There are 4 ways to get from Santa Ana to Appleton by plane, train, bus, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from John Wayne Airport Orange County (SNA) to Appleton International Airport (ATW)plane SNA - ATW
4h 7m$167–656Train, bus
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain Southwest Chief
- Take the bus from Chicago Bus Station to Appleton Transit Centerbus FlixBus 2550
2d 2h$628–1,349Bus
- Take the bus from Santa Ana to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Appleton Transit Centerbus
2d 7h$399–778Drive 2,059.4 mi
- Drive from Santa Ana to Appletoncar 2,059.4 mi
33h 3m$376–543
Santa Ana to Appleton by bus, train, and foot
Questions & Answers
The cheapest way to get from Santa Ana to Appleton is to fly which costs $160 - $700 and takes 4h 7m.
The fastest way to get from Santa Ana to Appleton is to fly which takes 4h 7m and costs $160 - $700.
No, there is no direct bus from Santa Ana to Appleton. However, there are services departing from Santa Ana and arriving at Appleton Transit Center via Los Angeles Union Station, St Louis Bus Station and Chicago Bus Station. The journey, including transfers, takes approximately 2 days 7h.
The distance between Santa Ana and Appleton is 1746 miles. The road distance is 2071.4 miles.
The best way to get from Santa Ana to Appleton without a car is to train and bus which takes 2 days 2h and costs $600 - $1,400.
It takes approximately 4h 7m to get from Santa Ana to Appleton, including transfers.
Santa Ana to Appleton bus services, operated by Greyhound Mexico, depart from Santa Ana station.
The best way to get from Santa Ana to Appleton is to fly which takes 4h 7m and costs $160 - $700. Alternatively, you can bus, which costs $390 - $800 and takes 2 days 7h.
Santa Ana to Appleton bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
Appleton is 2h ahead of Santa Ana. It is currently 4:10 AM in Santa Ana and 6:10 AM in Appleton.
What companies run services between Santa Ana, CA, USA and Appleton, WI, USA?
Allegiant Air, Delta, and two other airlines fly from John Wayne Airport Orange County (SNA) to Appleton International Airport (ATW) every 4 hours. Alternatively, you can take a bus from Santa Ana to Appleton Transit Center via Los Angeles Union Station, St Louis Bus Station, and Chicago Bus Station in around 2d 7h.
- Website
- aa.com
Flights from John Wayne Airport Orange County to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $130–600
Flights from John Wayne Airport Orange County to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 6m
- When
- Monday to Saturday
- Estimated price
- $140–650
- Website
- united.com
Flights from John Wayne Airport Orange County to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $130–600
Flights from John Wayne Airport Orange County to Appleton International Airport via Denver
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $120–600
- Website
- allegiantair.com
Flights from John Wayne Airport Orange County to Appleton International Airport
- Ave. Duration
- 3h 49m
- When
- Wednesday and Saturday
- Estimated price
- $120–600
- Website
- delta.com
Flights from John Wayne Airport Orange County to Appleton International Airport via Minneapolis
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $600–1,300
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Appleton Transit Center
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $24–45
- Schedules at
- flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Schedules at
- flixbus.com
- Phone
- +1-800-231-2222
- ifsr@greyhound.com
- Website
- greyhound.com.mx
Bus from Santa Ana to Los Angeles Union Station
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $9–13
- Schedules at
- greyhound.com.mx
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Los Angeles Union Station to St Louis Bus Station
- Ave. Duration
- 40h 15m
- Frequency
- Twice daily
- Estimated price
- $330–650
- Website
- https://www.greyhound.com/
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More Questions & Answers
Yes, the driving distance between Santa Ana to Appleton is 2071 miles. It takes approximately 33h 3m to drive from Santa Ana to Appleton.
Book your Santa Ana to Appleton bus tickets online with Omio.
There are 49+ hotels available in Appleton.














