Rome2Rio

How to get fromSanta Ana to Iowaby plane, bus (Greyhound), train, bus, or car

Find Transport to Iowa

See all options

There are 5 ways to get from Santa Ana to Iowa by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM)plane plane SNA - DSM
    3h 35m
    $166–436

  2. Bus (Greyhound)

    1. Take the bus from Santa Ana Bus Stop to Las Vegas Bus Terminalbus bus
    2. Take the bus from Las Vegas Bus Terminal to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Des Moinesbus bus
    36h 45m
    $318–483

  3. Train, bus

    1. Take the train from Fullerton Amtrak Station to Kansas Citytrain train Southwest Chief
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson Lines 804 / ...
    40h 58m
    $1,007–1,584

  4. Drive  1,679.8 mi

    1. Drive from Santa Ana to Des Moinescar car 1,679.8 mi
    26h 2m
    $288–415

  5. Fly to Omaha

    1. Fly from John Wayne Airport Orange County (SNA) to Omaha (OMA)plane plane SNA - OMA
    5h 3m
    $213–613

Santa Ana to Iowa by train, foot, and bus

Calendar7Weekly Services
Duration40h 58mAverage Duration
Ticket$1,007Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Santa Ana to Iowa.ExpandLaunch map view
  • Distance: 1,437.9 mi
  • Duration: 3h 35m

What companies run services between Santa Ana, CA, USA and Iowa, USA?

Allegiant Air, Southwest Airlines, and four other airlines fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Santa Ana Bus Stop to Des Moines via Las Vegas Bus Terminal, Denver Union Station, and Des Moines in around 36h 45m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There