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There are 10 ways to get from Santa Maria di Leuca to Sicily by bus, ferry, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus

  1. Take the bus from Santa Maria di Leuca to Maglie
  2. Take the bus from Maglie Megapark Via Otranto to Messina - Piazza della Repubblica
  3. Take the bus from Messina Piazza della Repubblica to Palermo

Cheapest option

Bus to Brindisi, fly to Palermo

  1. Take the bus from Santa Maria di Leuca - Incrocio Santuario to Lecce - Camera di Commercio/Stazione
  2. Fly from Brindisi (BDS) to Palermo (PMO)

8 alternative options

Bus, ferry, train

  1. Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Gallipoli - Parcheggio cimitero
  2. Take the bus from Gallipoli - Piazza Cimitero to Taranto
  3. Take the Bus from Taranto to Villa San Giovanni
  4. Take the ferry from Villa San Giovanni to Messina Marittima
  5. Take the train from Messina Centrale to Palermo Centrale

Bus via Cosenza

  1. Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Gallipoli - Parcheggio cimitero
  2. Take the bus from Gallipoli - Piazza Cimitero to Cosenza
  3. Take the bus from Cosenza to Messina
  4. Take the bus from Messina - Piazza della Repubblica to Palermo - via Fazello

Bus, train

  1. Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Gallipoli - Parcheggio cimitero
  2. Take the bus from Gallipoli to Messina - Piazza della Repubblica
  3. Take the train from Messina Centrale to Palermo Centrale

Drive, ferry

  1. Drive from Santa Maria di Leuca to Villa San Giovanni
  2. Take the ferry from Villa San Giovanni to Messina Marittima
  3. Drive from Messina Marittima to Palermo

Bus to Brindisi, fly to Catania

  1. Take the bus from Santa Maria di Leuca - Incrocio Santuario to Lecce - Camera di Commercio/Stazione
  2. Fly from Brindisi (BDS) to Catania (CTA)

Bus, train to Bari, fly to Catania

  1. Take the bus from Santa Maria di Leuca - Incrocio Santuario to Lecce - Camera di Commercio/Stazione
  2. Take the train from Lecce to Bari Centrale
  3. Fly from Bari (BRI) to Catania (CTA)

Bus, train to Bari, fly to Palermo

  1. Take the bus from Santa Maria di Leuca - Incrocio Santuario to Lecce - Camera di Commercio/Stazione
  2. Take the train from Lecce to Bari Centrale
  3. Fly from Bari (BRI) to Palermo (PMO)

Bus to Brindisi, fly to Trapani

  1. Take the bus from Santa Maria di Leuca - Incrocio Santuario to Lecce - Camera di Commercio/Stazione
  2. Fly from Brindisi (BDS) to Trapani (TPS)

Santa Maria di Leuca to Sicily by bus and walk

The journey time between Santa Maria di Leuca and Sicily is around 42h 50m and covers a distance of around 877 km. This includes an average layover time of around 30h 30m. The fastest journey normally takes 42h 50m. Operated by S.T.P. di Terra d' Otranto, SAIS trasporti S.p.A. - Autolinee Giamporcaro and Autoservizi Salemi Srl, the Santa Maria di Leuca to Sicily service departs from Santa Maria di Leuca and arrives in Palermo. Typically three services run weekly, although weekend and holiday schedules can vary so check in advance.

Explore all travel options

Average journey times

Time on transportation:
12h 20m
Layover time:
30h 30m
Total time:
42h 50m

Route information

Fastest journey time:
42h 50m
Journey distance:
877 km
Services per week:
3
Cheapest price:
€46
Carbon emissions:
109 kg CO2

First and last service

First service departs at:
12:55
Last service departs at:
12:55

The schedules shown below are for the next available departures.

Santa Maria di Leuca to Sicily bus and walk schedules

Santa Maria di Leuca → Sicily
Partially open

Travel safe during COVID-19

Rules to follow in Italy

1.5m

Mandatory

Mandatory

Travel within Italy

Observe COVID-19 safety rules
Nationwide control measures in place
Inter-regional travel is permitted
Health pass is required for long-distance travel by plane, train or coach, as well as in some public venues

COVID-19 help in Italy

If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 1500

Frequently Asked Questions


There are currently travel restrictions within Italy.

