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How to get fromSanta Ana to Tucsonby plane, train (Amtrak), bus, car, or train

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There are 7 ways to get from Santa Ana to Tucson by plane, train (Amtrak), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Tucson

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Tucson (TUS)plane plane SNA - TUS
    2h 40m
    $103–483

  2. Bus

    cheapest
    1. Take the bus from Santa Ana to Tucsonbus bus Cbx
    13h 32m
    $80–111

  3. Train (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to Tucson Amtrak Stationtrain train Texas Eagle / ...
    11h 31m
    $161–353

  4. Bus via Los Angeles

    1. Take the bus from Santa Ana to Huntington Parkbus bus 2
    2. Take the bus from Huntington Park to Tucsonbus bus Huntington Park / ...
    12h 5m
    $83–124

  5. Drive 471 mi

    1. Drive from Santa Ana to Tucsoncar car 471 mi
    7h 37m
    $86–125

  6. Fly John Wayne Airport Orange County to Phoenix, bus

    1. Fly from John Wayne Airport Orange County (SNA) to Phoenix (PHX)plane plane SNA - PHX
    2. Take the bus from Sky Harbor International Airport to University of Phoenixbus bus
    4h 7m
    $143–718

  7. Train to Los Angeles International Airport, fly to Tucson

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Tucson (TUS)plane plane LAX - TUS
    5h 17m
    $518–1,136

Santa Ana to Tucson by train (Amtrak)

Calendar6Weekly Trains
Duration11h 31mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Tucson.ExpandLaunch map view
  • Distance: 430.3 mi
  • Duration: 2h 40m

What companies run services between Santa Ana, CA, USA and Tucson, AZ, USA?

Alaska Airlines, Inc., Southwest Airlines, and American Airlines fly from John Wayne Airport Orange County (SNA) to Tucson (TUS) 4 times a day. Alternatively, you can take a train from Santa Ana to Tucson Amtrak Station via Los Angeles in around 11h 31m.

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