There are 7 ways to get from Santa Rosa Beach to Knoxville by taxi, plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Destin–Fort Walton Beach Airport, fly
best- Take the taxi from Santa Rosa Beach to Destin–Fort Walton Beach Airport (VPS)
- Fly from Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS)VPS - TYS
2h 23m$218–707Drive 488.6 mi
cheapest- Drive from Santa Rosa Beach to Knoxville488.6 mi
9h 21m$90–129Taxi, bus, train
- Take the taxi from Santa Rosa Beach to Whataburger - Defuniak Springs
- Take the bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FL
- Take the bus from Gainesville to Jacksonville
- Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Station
- Take the bus from New York City to KnoxvilleNy
40h 48m$420–1,010Taxi to Northwest Florida Beaches International Airport, fly
- Take the taxi from Santa Rosa Beach to Northwest Florida Beaches International Airport (ECP)
- Fly from Northwest Florida Beaches International Airport (ECP) to Mcghee Tyson Airport (TYS)ECP - TYS
4h 13m$239–731Taxi, bus
- Take the taxi from Santa Rosa Beach to Whataburger - Defuniak Springs
- Take the bus from Whataburger - Defuniak Springs to Love's Travel Stop - Loxley
- Take the bus from Mobile to Atlanta
- Take the bus from Atlanta to New York
- Take the bus from New York City to KnoxvilleNy
42h 50m$312–595Taxi, bus, train via Wildwood
- Take the taxi from Santa Rosa Beach to Whataburger - Defuniak Springs
- Take the bus from Whataburger - Defuniak Springs to Mi Ranchito Restaurant - Ocala, FL
- Take the bus from Ocala to Wildwood
- Take the bus from Wildwood Amtrak Station to Jacksonville
- Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Station
- Take the bus from New York to KnoxvilleNyc
44h 12mTaxi, bus via Orlando
- Take the taxi from Santa Rosa Beach to Whataburger - Defuniak Springs
- Take the bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FL
- Take the bus from Gainesville to Orlando Bus Station
- Take the bus from Orlando Bus Station to New York City Chinatown
- Take the bus from New York City to KnoxvilleNy
47h 3m$370–697
Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Santa Rosa Beach to Knoxville is to drive which costs $85 - $130 and takes 9h 21m.
The fastest way to get from Santa Rosa Beach to Knoxville is to taxi and fly which takes 2h 23m and costs $210 - $750.
The distance between Santa Rosa Beach and Knoxville is 441 miles. The road distance is 491.5 miles.
The best way to get from Santa Rosa Beach to Knoxville without a car is to taxi and bus and train which takes 40h 48m and costs $420 - $1,100.
It takes approximately 2h 23m to get from Santa Rosa Beach to Knoxville, including transfers.
Knoxville is 1h ahead of Santa Rosa Beach. It is currently 7:03 AM in Santa Rosa Beach and 8:03 AM in Knoxville.
Yes, the driving distance between Santa Rosa Beach to Knoxville is 491 miles. It takes approximately 9h 21m to drive from Santa Rosa Beach to Knoxville.
There are 270+ hotels available in Knoxville.
What companies run services between Santa Rosa Beach, FL, USA and Knoxville, TN, USA?
There is no direct connection from Santa Rosa Beach to Knoxville. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take the taxi to Whataburger - Defuniak Springs, take the bus to Circle K - Gainesville, FL, take the taxi to Gainesville, take the bus to Jacksonville, walk to JRTC Bay H, take the line 4 bus to Amtrak Station, walk to Jacksonville, take the train to Ny Moynihan Train Hall At Penn Station, walk to 34 St-Herald Sq, take the subway to East Broadway, walk to New York City, take the bus to Knoxville, then take the taxi to Knoxville.
- Website
- delta.com
Flights from Destin–Fort Walton Beach Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- $90–550
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- $90–550
- Website
- aa.com
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $110–650
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 5h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–800
- Website
- allegiantair.com
Flights from Destin–Fort Walton Beach Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 20m
- When
- Thursday
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Northwest Florida Beaches International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 18h 7m
- Frequency
- Once daily
- Estimated price
- $130–550
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $60–170
- Schedules at
- tornadobus.com
- Adults 11-59
- $60–170
Bus from Whataburger - Defuniak Springs to Love's Travel Stop - Loxley
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Whataburger - Defuniak Springs to Mi Ranchito Restaurant - Ocala, FL
- Ave. Duration
- 4h 27m
- Frequency
- Once daily
- Estimated price
- $65–180
- Schedules at
- tornadobus.com
- Adults 11-59
- $65–180
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $16–22
- Schedules at
- flixbus.com
Bus from Gainesville to Orlando Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- $26–45
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to New York City Chinatown
- Ave. Duration
- 21h 25m
- Frequency
- 5 times a week
- Estimated price
- $110–270
- Schedules at
- flixbus.com
- Phone
- +1 615-939-8887
- jpan12692@gmail.com
- Website
- nytnbus.com
Bus from New York City to Knoxville
- Ave. Duration
- 12h
- Frequency
- 3 times a week
- Estimated price
- $80–100
- Schedules at
- nytnbus.com
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Mobile to Atlanta
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- $70–95
- Schedules at
- omnibusexpress.com
Bus from Ocala to Wildwood
- Ave. Duration
- 25 min
- Frequency
- Once daily
- Estimated price
- $35–50
- Schedules at
- omnibusexpress.com
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Atlanta to New York
- Ave. Duration
- 16h 30m
- Frequency
- 3 times a day
- Estimated price
- $30–150
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- 3 times a week
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Wildwood Amtrak Station to Jacksonville
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Ave. Duration
- 39 min
- Estimated price
- $70–120
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