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There are 6 ways to get from Santa Cruz de la Sierra to Uyuni by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  2 h 50 min

  1. Fly from Santa Cruz (VVI) to Uyuni (UYU) VVI - UYU

$120 - $293

Cheapest option

Bus via Aiquile  •  17 h 7 min

  1. Take the bus from Santa Cruz - Tercer Anillo to Aiquile
  2. Take the bus from Aiquile to Sucre
  3. Take the bus from Sucre to Potosí
  4. Take the bus from Potosi to Uyuni

$21 - $28

4 alternative options

Bus Autotransportes Tupiza  •  22 h

  1. Take the bus from Santa Cruz de la Sierra to Potosí
  2. Take the bus from Potosi to Uyuni

$22 - $26

Bus Trans Caminante SRL  •  22 h 30 min

  1. Take the bus from Santa Cruz - Terminal Bimodal to Sucre
  2. Take the bus from Sucre to Uyuni

$28 - $36

Bus, train  •  22 h 56 min

  1. Take the bus from Santa Cruz de la Sierra - Terminal Bimodal to Oruro Santa Cruz
  2. Take the train from Oruro to Uyuní Expreso del Sur / ...

$30 - $67

Drive  •  14 h 48 min

  1. Drive from Santa Cruz de la Sierra to Uyuni 529.6 miles

$40 - $60

Questions & Answers

The cheapest way to get from Santa Cruz de la Sierra to Uyuni is to bus which costs $20 - $28 and takes 17 h 7 min.

More details

The quickest way to get from Santa Cruz de la Sierra to Uyuni is to fly which costs $120 - $300 and takes 2 h 50 min.

More details

No, there is no direct bus from Santa Cruz de la Sierra to Uyuni. However, there are services departing from Santa Cruz - Tercer Anillo and arriving at Uyuni via Aiquile, Sucre and Potosi. The journey, including transfers, takes approximately 17 h 7 min.

More details

The distance between Santa Cruz de la Sierra and Uyuni is 485 km. The road distance is 847.4 km.

Get driving directions

The best way to get from Santa Cruz de la Sierra to Uyuni without a car is to bus which takes 17 h 7 min and costs $20 - $28.

More details

It takes approximately 2 h 50 min to get from Santa Cruz de la Sierra to Uyuni, including transfers.

More details

Santa Cruz de la Sierra to Uyuni bus services, operated by Transporte Señor de Burgos, depart from Santa Cruz - Tercer Anillo station.

More details

The best way to get from Santa Cruz de la Sierra to Uyuni is to fly which takes 2 h 50 min and costs $120 - $300. Alternatively, you can bus, which costs $20 - $28 and takes 17 h 7 min.

Mode details

The quickest flight from Santa Cruz Airport to Uyuni Airport is the direct flight which takes 1 h 15 min.

Search flights

Santa Cruz de la Sierra to Uyuni bus services, operated by Expreso 11 de Julio, arrive at Uyuni station.

More details

Map of how to get from Santa Cruz de la Sierra to Uyuni.
Launch map view
  • Distance: 303 miles
  • Duration: 2 h 50 min

What companies run services between Santa Cruz de la Sierra, Bolivia and Uyuni, Potosí, Bolivia?

Amaszonas and Boliviana de Aviación fly from Santa Cruz de la Sierra to Uyuni twice daily. Alternatively, you can take a bus from Santa Cruz de la Sierra to Uyuni via Aiquile, Aiquile, Sucre, and Potosi in around 17 h 7 min.

