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How to get fromSanta Ana to Pittsburghby plane, train (Amtrak), bus (Greyhound), car, train, or bus

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There are 10 ways to get from Santa Ana to Pittsburgh by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Pittsburgh International Airport

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Pittsburgh International Airport (PIT)plane plane SNA - PIT
    9h 16m
    $182–802

  2. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    2d 6h
    $1,467–2,319

  3. Bus (Greyhound)

    1. Take the bus from Santa Ana to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Pittsburgh Intermodal Stationbus bus
    2d 9h
    $449–732

  4. Drive  2,404.1 mi

    1. Drive from Santa Ana to Pittsburghcar car 2,404.1 mi
    38h 53m
    $397–574

  5. Train to Los Angeles International Airport, fly to Pittsburgh International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Pittsburgh International Airport (PIT)plane plane LAX - PIT
    9h 1m
    $236–472

  6. Train to San Diego International Airport, fly to Pittsburgh International Airport

    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Pittsburgh International Airport (PIT)plane plane SAN - PIT
    9h 11m
    $189–725

  7. Fly Long Beach Airport to Pittsburgh International Airport

    1. Fly from Long Beach Airport (LGB) to Pittsburgh International Airport (PIT)plane plane LGB - PIT
    11h 35m
    $290–1,214

  8. Train, train to Ontario International Airport, fly to Pittsburgh International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Ontario Amtraktrain train
    3. Fly from Ontario International Airport (ONT) to Pittsburgh International Airport (PIT)plane plane ONT - PIT
    11h 56m
    $231–916

  9. Train to Los Angeles International Airport, fly to Cleveland-Hopkins International Airport, train

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Cleveland-Hopkins International Airport (CLE)plane plane LAX - CLE
    3. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train
    12h 29m
    $254–485

  10. Train, bus

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the bus from Chicago to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    2d 8h
    $1,294–2,042

Santa Ana to Pittsburgh by train (Amtrak)

Calendar7Weekly Trains
Duration2d 6hAverage Duration
Ticket$1,467Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santa Ana to Pittsburgh.ExpandLaunch map view
  • Distance: 2,139.7 mi
  • Duration: 9h 16m

What companies run services between Santa Ana, CA, USA and Pittsburgh, PA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from John Wayne Airport Orange County (SNA) to Pittsburgh International Airport (PIT) every 2 hours. Alternatively, you can take a train from Santa Ana to Pittsburgh Amtrak Station via Fullerton Amtrak Station and Chicago Union Station in around 2d 6h.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Need to know: Greyhound

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