There are 7 ways to get from Santa Fe to Mexicali by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Santa Fe to Yuma, bus  •  9 h 22 min

  1. Fly from Santa Fe (SAF) to Yuma (YUM) SAF - YUM
  2. Take the bus from San Luis Rio Colorado to Mexicali Bus Terminal

$252 - $1,155

Cheapest option

Train, bus via Flagstaff Amtrak  •  19 h 10 min

  1. Take the train from Santa Fe Depot to Downtown Albuquerque
  2. Take the train from Albuquerque Alvarado Transportation Center to Flagstaff Amtrak
  3. Take the bus from Flagstaff, AZ to Phoenix Sky Harbor Airport, AZ
  4. Take the bus from Phoenix Sky Harbor Airport, AZ to Yuma, AZ
  5. Take the bus from San Luis Río Colorado to Mexicali Bus Terminal

$164 - $306

5 alternative options

Fly Albuquerque to San Diego, bus  •  8 h 20 min

  1. Fly from Albuquerque (ABQ) to San Diego (SAN) ABQ - SAN
  2. Take the bus from Tijuana to Mexicali

$187 - $439

Fly Albuquerque to Yuma, bus  •  9 h 46 min

  1. Fly from Albuquerque (ABQ) to Yuma (YUM) ABQ - YUM
  2. Take the bus from San Luis Rio Colorado to Mexicali Bus Terminal

$208 - $900

Train, bus  •  24 h 53 min

  1. Take the train from Santa Fe Depot to Downtown Albuquerque
  2. Take the train from Albuquerque Alvarado Transportation Center to Fullerton Transportation Center
  3. Take the train from Fullerton Transportation Center to San Diego Santa Fe Depot Amtrak
  4. Take the bus from Tijuana to Mexicali

$165 - $439

Train, bus via Las Cruces, Nm  •  27 h 56 min

  1. Take the train from Lamy Amtrak to Raton Amtrak
  2. Take the bus from Raton to Las Cruces, Nm
  3. Take the bus from Las Cruces, Nm to Phoenix, Az
  4. Take the bus from Phoenix, Az to Calexico, Ca

$175 - $475

Drive  •  11 h 50 min

  1. Drive from Santa Fe to Mexicali 766.1 miles

$100 - $150

Questions & Answers

The cheapest way to get from Santa Fe to Mexicali is to drive which costs $100 - $150 and takes 11 h 50 min.

More details

The quickest way to get from Santa Fe to Mexicali is to fly and bus which takes 8 h 20 min and costs $180 - $440.

More details

The distance between Santa Fe and Mexicali is 939 km. The road distance is 1226 km.

Get driving directions

It takes approximately 9 h 22 min to get from Santa Fe to Mexicali, including transfers.

More details

What companies run services between Santa Fe, NM, USA and Mexicali, Mexico?

