There are 5 ways to get from Santa Cruz de la Sierra to Uyuni by plane, bus, car or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  2 h 50 min

  1. Fly from Santa Cruz (VVI) to Uyuni (UYU) VVI - UYU

$120 - $293

Cheapest option

Bus Autotransportes Tupiza  •  22 h

  1. Take the bus from Santa Cruz de la Sierra to Potosí
  2. Take the bus from Potosi to Uyuni

$22 - $26

3 alternative options

Bus, drive, train  •  21 h 40 min

  1. Take the bus from Santa Cruz de la Sierra - Terminal Bimodal to Cochabamba
  2. Take the bus from Cochabamba to Provincia Arque
  3. Drive from Provincia Arque to Oruro
  4. Take the train from Oruro to Uyuní

$51 - $79

Bus Trans Caminante SRL  •  22 h 30 min

  1. Take the bus from Santa Cruz - Terminal Bimodal to Sucre
  2. Take the bus from Sucre to Uyuni

$28 - $36

Drive  •  14 h 48 min

  1. Drive from Santa Cruz de la Sierra to Uyuni 529.6 miles

$40 - $60

Questions & Answers

The cheapest way to get from Santa Cruz de la Sierra to Uyuni is to bus which costs $22 - $26 and takes 22 h.

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The quickest way to get from Santa Cruz de la Sierra to Uyuni is to fly which costs $120 - $300 and takes 2 h 50 min.

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No, there is no direct bus from Santa Cruz de la Sierra to Uyuni. However, there are services departing from Santa Cruz de la Sierra and arriving at Uyuni via Potosi. The journey, including transfers, takes approximately 22 h.

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The distance between Santa Cruz de la Sierra and Uyuni is 485 km. The road distance is 847.4 km.

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The best way to get from Santa Cruz de la Sierra to Uyuni without a car is to bus which takes 22 h and costs $22 - $26.

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It takes approximately 2 h 50 min to get from Santa Cruz de la Sierra to Uyuni, including transfers.

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Santa Cruz de la Sierra to Uyuni bus services, operated by Autotransportes Tupiza, depart from Santa Cruz de la Sierra station.

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The best way to get from Santa Cruz de la Sierra to Uyuni is to fly which takes 2 h 50 min and costs $120 - $300. Alternatively, you can bus, which costs $22 - $26 and takes 22 h.

Mode details

The quickest flight from Santa Cruz Airport to Uyuni Airport is the direct flight which takes 1 h 15 min.

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Santa Cruz de la Sierra to Uyuni bus services, operated by Expreso 11 de Julio, arrive at Uyuni station.

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Map of how to get from Santa Cruz de la Sierra to Uyuni.
Launch map view
  • Distance: 303 miles
  • Duration: 2 h 50 min

What companies run services between Santa Cruz de la Sierra, Bolivia and Uyuni, Potosí, Bolivia?

Amaszonas and Boliviana de Aviación fly from Santa Cruz de la Sierra to Uyuni twice daily. Alternatively, you can take a bus from Santa Cruz de la Sierra to Uyuni via Potosí and Potosi in around 22 h.

Airlines
Boliviana de Aviación
Website
boa.bo
Flights from Santa Cruz to Uyuni via La Paz
Ave. Duration
3 h 7 min
When
Every day
Estimated price
$110 - $350
Amaszonas
Website
amaszonas.com
Flights from Santa Cruz to Uyuni
Ave. Duration
1 h 15 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$110 - $900
Train operators
Empresa Ferroviaria Andina S.A
Phone
(+591-2) 2184555 / 4566
Website
fca.com.bo
Train from Oruro to Uyuní
Ave. Duration
7 h 20 min
Frequency
4 times a week
Estimated price
$4 - $19
Schedules at
fca.com.bo
Book at
ticketsbolivia.com.bo
Wara Wara del Sur - Popular
$4 - $6
Wara Wara del Sur - Salon
$7 - $9
Expreso del Sur - Salon
$9 - $11
Wara Wara del Sur - Ejecutivo
$15 - $19
Bus operators
Trans Carrasco
Phone
+591 60362456 Cochabamba / 4 4225457 Cochabamba / 71490343 Sucre
Email
jose_eddyporsiempre@hotmail.com
Website
facebook.com
Bus from Santa Cruz de la Sierra - Terminal Bimodal to Cochabamba
Ave. Duration
9 h
Frequency
Every 4 hours
Estimated price
$9 - $11
Schedules at
facebook.com
Cosmos
Phone
+(591) 2 2281938 / Potosí: +(591)2-6245831
Bus from Santa Cruz de la Sierra to Cochabamba
Ave. Duration
9 h
Frequency
5 times a day
Estimated price
$19
Schedules at
sites.google.com
Trans Llallagua
Phone
+(591)-79967601
Bus from Cochabamba to Provincia Arque
Ave. Duration
1 h 35 min
Frequency
Once daily
Estimated price
$33
Book at
andestransit.com
Autotransportes Tupiza
Phone
+591 68421233 Tupiza / 3 3311649 Santa Cruz / 2 6243044 Potosí
Website
facebook.com
Bus from Santa Cruz de la Sierra to Potosí
Ave. Duration
17 h
Frequency
Once daily
Estimated price
$13 - $17
Schedules at
facebook.com
Bus from Santa Cruz de la Sierra - Terminal Bimodal to Sucre
Ave. Duration
14 h
Frequency
Once daily
Estimated price
$10 - $13
Schedules at
facebook.com
Expreso 11 de Julio
Phone
+591 62459036
Website
facebook.com
Bus from Potosi to Uyuni
Ave. Duration
4 h
Frequency
Twice daily
Estimated price
$9
Schedules at
facebook.com
Book at
ticketsbolivia.com.bo
Trans Caminante SRL
Phone
+591 71162388 Santa Cruz / 4 6429385 Sucre
Website
facebook.com
Bus from Santa Cruz - Terminal Bimodal to Sucre
Ave. Duration
13 h 30 min
Frequency
Twice daily
Estimated price
$13
Schedules at
facebook.com
El Mexicano
Phone
+591 67640155
Website
facebook.com
Bus from Santa Cruz - Terminal Bimodal to Sucre
Ave. Duration
13 h
Frequency
Once daily
Estimated price
$15
Schedules at
facebook.com
Flota Bolivar
Phone
+591 2 2281973 La Paz / 4 4221819 Cochabamba / 3 3625458 Santa Cruz / 4 6453849 Sucre / 4 6830856 Yacuiba
Website
facebook.com
Bus from Santa Cruz to Sucre
Ave. Duration
13 h 30 min
Frequency
Once daily
Estimated price
$12 - $19
Schedules at
facebook.com
Trans 6 de Octubre

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More Questions & Answers

Yes, the driving distance between Santa Cruz de la Sierra to Uyuni is 847 km. It takes approximately 14 h 48 min to drive from Santa Cruz de la Sierra to Uyuni.

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Amaszonas and Boliviana de Aviación offer flights from Santa Cruz Airport to Uyuni Airport.

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There are 37+ hotels available in Uyuni. Prices start at $12 USD per night.

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The best way to get from Santa Cruz de la Sierra to Santa Cruz Airport is to line 135 bus which takes 28 min and costs $1.

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