Rome2Rio

How to get fromSanta Rosa to Greenvilleby bus, plane, bus (Greyhound), train or car

Find Transport to Greenville

See all options

There are 9 ways to get from Santa Rosa to Greenville by bus, plane, bus (Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to San Francisco International Airport, fly

    best
    1. Take the bus from Santa Rosa to San Francisco Airportbus bus
    2. Fly from San Francisco International Airport (SFO) to Greenville–Spartanburg International Airport (GSP)plane plane SFO - GSP
    9h 48m
    $221–851

  2. Bus

    1. Take the bus from Santa Rosa to Phoenix Bus Stationbus bus
    2. Take the bus from Phoenix Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    2d 19h
    $439–835

  3. Bus, train

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    3d 3h
    $665–1,719

  4. Drive 2,643.1 mi

    1. Drive from Santa Rosa to Greenvillecar car 2,643.1 mi
    42h 32m
    $483–697

  5. Fly from Sonoma County Airport

    1. Fly from Sonoma County Airport (STS) to Greenville–Spartanburg International Airport (GSP)plane plane STS - GSP
    8h 28m
    $242–992

  6. Bus to Oakland International Airport, fly

    1. Take the bus from Santa Rosa to Oakland International Airportbus bus
    2. Fly from Oakland International Airport (OAK) to Greenville–Spartanburg International Airport (GSP)plane plane OAK - GSP
    11h 48m
    $261–1,000

  7. Bus, train to Sacramento International Airport, fly

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Sacramentotrain train
    3. Fly from Sacramento International Airport (SMF) to Greenville–Spartanburg International Airport (GSP)plane plane SMF - GSP
    12h 13m
    $280–1,101

  8. Bus, train via Maricopa

    1. Take the bus from Santa Rosa to Phoenix Bus Stationbus bus
    2. Take the bus from Sky Harbor International Airport to Maricopa Amtrakbus bus
    3. Take the train from Maricopa Amtrak to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain train
    5. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    3d 12h
    $672–1,486

  9. Bus, train via Cary

    1. Take the bus from Petaluma to Martinezbus bus
    2. Take the train from Martinez to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carytrain train
    4. Take the train from Cary to Charlotte Amtrak Stationtrain train
    5. Take the bus from Charlotte, NC to Greenville, SCbus bus
    3d 15h
    $861–2,059

San Francisco International Airport (SFO) to Greenville–Spartanburg International Airport (GSP) flights

Calendar44Weekly Planes
Duration7h 22mAverage Duration
Ticket$171Cheapest Price
See schedules

Questions & Answers

What companies run services between Santa Rosa, CA, USA and Greenville, SC, USA?

You can take a bus from Santa Rosa to Greenville via Phoenix Bus Station, Dallas Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - North Loop/Morosgo Dr, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 2d 19h. Alternatively, American Airlines flies from Sonoma County Airport (STS) to Greenville–Spartanburg International Airport (GSP) once daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Santa Rosa

Trips to Greenville

Popular routes