Explore options for future travel

Domestic travel is not restricted, but some conditions may apply

  • Face masks are mandatory
  • There is a social distancing requirement of 1.5 metres
  • Observe COVID-19 safety rules
  • Nationwide control measures in place
  • Inter-regional travel is permitted
  • Health pass is required for long-distance travel by plane, train or coach, as well as in some public venues

Explore travel options

The national COVID-19 helpline number in Sicily is 1500.

Wearing a face mask on public transport in Sicily is mandatory.

The social distance requirement in Sicily is 1.5 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 1500.

Last updated: 27 Sep 2021
Exceptions may apply, for full details: European Union.

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Santa Maria di Leuca to Sicily is to bus which costs €45 - €75 and takes 14h 30m.

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The quickest way to get from Santa Maria di Leuca to Sicily is to bus and fly which costs €28 - €190 and takes 6h 46m.

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No, there is no direct bus from Santa Maria di Leuca to Sicily. However, there are services departing from Santa Maria di Leuca and arriving at Palermo via Maglie Megapark Via Otranto and Messina Piazza della Repubblica. The journey, including transfers, takes approximately 14h 30m.

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The distance between Santa Maria di Leuca and Sicily is 440 km.

The best way to get from Santa Maria di Leuca to Sicily without a car is to bus which takes 14h 30m and costs €45 - €75.

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It takes approximately 14h 30m to get from Santa Maria di Leuca to Sicily, including transfers.

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Santa Maria di Leuca to Sicily bus services, operated by S.T.P. di Terra d' Otranto, depart from Santa Maria di Leuca station.

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The quickest flight from Brindisi Airport to Palermo Airport is the direct flight which takes 1h 15m.

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Santa Maria di Leuca to Sicily bus services, operated by Autoservizi Salemi Srl, arrive at Palermo station.

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Alitalia and Ryanair offer flights from Brindisi Airport to Palermo Airport.

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Map of how to get from Santa Maria di Leuca to Sicily.
Launch map view
  • Distance: 439.8 km
  • Duration: 14h 30m

What companies run services between Santa Maria di Leuca, Italy and Sicily, Italy?

You can take a bus from Santa Maria di Leuca to Palermo via Maglie, Maglie Megapark Via Otranto, Messina - Piazza della Repubblica, and Messina Piazza della Repubblica in around 14h 30m.

