There are 8 ways to get from Santa Fe to Mexicali by plane, bus, train, shuttle or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Santa Fe to Yuma, bus  •  8 h 56 min

  1. Fly from Santa Fe (SAF) to Yuma (YUM) SAF - YUM
  2. Take the bus from San Luis Rio Colorado to Mexicali Bus Terminal

$252 - $1,156

Cheapest option

Train, bus via Flagstaff, Az  •  17 h 25 min

  1. Take the train from Santa Fe Depot to Downtown Albuquerque
  2. Take the train from Albuquerque Alvarado Transportation Center to Flagstaff Amtrak
  3. Take the bus from Flagstaff, Az to Phoenix, Az
  4. Take the bus from Phoenix, Az to Calexico, Ca

$123 - $341

6 alternative options

Fly Albuquerque to San Diego, bus  •  8 h 25 min

  1. Fly from Albuquerque (ABQ) to San Diego (SAN) ABQ - SAN
  2. Take the bus from Tijuana to Mexicali

$188 - $441

Fly Albuquerque to Yuma, bus  •  8 h 48 min

  1. Fly from Albuquerque (ABQ) to Yuma (YUM) ABQ - YUM
  2. Take the bus from San Luis Rio Colorado to Mexicali Bus Terminal

$208 - $901

Bus  •  19 h 58 min

  1. Take the bus from Santa Fe to El Paso, TX
  2. Take the bus from El Paso, Tx to Phoenix, Az
  3. Take the bus from Phoenix, Az to Calexico, Ca

$138 - $307

Train, shuttle, bus  •  23 h 5 min

  1. Take the train from Santa Fe Depot to Downtown Albuquerque
  2. Take the train from Albuquerque Alvarado Transportation Center to Flagstaff Amtrak
  3. Take a shuttle bus from Flagstaff, AZ to Phoenix Sky Harbor Airport, AZ
  4. Take the bus from Phoenix to Mexicali

$160 - $320

Train, bus  •  25 h 33 min

  1. Take the train from Santa Fe Depot to Downtown Albuquerque
  2. Take the train from Albuquerque Alvarado Transportation Center to Fullerton Transportation Center
  3. Take the train from Fullerton Transportation Center to San Diego Santa Fe Depot
  4. Take the bus from Tijuana to Mexicali

$166 - $441

Drive  •  11 h 50 min

  1. Drive from Santa Fe to Mexicali 766.1 miles

$100 - $150

Questions & Answers

The cheapest way to get from Santa Fe to Mexicali is to drive which costs $100 - $150 and takes 11 h 50 min.

More details

The quickest way to get from Santa Fe to Mexicali is to fly and bus which costs $180 - $450 and takes 8 h 25 min.

More details

The distance between Santa Fe and Mexicali is 587 miles. The road distance is 766.1 miles.

Get driving directions

The best way to get from Santa Fe to Mexicali without a car is to train and bus which takes 17 h 25 min and costs $120 - $350.

More details

It takes approximately 8 h 56 min to get from Santa Fe to Mexicali, including transfers.

More details

There is no direct flight from Santa Fe Airport to Yuma Airport. The quickest flight takes 5 h 12 min and has one stopover.

Search flights

Mexicali is 1 h behind Santa Fe. It is currently 7:32 AM in Santa Fe and 6:32 AM in Mexicali.

Yes, the driving distance between Santa Fe to Mexicali is 766 miles. It takes approximately 11 h 50 min to drive from Santa Fe to Mexicali.

Get driving directions

American Airlines offers flights from Santa Fe Airport to Yuma Airport.

Search flights

There are 45+ hotels available in Mexicali. Prices start at $39 USD per night.

More details

Map of how to get from Santa Fe to Mexicali.
Launch map view
  • Distance: 586.8 miles
  • Duration: 8 h 56 min

What companies run services between Santa Fe, NM, USA and Mexicali, Mexico?

