There are 7 ways to get from Santa Rosa Beach to Knoxville by taxi, plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Destin–Fort Walton Beach Airport, fly
best- Take the taxi from Santa Rosa Beach to Destin–Fort Walton Beach Airport (VPS)taxi
- Fly from Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS)plane VPS - TYS
2h 25m$223–757Drive 482.2 mi
cheapest- Drive from Santa Rosa Beach to Knoxvillecar 482.2 mi
9h 39m$88–128Taxi, bus via Jacksonville
- Take the taxi from Santa Rosa Beach to Crestviewtaxi
- Take the bus from Crestview to Tallahasseebus
- Take the bus from Tallahassee to Jacksonvillebus
- Take the bus from Jacksonville to New York City Chinatownbus
- Take the bus from New York, NY to Knoxville, TNbus Ny
41h 2m$445–635Taxi to Northwest Florida Beaches International Airport, fly
- Take the taxi from Santa Rosa Beach to Northwest Florida Beaches International Airport (ECP)taxi
- Fly from Northwest Florida Beaches International Airport (ECP) to Mcghee Tyson Airport (TYS)plane ECP - TYS
4h 16m$244–781Drive to Pensacola International Airport, fly
- Drive from Santa Rosa Beach to Pensacola-Airport-PNScar
- Fly from Pensacola International Airport (PNS) to Mcghee Tyson Airport (TYS)plane PNS - TYS
5h 12m$162–688Taxi, bus
- Take the taxi from Santa Rosa Beach to Crestviewtaxi
- Take the bus from Crestview to Tallahasseebus
- Take the bus from Tallahassee to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to New York Midtownbus
- Take the bus from New York to Knoxvillebus Nyc
42h 58m$494–738Taxi, bus, train
- Take the taxi from Santa Rosa Beach to Crestviewtaxi
- Take the bus from Crestview to Wildwoodbus
- Take the bus from Wildwood Amtrak Station to Jacksonvillebus
- Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York to Knoxvillebus Nyc
45h 11m$707–1,191
Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Santa Rosa Beach to Knoxville is to drive which costs $85 - $130 and takes 9h 39m.
The fastest way to get from Santa Rosa Beach to Knoxville is to taxi and fly which takes 2h 25m and costs $220 - $800.
The distance between Santa Rosa Beach and Knoxville is 441 miles. The road distance is 485 miles.
The best way to get from Santa Rosa Beach to Knoxville without a car is to taxi and bus via Jacksonville which takes 41h 2m and costs $440 - $650.
It takes approximately 2h 25m to get from Santa Rosa Beach to Knoxville, including transfers.
Knoxville is 1h ahead of Santa Rosa Beach. It is currently 12:44 PM in Santa Rosa Beach and 1:44 PM in Knoxville.
Yes, the driving distance between Santa Rosa Beach to Knoxville is 485 miles. It takes approximately 9h 39m to drive from Santa Rosa Beach to Knoxville.
There are 280+ hotels available in Knoxville.
What companies run services between Santa Rosa Beach, FL, USA and Knoxville, TN, USA?
There is no direct connection from Santa Rosa Beach to Knoxville. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take the taxi to Crestview, take the bus to Tallahassee, walk to N Monroe Street and Silver Slipper Lane, take the bus to C.K. Steele Plaza Gate 22, take the bus to Jacksonville, take the bus to New York City Chinatown, take the bus to Knoxville, TN, then take the taxi to Knoxville.
- Website
- delta.com
Flights from Destin–Fort Walton Beach Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–600
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $95–600
Flights from Pensacola International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $95–600
- Website
- aa.com
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $120–700
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 5h 54m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- $200–900
Flights from Pensacola International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $120–650
- Website
- southwest.com
Flights from Destin–Fort Walton Beach Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 3h 27m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h 33m
- When
- Saturday, Tuesday, Wednesday, and Sunday
- Estimated price
- $110–650
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Dallas
- Ave. Duration
- 6h 10m
- When
- Sunday and Saturday
- Estimated price
- $230–1,000
Flights from Pensacola International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h
- When
- Saturday
- Estimated price
- $110–650
- Website
- allegiantair.com
Flights from Destin–Fort Walton Beach Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 21m
- When
- Saturday, Thursday, and Sunday
- Estimated price
- $95–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 18h 39m
- Frequency
- Once daily
- Estimated price
- $300–650
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Crestview to Tallahassee
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
Bus from Crestview to Tallahassee
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
Bus from Crestview to Wildwood
- Ave. Duration
- 5h 52m
- Frequency
- Once daily
- Estimated price
- $75–95
- Schedules at
- omnibusexpress.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tallahassee to Jacksonville
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $24–50
- Website
- https://www.greyhound.com/
Bus from Tallahassee to Atlanta Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to New York City Chinatown
- Ave. Duration
- 18h 35m
- Frequency
- 6 times a week
- Estimated price
- $130–230
- Schedules at
- flixbus.com
Bus from Tallahassee to Atlanta Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to New York Midtown
- Ave. Duration
- 17h 25m
- Frequency
- Twice daily
- Estimated price
- $120–210
- Schedules at
- flixbus.com
- Phone
- +1 615-939-8887
- tennesseetravel@gotobus.com
- Website
- nytnbus.com
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- https://www.nytnbus.com
- Adult One-way
- $95–110
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $95–140
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $95–140
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Wildwood Amtrak Station to Jacksonville
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $45–70
- Website
- https://www.amtrak.com/home.html
- Ave. Duration
- 56 min
- Estimated price
- $70–130
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide










