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There are 6 ways to get from Santa Clara to Santiago de Cuba by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  11h

  1. Take the bus from Santa Clara to Santiago de Cuba Via Santiago de Cuba

$29 - $45

Cheapest option

Train  •  11h 1m

  1. Take the train from Santa Clara to Santiago de Cuba

$25 - $40

4 alternative options

Drive  •  8h 48m

  1. Drive from Santa Clara to Santiago de Cuba 374.7 miles

Fly Santa Clara to Holguin, train  •  12h 10m

  1. Fly from Santa Clara (SNU) to Holguin (HOG) SNU - HOG
  2. Take the train from Cacocum to Santiago de Cuba

$486 - $2,435

Fly Santa Clara to Camaguey, train  •  18h 7m

  1. Fly from Santa Clara (SNU) to Camaguey (CMW) SNU - CMW
  2. Take the train from Camaguey to Santiago de Cuba

$307 - $1,356

Train to Havana, fly to Santiago  •  11h 37m

  1. Take the train from Santa Clara to Havana - La Coubre
  2. Fly from Havana (HAV) to Santiago (SCU) HAV - SCU

$135 - $361

Questions & Answers

The cheapest way to get from Santa Clara to Santiago de Cuba is to train which costs $25 - $40 and takes 11h 1m.

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The quickest way to get from Santa Clara to Santiago de Cuba is to bus which costs $29 - $45 and takes 11h.

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Yes, there is a direct bus departing from Santa Clara and arriving at Santiago de Cuba. Services depart three times a day, and operate every day. The journey takes approximately 11h.

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Yes, there is a direct train departing from Santa Clara and arriving at Santiago de Cuba. Services depart hourly. The journey takes approximately 11h 1m.

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The distance between Santa Clara and Santiago de Cuba is 504 km. The road distance is 599.5 km.

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The best way to get from Santa Clara to Santiago de Cuba without a car is to bus which takes 11h and costs $29 - $45.

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The bus from Santa Clara to Santiago de Cuba takes 11h including transfers and departs three times a day.

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Santa Clara to Santiago de Cuba bus services, operated by Viazul, depart from Santa Clara station.

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Santa Clara to Santiago de Cuba train services, operated by Ferrocarriles de Cuba, depart from Santa Clara station.

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The best way to get from Santa Clara to Santiago de Cuba is to bus which takes 11h and costs $29 - $45. Alternatively, you can train, which costs $25 - $40 and takes 11h 1m.

Mode details

Map of how to get from Santa Clara to Santiago de Cuba.
Launch map view
  • Distance: 315.2 miles
  • Duration: 11h

What companies run services between Santa Clara, Cuba and Santiago de Cuba?

Viazul operates a bus from Santa Clara to Santiago de Cuba 3 times a day. Tickets cost $29 - $45 and the journey takes 11h. Alternatively, Ferrocarriles de Cuba operates a train from Santa Clara to Santiago de Cuba on demand. Tickets cost $25 - $40 and the journey takes 11h 1m.

Airlines
Cubana de Aviación
Website
cubana.cu
Flights from Santa Clara to Camaguey via Panama City, Havana
Ave. Duration
10h 59m
When
Tuesday
Estimated price
$3,100 - $8,000
Flights from Havana to Santiago
Ave. Duration
1h 46m
When
Every day
Estimated price
$120 - $550
Sunwing Airlines
Website
sunwing.ca
Flights from Santa Clara to Holguin via Montreal
Ave. Duration
8h 50m
When
Monday
Estimated price
$1,000 - $3,400
Flights from Santa Clara to Holguin via Toronto
Ave. Duration
11h 45m
When
Tuesday and Friday
Estimated price
$950 - $3,100
Flights from Santa Clara to Camaguey via Toronto
Ave. Duration
14h
When
Tuesday
Estimated price
$950 - $3,100
Flights from Santa Clara to Camaguey via Montreal
Ave. Duration
18h 5m
When
Tuesday
Estimated price
$1,000 - $3,400
Air Transat
Website
airtransat.com
Flights from Santa Clara to Holguin via Montreal
Ave. Duration
9h 20m
When
Friday
Estimated price
$850 - $6,000
Flights from Santa Clara to Holguin via Toronto
Ave. Duration
9h 35m
When
Saturday
Estimated price
$800 - $5,500
Flights from Santa Clara to Holguin via Halifax
Ave. Duration
9h 50m
When
Friday
Estimated price
$900 - $6,500
JetBlue Airways
Website
jetblue.com
Flights from Santa Clara to Camaguey via Fort Lauderdale
Ave. Duration
19h 30m
When
Every day
Estimated price
$270 - $1,300
American Airlines
Website
aa.com
Flights from Santa Clara to Camaguey via Miami
Ave. Duration
22h 20m
When
Every day
Estimated price
$300 - $1,500
Fly Always N.V
Website
flyallways.com
Flights from Havana to Santiago
Ave. Duration
1h 20m
When
Tuesday
Estimated price
$60 - $400
Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Santa Clara to Santiago de Cuba
Ave. Duration
11h 1m
Frequency
On demand
Estimated price
$25 - $40
Schedules at
seat61.com
Train from Cacocum to Santiago de Cuba
Ave. Duration
2h 35m
Frequency
On demand
Estimated price
$7 - $11
Schedules at
seat61.com
Train from Camaguey to Santiago de Cuba
Ave. Duration
6h 15m
Frequency
On demand
Estimated price
$16 - $30
Schedules at
seat61.com
Train from Santa Clara to Havana - La Coubre
Ave. Duration
7h 30m
Frequency
On demand
Estimated price
$6 - $10
Schedules at
seat61.com
Bus operators

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More Questions & Answers

There is no direct flight from Santa Clara Airport to Holguin Airport. The quickest flight takes 8h 55m and has one stopover.

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Santa Clara to Santiago de Cuba bus services, operated by Viazul, arrive at Santiago de Cuba station.

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Santa Clara to Santiago de Cuba train services, operated by Ferrocarriles de Cuba, arrive at Santiago de Cuba station.

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Yes, the driving distance between Santa Clara to Santiago de Cuba is 599 km. It takes approximately 8h 48m to drive from Santa Clara to Santiago de Cuba.

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Air Canada, Air Transat and Sunwing Airlines offer flights from Santa Clara Airport to Holguin Airport.

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There are 127+ hotels available in Santiago de Cuba. Prices start at $25 USD per night.

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The best way to get from Santa Clara to Santa Clara Airport is to taxi which takes 13m and costs $12 - $15.

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