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There are 5 ways to get from Santa Cruz de la Sierra to Rome by plane or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Rome  •  17h 50m

  1. Fly from Santa Cruz (VVI) to Rome (FCO) VVI - FCO

328€ - 836€

4 alternative options

Fly to Florence, train  •  22h 33m

  1. Fly from Santa Cruz (VVI) to Florence (FLR) VVI - FLR
  2. Take the train from Firenze S.M.N. to Roma Termini

459€ - 1178€

Fly to Naples, train  •  20h 44m

  1. Fly from Santa Cruz (VVI) to Naples (NAP) VVI - NAP
  2. Take the train from Napoli Centrale to Roma Termini

410€ - 1071€

Fly to Rome Ciampino  •  22h 32m

  1. Fly from Santa Cruz (VVI) to Rome Ciampino (CIA) VVI - CIA

364€ - 907€

Fly to Bologna, train  •  19h 50m

  1. Fly from Santa Cruz (VVI) to Bologna (BLQ) VVI - BLQ
  2. Take the train from Bologna Centrale to Roma Termini

389€ - 1017€

Coronavirus (COVID-19) in Italy

There is widespread community transmission globally.
Some travel restrictions are being lifted in Italy. For the latest travel status, please check the official page for Italy.

For travel planning advice, please refer to our Rome2rio Coronavirus information page .
For the latest travel status, we recommend checking the official page for Italy.

Coronavirus (COVID-19) Travel Advice

Some international borders began to reopen in Italy from June 3.

Official Coronavirus (COVID-19) Information for Italy

Some domestic travel restrictions began to ease in Italy from June 3.

Official Coronavirus (COVID-19) Information for Italy

International flights leaving Bolivia are suspended as part of the response to Coronavirus (COVID-19). Restrictions may also be in place for other modes of transport.

Official Coronavirus (COVID-19) Information for Bolivia

Last updated: August 5 | Data sourced from: ACAPS, OXFORD

Questions & Answers

The cheapest way to get from Santa Cruz de la Sierra to Rome is to fly which costs $380 - $1,000 and takes 17h 50m.

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The quickest way to get from Santa Cruz de la Sierra to Rome is to fly which costs $380 - $1,000 and takes 17h 50m.

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The distance between Santa Cruz de la Sierra and Rome is 10191 km.

It takes approximately 17h 50m to get from Santa Cruz de la Sierra to Rome, including transfers.

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There is no direct flight from Santa Cruz Airport to Rome Airport. The quickest flight takes 14h 40m and has one stopover.

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Rome is 6h ahead of Santa Cruz de la Sierra. It is currently 9:51 PM in Santa Cruz de la Sierra and 3:51 AM in Rome.

Iberia, Gol Transportes Aéreos, Vueling Airlines and three other airlines offer flights from Santa Cruz Airport to Rome Airport.

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There are 6480+ hotels available in Rome. Prices start at 87€ per night.

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The best way to get from Santa Cruz de la Sierra to Santa Cruz Airport is to line 135 bus which takes 28 min and costs $1.

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Map of how to get from Santa Cruz de la Sierra to Rome.
Launch map view
  • Distance: 10190.7 km
  • Duration: 17h 50m

What companies run services between Santa Cruz de la Sierra, Bolivia and Rome, Italy?

Air Europa, Boliviana de Aviación and four other airlines fly from Santa Cruz de la Sierra to Rome 3 times a day.

