There are 5 ways to get from Santa Clarita to San Diego by bus, train, night bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Amtrak Thruway, bus  •  4 h 38 min

  1. Take the Amtrak Thruway from Santa Clarita, CA to Los Angeles, CA 5818
  2. Take the bus from Los Angeles, Ca to San Diego, Ca 9465

$18 - $46

4 alternative options

Train  •  4 h 54 min

  1. Take the train from Newhall station to L. A. Union Station station Antelope Valley Line
  2. Take the train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak Pacific Surfliner

$37 - $84

Train, night bus  •  4 h 46 min

  1. Take the train from Newhall station to L. A. Union Station station Antelope Valley Line
  2. Take the night bus from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak Amtrak Thruway Connecting Service

Drive  •  2 h 41 min

  1. Drive from Santa Clarita to San Diego 152.8 miles

$15 - $22

Train, fly  •  4 h 38 min

  1. Take the train from Newhall station to L. A. Union Station station
  2. Fly from Los Angeles (LAX) to San Diego (SAN) LAX - SAN

$115 - $360

Questions & Answers

The cheapest way to get from Santa Clarita to San Diego is to drive which costs $15 - $22 and takes 2 h 41 min.

More details

The quickest way to get from Santa Clarita to San Diego is to drive which costs $15 - $22 and takes 2 h 41 min.

More details

The distance between Santa Clarita and San Diego is 141 miles. The road distance is 152.8 miles.

Get driving directions

It takes approximately 4 h 38 min to get from Santa Clarita to San Diego, including transfers.

More details

No, there is no direct bus from Santa Clarita to San Diego. However, there are services departing from Santa Clarita, CA and arriving at San Diego, Ca via Patsaouras Transit Plaza, 6th / Broadway and Los Angeles, Ca. The journey, including transfers, takes approximately 4 h 38 min.

More details

No, there is no direct train from Santa Clarita station to San Diego. However, there are services departing from Newhall station and arriving at San Diego Santa Fe Depot Amtrak via Los Angeles Union Station Amtrak. The journey, including transfers, takes approximately 4 h 54 min.

More details

The nearest airport to San Diego is San Diego (SAN) Airport which is 2.4 miles away. Other nearby airports include Tijuana (TIJ) (16 miles), Santa Ana (SNA) (78.4 miles), Los Angeles (LAX) (111.9 miles) and Burbank (BUR) (123.9 miles).

Search flights

Santa Clarita to San Diego bus services, operated by Amtrak, arrive at L. A. Union Station station.

More details

Map of how to get from Santa Clarita to San Diego.
Launch map view
  • Distance: 141.3 miles
  • Duration: 4 h 38 min

What companies run services between Santa Clarita, CA, USA and San Diego, CA, USA?

You can take a bus from Santa Clarita to San Diego via Los Angeles, CA, Patsaouras Transit Plaza, Spring & 7th, 6th / Broadway, 7th / Decatur, and Los Angeles, Ca in around 4 h 38 min. Alternatively, you can take a train from Santa Clarita to San Diego via L. A. Union Station station and Los Angeles Union Station Amtrak in around 4 h 54 min.

Airlines
Delta
Website
delta.com
Flights from Los Angeles to San Diego
Ave. Duration
59 min
When
Every day
Estimated price
$140 - $600
American Airlines
Website
aa.com
Flights from Los Angeles to San Diego
Ave. Duration
52 min
When
Every day
Estimated price
$110 - $600
United Airlines
Website
united.com
Flights from Los Angeles to San Diego
Ave. Duration
57 min
When
Every day
Estimated price
$110 - $650
Train operators
Metrolink Trains
Phone
(800) 371-LINK (5465)
Website
metrolinktrains.com
Train from Newhall station to L. A. Union Station station
Ave. Duration
57 min
Frequency
Every 2 hours
Estimated price
$7 - $10
Schedules at
metrolinktrains.com
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak
Ave. Duration
2 h 53 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Bus operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Santa Clarita, CA to Los Angeles, CA
Ave. Duration
1 h 5 min
Frequency
Once daily
Website
amtrak.com
Night bus from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak
Ave. Duration
2 h 45 min
Frequency
Once daily
Website
amtrak.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Los Angeles, Ca to San Diego, Ca
Ave. Duration
2 h 20 min
Frequency
Hourly
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40

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