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How to get fromSanta Rosa to Des Moinesby plane, bus (Greyhound), bus, train, or car

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There are 6 ways to get from Santa Rosa to Des Moines by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Sonoma County Airport

    best
    1. Fly from Sonoma County Airport (STS) to Des Moines (DSM)plane plane STS - DSM
    7h 26m
    $173–676

  2. Bus

    1. Take the bus from Santa Rosa Transit Mall to 1st St & Mission Stbus bus 172
    2. Take the bus from San Francisco Bus Station to Sparks Transit Centerbus bus
    3. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Des Moinesbus bus
    44h 47m
    $305–594

  3. Bus, train

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Denvertrain train
    3. Take the bus from Denver to Omaha, NEbus bus
    4. Take the bus from Omaha, NE to Des Moinesbus bus
    2d 1h
    $630–1,148

  4. Drive 1,798 mi

    1. Drive from Santa Rosa to Des Moinescar car 1,798 mi
    27h 39m
    $329–474

  5. Train, bus to San Francisco International Airport, fly

    1. Take the train from SMART Santa Rosa Downtown to SMART Larkspurtrain train
    2. Take the bus from Larkspur - pickup to San Francisco Airportbus bus
    3. Fly from San Francisco International Airport (SFO) to Des Moines (DSM)plane plane SFO - DSM
    9h 13m
    $240–710

  6. Train, bus to Oakland International Airport, fly

    1. Take the train from SMART Santa Rosa Downtown to SMART San Rafaeltrain train
    2. Take the bus from San Rafael to Oakland International Airportbus bus
    3. Fly from Oakland International Airport (OAK) to Des Moines (DSM)plane plane OAK - DSM
    9h 23m
    $263–1,032

Santa Rosa to Des Moines by bus

Calendar7Weekly Buses
Duration44h 47mAverage Duration
Ticket$305Cheapest Price
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Questions & Answers

Map of how to get from Santa Rosa to Des Moines.ExpandLaunch map view
  • Distance: 1,565.1 mi
  • Duration: 7h 26m

What companies run services between Santa Rosa, CA, USA and Des Moines, IA, USA?

Southwest Airlines, Alaska Airlines, Inc., and American Airlines fly from Sonoma County Airport (STS) to Des Moines (DSM) 4 times a day. Alternatively, you can take a bus from Santa Rosa Transit Mall to Des Moines via 1st St & Mission St, San Francisco Bus Station, Sparks Transit Center, and Denver Union Station in around 44h 47m.

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