Airlines
Boliviana de Aviación
Website
boa.bo
Flights from Santa Cruz to Uyuni via La Paz
Ave. Duration
3 h 7 min
When
Every day
Estimated price
$110 - $350
Amaszonas
Website
amaszonas.com
Flights from Santa Cruz to Uyuni
Ave. Duration
1 h 15 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$110 - $900
Train operators
Empresa Ferroviaria Andina S.A
Phone
(+591-2) 2184555 / 4566
Website
fca.com.bo
Train from Oruro to Uyuní
Ave. Duration
6 h 50 min
Frequency
4 times a week
Estimated price
$4 - $19
Schedules at
ferroviaria-andina.com.bo
Book at
ticketsbolivia.com.bo
Wara Wara del Sur - Popular
$4 - $6
Wara Wara del Sur - Salon
$7 - $9
Expreso del Sur - Salon
$9 - $11
Wara Wara del Sur - Ejecutivo
$15 - $19
Bus operators
Transporte Señor de Burgos
Phone
+591 4 4303530 Cochabamba / 4 4342227 Mizque
Website
facebook.com
Bus from Santa Cruz - Tercer Anillo to Aiquile
Ave. Duration
6 h
Frequency
Once daily
Estimated price
$6
Schedules at
facebook.com
Trans Copacabana SA
Phone
Cochabamba: +(591)44591818, +(591)72244625
Email
info@transcopacabanasa.com.bo
Website
transcopacabanasa.com.bo
Bus from Aiquile to Sucre
Ave. Duration
1 h 30 min
Frequency
Twice daily
Estimated price
$4 - $7
Schedules at
transcopacabanasa.com.bo
Book at
ticketsbolivia.com.bo
3rd Class
$4 - $6
2nd Class
$5 - $7
Bus from Santa Cruz de la Sierra - Terminal Bimodal to Oruro
Ave. Duration
15 h
Frequency
Once daily
Estimated price
$11 - $30
Schedules at
transcopacabanasa.com.bo
Book at
ticketsbolivia.com.bo
3rd Class
$11 - $15
2nd Class
$16 - $22
Trans Emperador
Phone
+591 68660423
Website
facebook.com
Bus from Sucre to Potosí
Ave. Duration
3 h
Frequency
Every 3 hours
Schedules at
busesbolivia.wordpress.com
Trans 6 de Octubre
Phone
+591 79576765
Bus from Sucre to Potosí
Ave. Duration
3 h
Frequency
Every 4 hours
Estimated price
$4
Schedules at
facebook.com
Book at
ticketsbolivia.com.bo
Bus from Sucre to Uyuni
Ave. Duration
8 h
Frequency
Twice daily
Estimated price
$18
Schedules at
ticketsbolivia.com.bo
Book at
ticketsbolivia.com.bo
Transtin Dil Rey
Phone
+591 4 6452518
Website
facebook.com
Bus from Sucre to Potosí
Ave. Duration
3 h
Frequency
5 times a day
Estimated price
$6
Schedules at
facebook.com
Linea Sindical Flota Villa Imperial
Phone
+(591)-2-6243373
Website
facebook.com
Bus from Sucre to Potosí
Ave. Duration
3 h
Frequency
4 times a day
Estimated price
$3
Schedules at
potosy.com.bo
Expreso 11 de Julio
Phone
+591 62459036
Website
facebook.com
Bus from Potosi to Uyuni
Ave. Duration
4 h
Frequency
Twice daily
Estimated price
$9
Schedules at
facebook.com
Book at
ticketsbolivia.com.bo
Autotransportes Tupiza
Phone
+591 68421233 Tupiza / 3 3311649 Santa Cruz / 2 6243044 Potosí
Website
facebook.com
Bus from Santa Cruz de la Sierra to Potosí
Ave. Duration
17 h
Frequency
Once daily
Estimated price
$13 - $17
Schedules at
facebook.com
Bus from Santa Cruz de la Sierra - Terminal Bimodal to Sucre
Ave. Duration
14 h
Frequency
Once daily
Estimated price
$10 - $13
Schedules at
facebook.com
Trans Caminante SRL
Phone
+591 71162388 Santa Cruz / 4 6429385 Sucre
Website
facebook.com
Bus from Santa Cruz - Terminal Bimodal to Sucre
Ave. Duration
13 h 30 min
Frequency
Twice daily
Estimated price
$14
Schedules at
facebook.com
El Mexicano
Phone
+591 67640155
Website
facebook.com
Bus from Santa Cruz - Terminal Bimodal to Sucre
Ave. Duration
13 h
Frequency
Once daily
Estimated price
$15
Schedules at
facebook.com
Flota Bolivar
Phone
+591 2 2281973 La Paz / 4 4221819 Cochabamba / 3 3625458 Santa Cruz / 4 6453849 Sucre / 4 6830856 Yacuiba
Website
facebook.com
Bus from Santa Cruz to Sucre
Ave. Duration
13 h 30 min
Frequency
Once daily
Estimated price
$12 - $19
Schedules at
facebook.com
Todo Turismo
Phone
+(591) 2228 7038
Email
atencionalcliente@todoturismosrl.com
Website
todoturismosrl.com
Bus from Sucre Bus Terminal to Uyuni
Ave. Duration
12 h 30 min
Frequency
Once daily
Schedules at
todoturismosrl.com
Book at
todoturismosrl.com

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More Questions & Answers

Yes, the driving distance between Santa Cruz de la Sierra to Uyuni is 847 km. It takes approximately 14 h 48 min to drive from Santa Cruz de la Sierra to Uyuni.

Get driving directions

Amaszonas and Boliviana de Aviación offer flights from Santa Cruz Airport to Uyuni Airport.

Search flights

There are 36+ hotels available in Uyuni. Prices start at $15 USD per night.

More details

The best way to get from Santa Cruz de la Sierra to Santa Cruz Airport is to line 135 bus which takes 28 min and costs $1.

More details