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How to get fromSanta Ana to Esquipulasby train, plane, bus, taxi, or car

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There are 10 ways to get from Santa Ana to Esquipulas by train, plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Los Angeles International Airport, fly to Cuscatlán International Airport, bus

    best
    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Cuscatlán International Airport (SAL)plane plane LAX - SAL
    3. Take the bus from San Salvador Airport to San Salvadorbus bus
    4. Take the bus from San Salvador to San Ignaciobus bus
    12h 23m
    $352–2,150
  2. Fly John Wayne Airport Orange County to La Aurora International Airport, bus

    cheapest
    1. Fly from John Wayne Airport Orange County (SNA) to La Aurora International Airport (GUA)plane plane SNA - GUA
    2. Take the bus from Guatemala to Esquipulasbus bus
    15h 36m
    $155–634
  3. Train, bus, taxi

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to San Marcos Amtraktrain train
    3. Take the bus from San Marcos to Terminal Central de Autobuses del Nortebus bus
    4. Take the bus from Terminal Central de Autobuses del Norte to Huixtla ADObus bus
    5. Take the taxi from Huixtla to La Mesillataxi taxi
    6. Take the bus from La Mesilla to Calle Rooselvetbus bus
    7. Take the bus from Terminal de buses Oriente to San Luis Jilotepequebus bus
    8. Take the taxi from San Luis Jilotepeque to Esquipulastaxi taxi
    3d 16h
  4. Drive  4,367.5 km

    1. Drive from Santa Ana to Esquipulascar car 4,367.5 km
    2d 6h
    $456–659
  5. Train to Los Angeles International Airport, fly to La Aurora International Airport, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to La Aurora International Airport (GUA)plane plane LAX - GUA
    3. Take the bus from Guatemala to Esquipulasbus bus
    13h 3m
    $209–624
  6. Fly John Wayne Airport Orange County to Cuscatlán International Airport, bus

    1. Fly from John Wayne Airport Orange County (SNA) to Cuscatlán International Airport (SAL)plane plane SNA - SAL
    2. Take the bus from San Salvador Airport to San Salvadorbus bus
    3. Take the bus from San Salvador to San Ignaciobus bus
    13h 26m
    $158–660
  7. Train, train to Ontario International Airport, fly to Cuscatlán International Airport, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Ontario Amtraktrain train
    3. Fly from Ontario International Airport (ONT) to Cuscatlán International Airport (SAL)plane plane ONT - SAL
    4. Take the bus from San Salvador Airport to San Salvadorbus bus
    5. Take the bus from San Salvador to San Ignaciobus bus
    13h 34m
    $207–774
  8. Train, train to Ontario International Airport, fly to La Aurora International Airport, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Ontario Amtraktrain train
    3. Fly from Ontario International Airport (ONT) to La Aurora International Airport (GUA)plane plane ONT - GUA
    4. Take the bus from Guatemala to Esquipulasbus bus
    17h 20m
    $204–748
  9. Bus to Tijuana International Airport, fly to Tapachula International Airport, drive, bus

    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Tapachula International Airport (TAP)plane plane TIJ - TAP
    3. Drive from Tapachula International Airport (TAP) to San Pablocar car
    4. Take the bus from San Pablo to Transportes Fuente del Nortebus bus
    5. Take the bus from Guatemala to Esquipulasbus bus
    16h 41m
    $300–766
  10. Train, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the bus from Los Angeles to Guatemala Citybus bus
    3. Take the bus from Guatemala to Esquipulasbus bus
    3d 17h
    $314–446

Los Angeles International Airport (LAX) to Cuscatlán International Airport (SAL) flights

Calendar48Weekly Planes
Duration5h 42mAverage Duration
Ticket$110Cheapest Price
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Comparing Your Travel Options

What companies run services between Santa Ana, CA, USA and Esquipulas, Chiquimula, Guatemala?

There is no direct connection from Santa Ana to Esquipulas. However, you can take the train to Los Angeles, walk to Los Angeles Union Station, take the bus to LAX Tom Bradley International Terminal, walk to Los Angeles International Airport (LAX) airport, fly to Cuscatlán International Airport (SAL), walk to San Salvador Airport, take the bus to San Salvador, take the bus to San Ignacio, drive to Nueva Ocotepeque, then take the bus to Esquipulas. Alternatively, you can take the train to Los Angeles, take the train to San Marcos Amtrak, walk to San Marcos, take the bus to Terminal Central de Autobuses del Norte, take the bus to Huixtla ADO, take the taxi to La Mesilla, take the bus to Calle Rooselvet, walk to Terminal de buses Oriente, take the bus to San Luis Jilotepeque, then take the taxi to Esquipulas.

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