There are 6 ways to get from Santa Ana to Mexicali by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus ABC  •  5 h 38 min

  1. Take the bus from Santa Ana, Ca to San Ysidro, Ca 9493 / ...
  2. Take the bus from Tijuana to Mexicali

$31 - $58

5 alternative options

Train, bus  •  6 h 6 min

  1. Take the train from Santa Ana Regional Transportation Center Amtrak to San Diego Santa Fe Depot Amtrak Pacific Surfliner
  2. Take the bus from Tijuana to Mexicali

$46 - $85

Bus Greyhound Mexico  •  9 h 35 min

  1. Take the bus from Santa Ana, Ca to San Ysidro, Ca 9493 / ...
  2. Take the bus from San Ysidro Transit Center to Mexicali Tijuana Airport-Ciudad Juárez

$57 - $97

Drive  •  3 h 33 min

  1. Drive from Santa Ana to Mexicali 206.6 miles

$20 - $30

Bus to Los Angeles, fly to El Centro  •  5 h 1 min

  1. Take the bus from Disneyland Hotel to Los Angeles Airport, CA
  2. Fly from Los Angeles (LAX) to El Centro (IPL) LAX - IPL

$64 - $165

Fly Santa Ana to Yuma, bus  •  8 h 37 min

  1. Fly from Santa Ana (SNA) to Yuma (YUM) SNA - YUM
  2. Take the bus from San Luis Rio Colorado to Mexicali Bus Terminal

$162 - $772

What companies run services between Santa Ana, CA, USA and Mexicali, Mexico?

You can take a bus from Santa Ana to Mexicali via San Ysidro, Ca and Tijuana in around 5 h 38 min.

Airlines
Alaska Airlines, Inc.
Website
alaskaair.com
Flights from Santa Ana to Yuma via Phoenix
Ave. Duration
3 h 21 min
When
Every day
Estimated price
$150 - $750
Flights from Santa Ana to Yuma via San Jose, Phoenix
Ave. Duration
6 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $850
American Airlines
Website
aa.com
Flights from Santa Ana to Yuma via Phoenix
Ave. Duration
3 h 21 min
When
Every day
Estimated price
$150 - $750
Mokulele
Website
mokuleleairlines.com
Flights from Los Angeles to El Centro
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$45 - $180
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Santa Ana Regional Transportation Center Amtrak to San Diego Santa Fe Depot Amtrak
Ave. Duration
2 h 6 min
Frequency
Every 2 hours
Estimated price
$29 - $65
Website
amtrak.com
Coach Seat
$29 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$40 - $65
Room
$150 - $220
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Santa Ana, Ca to San Ysidro, Ca
Ave. Duration
2 h 35 min
Frequency
Every 30 minutes
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Greyhound Mexico
Phone
01-800 890 6821
Website
greyhound.com.mx
Bus from Santa Ana to San Ysidro
Ave. Duration
2 h 21 min
Frequency
Twice daily
Estimated price
$40 - $55
Schedules at
greyhound.com.mx
Bus from San Ysidro Transit Center to Mexicali
Ave. Duration
6 h
Frequency
Twice daily
Estimated price
$40 - $60
Schedules at
greyhound.com.mx
ABC
Website
abc.com.mx
Bus from Tijuana to Mexicali
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$14 - $21
Schedules at
reservamos.mx
Book at
reservamos.mx
Bus from San Luis Rio Colorado to Mexicali Bus Terminal
Ave. Duration
1 h 15 min
Frequency
Every 2 hours
Estimated price
$6 - $9
Schedules at
reservamos.mx
Book at
reservamos.mx
Aguacaliente
Phone
6646212955
Email
atencionaclientes@autobusesaguacaliente.com.mx
Website
autobusesaguacaliente.com.mx
Bus from Tijuana to Mexicali
Ave. Duration
2 h
Frequency
Every 2 hours
Estimated price
$17
Schedules at
autobusesaguacaliente.com.mx
Gray Line AH
Phone
(714) 978-8855
Website
dre.coachusa.com
Bus from Disneyland Hotel to Los Angeles Airport, CA
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$25 - $35
Schedules at
dre.coachusa.com
Book at
dre.coachusa.com
Tufesa
Phone
016444102444
Website
tufesa.com.mx
Bus from San Luis Río Colorado to Mexicali Bus Terminal
Ave. Duration
54 min
Frequency
Every 4 hours
Estimated price
$6 - $14
Schedules at
tufesa.com.mx
Plus
$6 - $10
Platinum
$10 - $14
Ejecutivo
$9 - $14

Want to know more about travelling around Mexico

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Santa Ana and Mexicali is 257 km. The road distance is 331 km.

The cheapest way to get from Santa Ana to Mexicali is to drive which costs $20 - $30 and takes 3 h 33 min.

The quickest way to get from Santa Ana to Mexicali is to drive which takes 3 h 33 min and costs $20 - $30.

No, there is no direct bus from Santa Ana to Mexicali. However, there are services departing from Santa Ana, Ca and arriving at Mexicali via Tijuana. The journey, including transfers, takes approximately 5 h 38 min.

It takes approximately 5 h 38 min to get from Santa Ana to Mexicali, including transfers.