Airlines
Ryanair
Website
ryanair.com
Flights from Brindisi to Palermo
Ave. Duration
1h 15m
When
Wednesday and Sunday
Estimated price
€20 - €200
Flights from Brindisi to Palermo via Rome
Ave. Duration
3h 15m
When
Sunday
Estimated price
€20 - €200
Flights from Brindisi to Catania via Rome
Ave. Duration
3h 52m
When
Wednesday and Sunday
Estimated price
€20 - €160
Flights from Brindisi to Catania via Bologna
Ave. Duration
4h 30m
When
Monday and Friday
Estimated price
€20 - €160
Flights from Brindisi to Catania via Venice
Ave. Duration
4h 5m
When
Monday
Estimated price
€20 - €160
Flights from Brindisi to Catania via Milan Bergamo
Ave. Duration
4h 40m
When
Monday, Friday and Sunday
Estimated price
€20 - €160
Flights from Brindisi to Catania via Pisa
Ave. Duration
5h 20m
When
Monday, Wednesday, Thursday, Friday and Saturday
Estimated price
€20 - €160
Flights from Brindisi to Catania via Turin
Ave. Duration
6h
When
Monday, Tuesday and Thursday
Estimated price
€20 - €160
Flights from Brindisi to Catania via Milan Malpensa
Ave. Duration
6h 15m
When
Tuesday, Wednesday and Thursday
Estimated price
€20 - €160
Flights from Bari to Catania
Ave. Duration
1h 10m
When
Monday, Thursday, Friday and Sunday
Estimated price
€14 - €170
Flights from Bari to Catania via Rome
Ave. Duration
3h 20m
When
Tuesday, Wednesday, Friday, Saturday and Sunday
Estimated price
€14 - €170
Flights from Bari to Palermo
Ave. Duration
1h 15m
When
Wednesday, Friday and Sunday
Estimated price
€18 - €180
Flights from Bari to Palermo via Rome
Ave. Duration
3h 30m
When
Wednesday, Friday and Saturday
Estimated price
€18 - €180
Alitalia
Website
alitalia.com
Flights from Brindisi to Palermo via Rome
Ave. Duration
3h 5m
When
Every day
Estimated price
€110 - €280
Flights from Brindisi to Catania via Rome
Ave. Duration
4h
When
Every day
Estimated price
€110 - €260
Flights from Brindisi to Catania via Milan Linate
Ave. Duration
7h 40m
When
Every day
Estimated price
€110 - €260
Flights from Bari to Catania via Rome
Ave. Duration
3h 10m
When
Every day
Estimated price
€75 - €260
Flights from Bari to Palermo via Rome
Ave. Duration
3h 15m
When
Every day
Estimated price
€75 - €240
easyJet
Website
easyjet.com
Flights from Brindisi to Catania via Milan Malpensa
Ave. Duration
4h 58m
When
Monday, Tuesday, Thursday and Friday
Estimated price
€100 - €290
Wizz Air
Website
wizzair.com
Flights from Brindisi to Catania via Bologna
Ave. Duration
4h 5m
When
Monday, Wednesday, Friday and Sunday
Estimated price
€23 - €160
Flights from Brindisi to Catania via Milan Malpensa
Ave. Duration
6h 30m
When
Monday, Wednesday, Friday and Sunday
Estimated price
€23 - €160
Volotea
Website
volotea.com
Flights from Bari to Catania
Ave. Duration
1h 15m
When
Monday
Estimated price
€35 - €240
Flights from Bari to Palermo
Ave. Duration
1h 15m
When
Monday and Saturday
Estimated price
€23 - €160
Transavia France
Website
transavia.com
Flights from Brindisi to Catania via Paris Orly
Ave. Duration
7h 45m
When
Friday
Estimated price
€95 - €550
Alba Star
Website
albastar.es
Flights from Brindisi to Trapani
Ave. Duration
1h 10m
When
Tuesday and Friday
Estimated price
€90 - €160
Train operators
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Messina Centrale to Palermo Centrale
Ave. Duration
2h 52m
Frequency
Every 4 hours
Estimated price
€15 - €30
Website
Trenitalia
1st Class
€27 - €30
Train from Lecce to Bari Centrale
Ave. Duration
1h 54m
Frequency
Hourly
Estimated price
€10 - €21
Website
Trenitalia
1st Class
€19 - €21
Frequently asked questions
Is there Wi-Fi on Trenitalia?
Yes - Wi-Fi is available on both Frecciarossa and Frecciargento services, and may be accessed free of charge. Services require either a mobile phone number or credit card for verification purposes and allow access for 24 hours.
Are there power outlets on Trenitalia?
Yes - Frecce services include a power socket for each seat.
Does Trenitalia offer meals or snacks?
Yes - Frecciarossa and Frecciargento services often offer bar and restaurant options, though this depends on the individual route and train type. Business, Premium and First Class tickets include a complimentary drink and snack. Some services may offer restaurant, FRECCIABistro or pre-booked, in-seat meal options. Please check your service as options vary.
For more information, please visit this page
Trenitalia Intercity

Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Messina Centrale to Palermo Centrale
Ave. Duration
3h
Frequency
Twice daily
Estimated price
€14 - €20
Website
Trenitalia Intercity
2nd Class
€14 - €20
Train from Lecce to Bari Centrale
Ave. Duration
1h 40m
Frequency
3 times a day
Estimated price
€10 - €15
Website
Trenitalia Intercity
2nd Class
€10 - €15
Trenitalia Frecce

Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Lecce to Bari Centrale
Ave. Duration
1h 18m
Frequency
Every 3 hours
Estimated price
€14 - €55
Website
Trenitalia Frecce
Super Economy
€14 - €20
Base Standard
€30 - €45
Base Premium
€35 - €55
Bus operators
SAIS trasporti S.p.A. - Autolinee Giamporcaro
Phone
091 617 1141
Website
saistrasporti.it
Bus from Maglie Megapark Via Otranto to Messina - Piazza della Repubblica
Ave. Duration
7h 55m
Frequency
3 times a day
Estimated price
€30 - €50
Schedules at
saistrasporti.it
Bus from Gallipoli to Messina - Piazza della Repubblica
Ave. Duration
10h 25m
Frequency
3 times a day
Estimated price
€35 - €55
Schedules at
saistrasporti.it
Autoservizi Salemi Srl
Phone
(+39) 0923 98.11.20
Website
autoservizisalemi.it
Bus from Messina Piazza della Repubblica to Palermo
Ave. Duration
3h 5m
Frequency
Once daily
Estimated price
€13 - €19
Schedules at
autoservizisalemi.it
Bus from Taranto to Villa San Giovanni
Ave. Duration
4h 35m
Frequency
Once daily
Estimated price
€18 - €29
Schedules at
autoservizisalemi.it
Salento in bus
Phone
+39 800 242 815, 344/2274620
Email
salentoinbus@provincia.le.it
Website
provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Gallipoli - Parcheggio cimitero
Ave. Duration
1h 19m
Frequency
Every 2 hours
Estimated price
€2 - €5
Schedules at
provincia.le.it
Bus from Santa Maria di Leuca - Incrocio Santuario to Lecce - Camera di Commercio/Stazione
Ave. Duration
2h
Frequency
5 times a day
Estimated price
€2 - €7
Schedules at
provincia.le.it
InterSaj
Phone
0981 500331
Email
info@saj.it
Website
saj.it
Bus from Gallipoli - Piazza Cimitero to Taranto
Ave. Duration
2h 10m
Frequency
6 times a week
Estimated price
€11 - €18
Schedules at
saj.it
Bus from Gallipoli - Piazza Cimitero to Cosenza
Ave. Duration
5h 40m
Frequency
6 times a week
Estimated price
€22 - €35
Schedules at
saj.it
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 30 300 137 300
Email
service@flixbus.xom
Website
flixbus.de
Bus from Cosenza to Messina
Ave. Duration
3h 50m
Frequency
Twice daily
Estimated price
€12 - €16
Website
flixbus.co.uk
Frequently asked questions
Is there Wi-Fi on FlixBus?
Yes - FlixBus offers free Wi-Fi
Are there power outlets on FlixBus?
Yes
Does FlixBus offer meals or snacks?
Yes - snacks and drinks may be purchased from the driver. Please note, this is not available on all services.
For more information, please visit this page
SAIS Autolinee
Phone
800 21 10 20
Email
saisautolineeweb@gmail.com
Website
saisautolinee.it
Bus from Messina - Piazza della Repubblica to Palermo - via Fazello
Ave. Duration
2h 50m
Frequency
4 times a day
Estimated price
€12 - €17
Schedules at
saisautolinee.it
Ferry operators
Blue Jet
Phone
342 32 55 869
Website
blujetlines.it
Ferry from Villa San Giovanni to Messina Marittima
Ave. Duration
20 min
Frequency
Hourly
Estimated price
€3
Schedules at
blujetlines.it
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
Ave. Duration
20 min
Frequency
Hourly
Website
Trenitalia
Frequently asked questions
Is there Wi-Fi on Trenitalia?
Yes - Wi-Fi is available on both Frecciarossa and Frecciargento services, and may be accessed free of charge. Services require either a mobile phone number or credit card for verification purposes and allow access for 24 hours.
Are there power outlets on Trenitalia?
Yes - Frecce services include a power socket for each seat.
Does Trenitalia offer meals or snacks?
Yes - Frecciarossa and Frecciargento services often offer bar and restaurant options, though this depends on the individual route and train type. Business, Premium and First Class tickets include a complimentary drink and snack. Some services may offer restaurant, FRECCIABistro or pre-booked, in-seat meal options. Please check your service as options vary.
For more information, please visit this page

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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