There is no direct connection from Santa Fe to Mexicali. However, you can take the taxi to Santa Fe airport, fly to Yuma, take the walk to 32nd Street @ Pacific Avenue, take the line 4 bus to 24th Street @ Avenue A, take the line 95 bus to 2nd Ave and B Street, take the walk to San Luis Rio Colorado, then take the bus to Mexicali. Alternatively, you can take the shuttle to Albuquerque International Airport, NM, take the walk to Albuquerque airport, fly to San Diego, take the walk to Lindbergh Field & Terminal 1, take the line 992 bus to Broadway & Kettner Bl, take the walk to America Plaza Station, take the tram to San Ysidro/Intl Border, take the walk to Tijuana, then take the bus to Mexicali.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Albuquerque to San Diego
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$310 - $700
Flights from Albuquerque to San Diego via Phoenix
Ave. Duration
3 h 28 min
When
Saturday and Sunday
Estimated price
$310 - $700
Flights from Albuquerque to San Diego via Las Vegas
Ave. Duration
3 h 34 min
When
Every day
Estimated price
$310 - $700
American Airlines
Website
aa.com
Flights from Santa Fe to Yuma via Phoenix
Ave. Duration
5 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,100
Flights from Santa Fe to Yuma via Dallas/Ft.Worth, Phoenix
Ave. Duration
10 h 18 min
When
Every day
Estimated price
$300 - $1,200
Flights from Albuquerque to Yuma via Phoenix
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$170 - $850
Alaska Airlines, Inc.
Website
alaskaair.com
Flights from Albuquerque to San Diego
Ave. Duration
2 h 7 min
When
Every day
Estimated price
$490 - $1,400
Flights from Albuquerque to Yuma via Phoenix
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$170 - $850
Flights from Albuquerque to Yuma via Santa Ana, Phoenix
Ave. Duration
6 h 49 min
When
Every day
Estimated price
$190 - $850
Train operators
Rio Metro Regional Transit District
Phone
1-866-795-7245
Email
riometro@mrcog-nm.gov
Website
riometro.org
Train from Santa Fe Depot to Downtown Albuquerque
Ave. Duration
1 h 32 min
Frequency
Every 4 hours
Estimated price
$7 - $11
Schedules at
riometro.org
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Albuquerque Alvarado Transportation Center to Flagstaff Amtrak
Ave. Duration
5 h 6 min
Frequency
Twice daily
Estimated price
$55 - $160
Website
amtrak.com
Coach Seat
$55 - $85
Flexi Coach Seat
$100 - $150
Business Coach Seat
$100 - $160
Room
$260 - $360
Train from Albuquerque Alvarado Transportation Center to Fullerton Transportation Center
Ave. Duration
14 h 59 min
Frequency
Twice daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Train from Fullerton Transportation Center to San Diego Santa Fe Depot Amtrak
Ave. Duration
2 h 23 min
Frequency
Every 2 hours
Estimated price
$30 - $65
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $65
Room
$160 - $220
Train from Lamy Amtrak to Raton Amtrak
Ave. Duration
3 h 33 min
Frequency
Twice daily
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $60
Flexi Coach Seat
$65 - $100
Business Coach Seat
$65 - $90
Room
$190 - $270
Bus operators
ABC
Website
abc.com.mx
Bus from San Luis Rio Colorado to Mexicali Bus Terminal
Ave. Duration
1 h 15 min
Frequency
Every 2 hours
Estimated price
$6 - $9
Schedules at
reservamos.mx
Book at
reservamos.mx
Bus from Tijuana to Mexicali
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$14 - $20
Schedules at
reservamos.mx
Book at
reservamos.mx
Tufesa
Phone
016444102444
Website
tufesa.com.mx
Bus from San Luis Río Colorado to Mexicali Bus Terminal
Ave. Duration
54 min
Frequency
Every 4 hours
Estimated price
$6 - $13
Schedules at
tufesa.com.mx
Plus
$6 - $9
Platinum
$10 - $13
Ejecutivo
$9 - $13
Aguacaliente
Phone
6646212955
Email
atencionaclientes@autobusesaguacaliente.com.mx
Website
autobusesaguacaliente.com.mx
Bus from Tijuana to Mexicali
Ave. Duration
2 h
Frequency
Every 2 hours
Estimated price
$16
Schedules at
autobusesaguacaliente.com.mx
Arizona Shuttle
Phone
+1 (800) 888-2749
Website
arizonashuttle.com
Bus from Flagstaff, AZ to Phoenix Sky Harbor Airport, AZ
Ave. Duration
3 h 10 min
Frequency
Hourly
Estimated price
$30 - $50
Schedules at
arizonashuttle.com
1st Class Shuttle
Website
1stclassshuttle.com
Bus from Phoenix Sky Harbor Airport, AZ to Yuma, AZ
Ave. Duration
3 h 45 min
Frequency
3 times a day
Estimated price
$60 - $70
Schedules at
1stclassshuttle.com
Book at
shuttleyuma.hudsonltd.net
TAP
Website
tap.com.mx
Bus from San Luis Río Colorado to Mexicali Bus Terminal
Ave. Duration
1 h 20 min
Frequency
Every 30 minutes
Estimated price
$9 - $13
Schedules at
tap.com.mx
Confort
$9 - $13
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Raton to Las Cruces, Nm
Ave. Duration
8 h 5 min
Frequency
Every 3 hours
Estimated price
$45 - $120
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $120
Bus from Las Cruces, Nm to Phoenix, Az
Ave. Duration
6 h 25 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$75 - $110
Bus from Phoenix, Az to Calexico, Ca
Ave. Duration
4 h 35 min
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70

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