART San Rafaeltrain train
    2. Take the train from Richmond to Sacramentotrain train
    3. Fly from Sacramento International Airport (SMF) to Rochester (RST)plane plane SMF - RST
    14h 37m
    $186–761

  9. Bus, train

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    2d 16h
    $845–1,758

Santa Rosa to Mayo Clinic by bus, train, and foot

Calendar7Weekly Services
Duration2d 13hAverage Duration
Ticket$878Cheapest Price
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Questions & Answers

Map of how to get from Santa Rosa to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,691.9 mi
  • Duration: 10h 28m

What companies run services between Santa Rosa, CA, USA and Mayo Clinic, MN, USA?

You can take a bus from Santa Rosa Transit Mall to Mayo Clinic via 1st St & Mission St, San Francisco Bus Station, Sparks Transit Center, Denver Union Station, Des Moines, St. Paul, and Rochester in around 2d 5h.

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