You can take a bus from Santa Fe to Mexicali via Santa Fe, El Paso, TX, El Paso, Tx, Phoenix, Az, Calexico, Ca, and Calexico,CA in around 19 h 58 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Albuquerque to San Diego
Ave. Duration
1 h 49 min
When
Every day
Estimated price
$310 - $700
Flights from Albuquerque to San Diego via Phoenix
Ave. Duration
3 h 29 min
When
Every day
Estimated price
$310 - $700
Flights from Albuquerque to San Diego via Las Vegas
Ave. Duration
3 h 37 min
When
Monday to Friday
Estimated price
$310 - $700
American Airlines
Website
aa.com
Flights from Santa Fe to Yuma via Phoenix
Ave. Duration
5 h 12 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,100
Flights from Santa Fe to Yuma via Dallas/Ft.Worth, Phoenix
Ave. Duration
10 h 32 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,200
Flights from Albuquerque to San Diego via Phoenix
Ave. Duration
3 h 40 min
When
Every day
Estimated price
$260 - $700
Flights from Albuquerque to San Diego via Los Angeles
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$260 - $700
Flights from Albuquerque to Yuma via Phoenix
Ave. Duration
4 h 21 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $850
Alaska Airlines, Inc.
Website
alaskaair.com
Flights from Albuquerque to San Diego
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$490 - $1,400
Flights from Albuquerque to San Diego via Phoenix
Ave. Duration
3 h 40 min
When
Every day
Estimated price
$260 - $700
Flights from Albuquerque to San Diego via Los Angeles
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$260 - $700
Flights from Albuquerque to Yuma via Phoenix
Ave. Duration
4 h 21 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $850
Flights from Albuquerque to Yuma via Santa Ana, Phoenix
Ave. Duration
6 h 51 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $850
Train operators
Rio Metro Regional Transit District
Phone
1-866-795-7245
Email
riometro@mrcog-nm.gov
Website
riometro.org
Train from Santa Fe Depot to Downtown Albuquerque
Ave. Duration
1 h 32 min
Frequency
Every 4 hours
Estimated price
$7 - $11
Schedules at
riometro.org
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Albuquerque Alvarado Transportation Center to Flagstaff Amtrak
Ave. Duration
5 h 16 min
Frequency
Twice daily
Estimated price
$55 - $160
Website
amtrak.com
Coach Seat
$55 - $85
Flexi Coach Seat
$100 - $150
Business Coach Seat
$100 - $160
Room
$260 - $360
Train from Albuquerque Alvarado Transportation Center to Fullerton Transportation Center
Ave. Duration
15 h 38 min
Frequency
Twice daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Train from Fullerton Transportation Center to San Diego Santa Fe Depot
Ave. Duration
2 h 23 min
Frequency
Every 2 hours
Estimated price
$30 - $65
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $65
Room
$160 - $220
Bus operators
ABC
Website
abc.com.mx
Bus from San Luis Rio Colorado to Mexicali Bus Terminal
Ave. Duration
1 h 15 min
Frequency
Every 2 hours
Estimated price
$6 - $10
Schedules at
reservamos.mx
Book at
reservamos.mx
Bus from Tijuana to Mexicali
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$15 - $22
Schedules at
reservamos.mx
Book at
reservamos.mx
Tufesa
Phone
7022546899
Email
serviciosvegas@hotmail.com
Website
tufesabus.com
Bus from San Luis Río Colorado to Mexicali Bus Terminal
Ave. Duration
54 min
Frequency
Every 4 hours
Estimated price
$6 - $14
Book at
GotoBus
Plus
$6 - $10
Platinum
$11 - $14
Ejecutivo
$10 - $14
Aguacaliente
Phone
6646212955
Email
atencionaclientes@autobusesaguacaliente.com.mx
Website
autobusesaguacaliente.com.mx
Bus from Tijuana to Mexicali
Ave. Duration
2 h
Frequency
Every 2 hours
Estimated price
$18
Schedules at
autobusesaguacaliente.com.mx
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Flagstaff, Az to Phoenix, Az
Ave. Duration
2 h 35 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Phoenix, Az to Calexico, Ca
Ave. Duration
4 h 35 min
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from El Paso, Tx to Phoenix, Az
Ave. Duration
6 h 50 min
Frequency
Hourly
Estimated price
$45 - $110
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $110
EPLA Limo Express
Website
eplalimo.com
Bus from Santa Fe to El Paso, TX
Ave. Duration
5 h 45 min
Frequency
Twice daily
Estimated price
$35 - $55
Schedules at
eplalimo.com
Arizona Shuttle
Phone
+1 (800) 888-2749
Website
arizonashuttle.com
Shuttle from Flagstaff, AZ to Phoenix Sky Harbor Airport, AZ
Ave. Duration
3 h 10 min
Frequency
Hourly
Estimated price
$45 - $70
Schedules at
arizonashuttle.com
Greyhound Mexico
Phone
01-800 890 6821
Website
greyhound.com.mx
Bus from Phoenix to Mexicali
Ave. Duration
9 h 50 min
Frequency
Once daily
Estimated price
$50 - $75
Schedules at
greyhound.com.mx

Want to know more about travelling around Mexico

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The best way to get from Santa Fe to Santa Fe Airport is to taxi which takes 17 min and costs $30 - $40.

More details