Airlines
Iberia
Website
iberia.com
Flights from Santa Cruz to Rome via Madrid
Ave. Duration
16h
When
Monday and Saturday
Estimated price
600€ - 1900€
Flights from Santa Cruz to Rome via Madrid, Barcelona
Ave. Duration
17h 15m
When
Monday and Saturday
Estimated price
600€ - 1900€
Flights from Santa Cruz to Florence via Madrid, Barcelona
Ave. Duration
19h 30m
When
Monday, Tuesday and Saturday
Estimated price
650€ - 1900€
Flights from Santa Cruz to Florence via Madrid, London Gatwick
Ave. Duration
20h 5m
When
Tuesday
Estimated price
480€ - 1200€
Flights from Santa Cruz to Florence via Sao Paulo, Madrid
Ave. Duration
21h 10m
When
Monday
Estimated price
550€ - 2000€
Flights from Santa Cruz to Naples via Madrid
Ave. Duration
16h 25m
When
Monday and Saturday
Estimated price
550€ - 1700€
Flights from Santa Cruz to Naples via Madrid, Barcelona
Ave. Duration
18h 45m
When
Monday, Tuesday and Saturday
Estimated price
500€ - 1500€
Flights from Santa Cruz to Bologna via Madrid
Ave. Duration
15h 45m
When
Monday, Tuesday and Saturday
Estimated price
500€ - 1600€
Alitalia
Website
alitalia.com
Flights from Santa Cruz to Rome via Sao Paulo
Ave. Duration
16h 42m
When
Monday, Wednesday, Friday and Saturday
Estimated price
350€ - 900€
Flights from Santa Cruz to Rome via Madrid
Ave. Duration
17h 15m
When
Monday and Saturday
Estimated price
600€ - 1900€
Flights from Santa Cruz to Florence via Sao Paulo, Rome
Ave. Duration
20h 10m
When
Monday, Wednesday, Friday and Saturday
Estimated price
500€ - 1300€
Flights from Santa Cruz to Florence via Madrid, Rome
Ave. Duration
20h
When
Monday and Saturday
Estimated price
850€ - 2800€
Vueling Airlines
Website
vueling.com
Flights from Santa Cruz to Florence via Madrid, Barcelona
Ave. Duration
19h 30m
When
Tuesday and Saturday
Estimated price
440€ - 1100€
Flights from Santa Cruz to Florence via Madrid, London Gatwick
Ave. Duration
20h 5m
When
Tuesday
Estimated price
480€ - 1200€
Flights from Santa Cruz to Florence via Madrid, Paris Orly
Ave. Duration
20h 45m
When
Tuesday and Saturday
Estimated price
470€ - 1200€
Flights from Santa Cruz to Naples via Madrid
Ave. Duration
16h 25m
When
Saturday
Estimated price
390€ - 1000€
Flights from Santa Cruz to Naples via Madrid, Barcelona
Ave. Duration
18h 45m
When
Tuesday and Saturday
Estimated price
390€ - 1000€
Air Europa
Website
aireuropa.com
Flights from Santa Cruz to Rome via Madrid
Ave. Duration
16h 23m
When
Monday, Tuesday and Saturday
Estimated price
410€ - 1200€
Flights from Santa Cruz to Rome via Madrid, Valencia
Ave. Duration
17h 10m
When
Tuesday and Saturday
Estimated price
320€ - 800€
Flights from Santa Cruz to Rome via Madrid, Malaga
Ave. Duration
17h 40m
When
Tuesday and Saturday
Estimated price
330€ - 850€
Lufthansa
Website
lufthansa.com
Flights from Santa Cruz to Florence via Madrid, Munich
Ave. Duration
17h 55m
When
Tuesday and Saturday
Estimated price
470€ - 1200€
Flights from Santa Cruz to Florence via Sao Paulo, Munich
Ave. Duration
18h 15m
When
Friday
Estimated price
650€ - 2600€
Flights from Santa Cruz to Naples via Sao Paulo, Munich
Ave. Duration
19h 15m
When
Friday
Estimated price
550€ - 2300€
Flights from Santa Cruz to Bologna via Madrid, Munich
Ave. Duration
16h 45m
When
Tuesday and Saturday
Estimated price
380€ - 950€
Air Leisure
Website
air-leisure.com
Flights from Santa Cruz to Rome Ciampino via Madrid
Ave. Duration
20h 10m
When
Tuesday and Saturday
Estimated price
360€ - 900€
Flights from Santa Cruz to Rome Ciampino via Madrid, Palma Mallorca
Ave. Duration
19h 10m
When
Saturday
Estimated price
360€ - 900€
Flights from Santa Cruz to Rome Ciampino via Sao Paulo, Lisbon
Ave. Duration
28h 30m
When
Monday
Estimated price
340€ - 1400€
Flights from Santa Cruz to Bologna via Madrid, Valencia
Ave. Duration
18h 45m
When
Saturday
Estimated price
370€ - 900€
KLM
Website
klm.com
Flights from Santa Cruz to Florence via Madrid, Amsterdam Schiphol
Ave. Duration
19h 45m
When
Tuesday and Saturday
Estimated price
490€ - 1200€
Flights from Santa Cruz to Florence via Madrid, Paris CDG
Ave. Duration
19h 50m
When
Tuesday
Estimated price
470€ - 1200€
Flights from Santa Cruz to Florence via Sao Paulo, Paris CDG
Ave. Duration
21h 20m
When
Monday and Saturday
Estimated price
750€ - 3300€
Air Dolomiti
Website
airdolomiti.it
Flights from Santa Cruz to Florence via Madrid, Munich
Ave. Duration
17h 55m
When
Tuesday and Saturday
Estimated price
470€ - 1200€
Flights from Santa Cruz to Bologna via Madrid, Munich
Ave. Duration
16h 45m
When
Tuesday and Saturday
Estimated price
380€ - 950€
Air France
Website
airfrance.com
Flights from Santa Cruz to Florence via Madrid, Paris CDG
Ave. Duration
19h 50m
When
Tuesday
Estimated price
470€ - 1200€
Flights from Santa Cruz to Florence via Sao Paulo, Paris CDG
Ave. Duration
21h 20m
When
Monday and Saturday
Estimated price
750€ - 3300€
Boliviana de Aviación
Website
boa.bo
Flights from Santa Cruz to Rome via Madrid
Ave. Duration
16h
When
Monday and Saturday
Estimated price
600€ - 1900€
Swiss
Website
swiss.com
Flights from Santa Cruz to Florence via Sao Paulo, Zurich
Ave. Duration
18h 30m
When
Friday
Estimated price
650€ - 1800€
Wizz Air
Website
wizzair.com
Flights from Santa Cruz to Rome Ciampino via Madrid, Craiova
Ave. Duration
28h 45m
When
Tuesday
Estimated price
410€ - 1100€
Ryanair
Website
ryanair.com
Flights from Santa Cruz to Bologna via Madrid
Ave. Duration
14h 5m
When
Tuesday
Estimated price
360€ - 900€
Train operators
Trenitalia Frecce

Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.M.N. to Roma Termini
Ave. Duration
1h 35m
Frequency
Every 30 minutes
Estimated price
21€ - 75€
Website
Trenitalia Frecce
Super Economy
21€ - 29€
Base Standard
40€ - 55€
Base Premium
50€ - 75€
Train from Napoli Centrale to Roma Termini
Ave. Duration
1h 16m
Frequency
Hourly
Estimated price
18€ - 65€
Website
Trenitalia Frecce
Super Economy
18€ - 25€
Base Standard
35€ - 50€
Base Premium
45€ - 65€
Train from Bologna Centrale to Roma Termini
Ave. Duration
2h 24m
Frequency
Every 30 minutes
Estimated price
27€ - 90€
Website
Trenitalia Frecce
Super Economy
27€ - 40€
Base Standard
50€ - 70€
Base Premium
60€ - 90€
ItaloTreno

Private train company Italotreno operates high-speed trains in Italy on the same tracks as Trenitalia. The routes service 21 stations across the country, including popular routes Milan-Florence, Rome-Venice and Bologna-Naples. Choose from four classes of service, all with free Wi-Fi: Smart, Comfort, Prima and Club Executive. Italo also operates Italobus – an integrated train-bus service that takes passengers from the main train stations to other Italian cities.

Contact Details
Phone
+39 060708
Website
italotreno.it
Train from Firenze Santa Maria Novella to Roma Termini
Ave. Duration
1h 37m
Frequency
Hourly
Estimated price
19€ - 55€
Website
Italo Treno
Smart Economy
21€ - 30€
Smart Low Cost
19€ - 27€
Smart Flex
40€ - 55€
Train from Napoli Centrale Station to Roma Termini
Ave. Duration
1h 13m
Frequency
Hourly
Estimated price
17€ - 50€
Website
Italo Treno
Smart Economy
19€ - 27€
Smart Low Cost
17€ - 24€
Smart Flex
35€ - 50€
Trenitalia Intercity

Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.M.N. to Roma Termini
Ave. Duration
2h 35m
Frequency
6 times a week
Estimated price
16€ - 24€
Website
Trenitalia Intercity
2nd Class
16€ - 24€
Train from Napoli Centrale to Roma Termini
Ave. Duration
2h 3m
Frequency
Every 4 hours
Estimated price
14€ - 20€
Website
Trenitalia Intercity
2nd Class
14€ - 20€
Train from Bologna Centrale to Roma Termini
Ave. Duration
4h 17m
Frequency
Twice daily
Estimated price
22€ - 35€
Website
Trenitalia Intercity
2nd Class
22€ - 35€
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Napoli Centrale to Roma Termini
Ave. Duration
2h 43m
Frequency
Every 4 hours
Estimated price
14€ - 29€
Website
Trenitalia
1st Class
26€ - 29€

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.