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How to get fromSanta Ana to Iowaby plane, bus (Greyhound), train, bus or car

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There are 7 ways to get from Santa Ana to Iowa by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Des Moines

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM)planeSNA - DSM
    3h 36m
    $254–1,003

  2. Train to Los Angeles International Airport, fly to Omaha

    cheapest
    1. Take the train from Santa Ana to L.A. Union Stationtrain
    2. Fly from Los Angeles International Airport (LAX) to Omaha (OMA)planeLAX - OMA
    6h 1m
    $184–704

  3. Bus

    1. Take the bus from Santa Ana Bus Stop to Las Vegas BusTerminalbus
    2. Take the bus from Las Vegas BusTerminal to Denver Union Stationbus
    3. Take the bus from Denver to Des Moinesbus
    35h 37m
    $221–442

  4. Train, bus

    1. Take the train from Fullerton Amtrak Station to Kansas CitytrainSouthwest Chief
    2. Take the bus from Kansas City to Des MoinesbusJefferson 802 / ...
    40h 35m
    $221–579

  5. Drive 1,679.8 mi

    1. Drive from Santa Ana to Des Moinescar1,679.8 mi
    25h 54m
    $307–443

  6. Fly John Wayne Airport Orange County to Omaha

    1. Fly from John Wayne Airport Orange County (SNA) to Omaha (OMA)planeSNA - OMA
    4h 58m
    $232–912

  7. Train to Los Angeles International Airport, fly to Des Moines

    1. Take the train from Santa Ana to L.A. Union Stationtrain
    2. Fly from Los Angeles International Airport (LAX) to Des Moines (DSM)planeLAX - DSM
    6h 17m
    $196–795

Santa Ana to Iowa by bus and foot

Calendar7Weekly Services
Duration35h 37mAverage Duration
Ticket$221Cheapest Price
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Questions & Answers

What companies run services between Santa Ana, CA, USA and Iowa, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Santa Ana Bus Stop to Des Moines via Las Vegas BusTerminal, Denver Union Station, and Denver in around 35h 37m.

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