There are 7 ways to get from Santa Ana to Iowa by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly John Wayne Airport Orange County to Des Moines
best- Fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM)plane SNA - DSM
3h 37m$144–543Train to Los Angeles International Airport, fly to Des Moines
cheapest- Take the train from Santa Ana to L.A. Union Stationtrain
- Fly from Los Angeles International Airport (LAX) to Des Moines (DSM)plane LAX - DSM
6h 12m$116–436Bus (Greyhound)
- Take the bus from Santa Ana Bus Stop to Las Vegas Bus Terminalbus
- Take the bus from Las Vegas Bus Terminal to Denver Union Stationbus
- Take the bus from Denver Union Station to Des Moinesbus
36h 45m$187–406Train, bus
- Take the train from Fullerton Amtrak Station to Kansas Citytrain Southwest Chief
- Take the bus from Kansas City to Des Moinesbus Jefferson 802 / ...
40h 38m$193–430Drive 1,679.8 mi
- Drive from Santa Ana to Des Moinescar 1,679.8 mi
26h 1m$307–443Fly John Wayne Airport Orange County to Omaha
- Fly from John Wayne Airport Orange County (SNA) to Omaha (OMA)plane SNA - OMA
5h 8m$262–1,162Train to Los Angeles International Airport, fly to Omaha
- Take the train from Santa Ana to L.A. Union Stationtrain
- Fly from Los Angeles International Airport (LAX) to Omaha (OMA)plane LAX - OMA
6h 5m$214–905
John Wayne Airport Orange County (SNA) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Santa Ana to Iowa is to bus which costs $180 - $410 and takes 36h 45m.
The fastest way to get from Santa Ana to Iowa is to fly which takes 3h 37m and costs $140 - $550.
The distance between Santa Ana and Iowa is 1446 miles. The road distance is 1689.6 miles.
The best way to get from Santa Ana to Iowa without a car is to bus which takes 36h 45m and costs $180 - $410.
It takes approximately 3h 37m to get from Santa Ana to Iowa, including transfers.
The best way to get from Santa Ana to Iowa is to fly which takes 3h 37m and costs $140 - $550. Alternatively, you can bus, which costs $180 - $410 and takes 36h 45m.
Iowa is 2h ahead of Santa Ana. It is currently 5:03 AM in Santa Ana and 7:03 AM in Iowa.
Yes, the driving distance between Santa Ana to Iowa is 1690 miles. It takes approximately 26h 1m to drive from Santa Ana to Iowa.
There are 180+ hotels available in Iowa.
What companies run services between Santa Ana, CA, USA and Iowa, USA?
Allegiant Air, American Airlines, and three other airlines fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Santa Ana Bus Stop to Des Moines via Las Vegas Bus Terminal, Denver Union Station, and Des Moines in around 36h 45m.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Des Moines via Las Vegas
- Ave. Duration
- 5h 7m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–490
Flights from John Wayne Airport Orange County to Des Moines via Phoenix
- Ave. Duration
- 6h 50m
- When
- Saturday
- Estimated price
- $100–500
Flights from John Wayne Airport Orange County to Omaha via Denver
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $210–1,100
Flights from John Wayne Airport Orange County to Omaha via Phoenix
- Ave. Duration
- 5h 12m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $220–1,100
Flights from John Wayne Airport Orange County to Omaha via Las Vegas
- Ave. Duration
- 5h 6m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $210–1,100
Flights from John Wayne Airport Orange County to Omaha via Dallas
- Ave. Duration
- 6h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $270–1,300
Flights from Los Angeles International Airport to Omaha via Las Vegas
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $170–850
Flights from Los Angeles International Airport to Omaha via Phoenix
- Ave. Duration
- 5h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $180–850
Flights from Los Angeles International Airport to Omaha via Denver
- Ave. Duration
- 5h 12m
- When
- Monday, Thursday, and Friday
- Estimated price
- $170–850
Flights from Los Angeles International Airport to Des Moines via Phoenix
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- $85–400
Flights from Los Angeles International Airport to Des Moines via Las Vegas
- Ave. Duration
- 4h 55m
- When
- Monday
- Estimated price
- $80–400
Flights from Los Angeles International Airport to Des Moines via Denver
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $80–400
- Website
- aa.com
Flights from John Wayne Airport Orange County to Des Moines via Phoenix
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $100–500
Flights from John Wayne Airport Orange County to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $120–600
Flights from John Wayne Airport Orange County to Omaha via Phoenix
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $220–1,100
Flights from John Wayne Airport Orange County to Omaha via Dallas/Ft.Worth
- Ave. Duration
- 5h 45m
- When
- Thursday and Friday
- Estimated price
- $270–1,300
Flights from Los Angeles International Airport to Omaha
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- $170–850
Flights from Los Angeles International Airport to Omaha via Phoenix
- Ave. Duration
- 5h 11m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $180–850
Flights from Los Angeles International Airport to Des Moines
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $80–390
Flights from Los Angeles International Airport to Des Moines via Phoenix
- Ave. Duration
- 5h 15m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $85–400
Flights from Los Angeles International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $100–450
- Website
- united.com
Flights from John Wayne Airport Orange County to Des Moines via Denver
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $100–490
Flights from John Wayne Airport Orange County to Omaha via Denver
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Los Angeles International Airport to Omaha via Denver
- Ave. Duration
- 5h 3m
- When
- Thursday and Friday
- Estimated price
- $170–850
Flights from Los Angeles International Airport to Des Moines via Denver
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $80–400
- Website
- delta.com
Flights from John Wayne Airport Orange County to Des Moines via Minneapolis
- Ave. Duration
- 6h 7m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–550
Flights from John Wayne Airport Orange County to Omaha via Salt Lake City
- Ave. Duration
- 5h 17m
- When
- Thursday and Friday
- Estimated price
- $230–1,100
Flights from Los Angeles International Airport to Omaha via Salt Lake City
- Ave. Duration
- 5h 15m
- When
- Thursday and Friday
- Estimated price
- $180–900
- Website
- allegiantair.com
Flights from John Wayne Airport Orange County to Des Moines
- Ave. Duration
- 3h 22m
- When
- Monday, Friday, and Sunday
- Estimated price
- $100–490
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fullerton Amtrak Station to Kansas City
- Ave. Duration
- 34h 31m
- Frequency
- Once daily
- Estimated price
- $160–320
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from Santa Ana to L.A. Union Station
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $8–12
- Website
- https://metrolinktrains.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Santa Ana Bus Stop to Las Vegas Bus Terminal
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Las Vegas Bus Terminal to Denver Union Station
- Ave. Duration
- 16h 5m
- Frequency
- Once daily
- Estimated price
- $70–160
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Des Moines
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide













